Combine Actos and Metformin

Drug Interactions and Combined Side Effects of
Actos

and Metformin

Combine Actos with Metformin. To make a decision about taking Actos and Metformin, click here for a Medication Risk Map showing their individual and Combined Risks

Actos and Metformin have 40 combined Side Effects total
17 are Life Threatening
13 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Actos.
Click here for Drug Interactions and Side Effects of Metformin.
Click here to compare Actos vs Metformin.

Uses of Actos

Actos is also known by the generic name Pioglitazone

USES:
Pioglitazone is an anti-diabetic drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes (non-insulin-dependent diabetes). It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar.

Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

Pioglitazone is used either alone or in combination with other anti-diabetic medications (such as metformin or a sulfonylurea such as glyburide). This medication should not be used to treat people with type 1 diabetes (insulin-dependent diabetes).

Uses of Metformin

USES:
Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes (non-insulin-dependent diabetes). Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.

Actos and Metformin Combined Have 17 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Any Disease of the Teeth - Tooth Disorder is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Broken Bone - Fractures is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Decrease in the Sharpness of Vision - Reduced Visual Acuity is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Heart Failure is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Increased Blood Acidity due to High Levels of Lactic Acid - Lactic Acidosis is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Macular Edema - Macular Retinal Edema is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Megaloblastic Anemia is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Stimulation of Ovarian Function - Ovulation Stimulation is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Visible Water Retention - Edema is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Water Retention - Body Fluid Retention is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Weight Gain is a Life Threatening Side Effect of Metformin and Actos combined

Critcal Seriouosness - Worsening of Chronic Heart Failure is a Life Threatening Side Effect of Metformin and Actos combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Actos and Metformin combined.

Actos and Metformin Combined have 13 Most Frequently Occurring Side Effects

Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Frequently Occurring Side Effect of Actos and Metformin combined

Any Disease of the Teeth - Tooth Disorder is a Frequently Occurring Side Effect of Actos and Metformin combined

Diarrhea is a Frequently Occurring Side Effect of Actos and Metformin combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Actos and Metformin combined

Gas - Flatulence is a Frequently Occurring Side Effect of Actos and Metformin combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Actos and Metformin combined

Muscle Pain - Myalgia is a Frequently Occurring Side Effect of Actos and Metformin combined

Sinus Irritation and Congestion - Sinusitis is a Frequently Occurring Side Effect of Actos and Metformin combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Actos and Metformin combined

Swelling of the Abdomen - Abdominal Swelling is a Frequently Occurring Side Effect of Actos and Metformin combined

Taste Problems - Dysgeusia is a Frequently Occurring Side Effect of Actos and Metformin combined

Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Actos and Metformin combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Actos and Metformin combined

Click for a searchable interactive map of all Side Effects associated with Actos and Metformin combined.

Actos and Metformin Drug-Drug Interactions

There are no drug-drug interactions between Actos and Metformin.

Actos has 14 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Actos.

Actos Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Decompensated Heart Failure - Suddenly Serious Symptoms of Heart Failure is a contraindication of Actos.

Severe Chronic Heart Failure - Severe Heart Failure is a contraindication of Actos.

Relative Contraindications

Chronic Heart Failure is a contraindication of Actos.

Disease of Liver - Liver Problems is a contraindication of Actos.

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Actos.

Contraindication Warnings

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Actos.

Body Fluid Retention - Water Retention is a contraindication of Actos.

Edema - Visible Water Retention is a contraindication of Actos.

Fever is a contraindication of Actos.

Fractures - Broken Bone is a contraindication of Actos.

Infection is a contraindication of Actos.

Macular Retinal Edema - Macular Edema is a contraindication of Actos.

Surgical Procedure - Recent Operation is a contraindication of Actos.

Trauma - Injury is a contraindication of Actos.

Metformin has 26 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Metformin.

Metformin Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Decompensated Heart Failure - Suddenly Serious Symptoms of Heart Failure is a contraindication of Metformin.

Alcohol Intoxication is a contraindication of Metformin.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Metformin.

Cardiogenic Shock - Blood Circulation Failure due to Serious Heart Condition is a contraindication of Metformin.

Dehydration - Extreme Loss of Body Water is a contraindication of Metformin.

Disease of Liver - Liver Problems is a contraindication of Metformin.

Ketoacidosis is a contraindication of Metformin.

Lactic Acidosis - Increased Blood Acidity due to High Levels of Lactic Acid is a contraindication of Metformin.

Metabolic Acidosis - Excess Body Acid is a contraindication of Metformin.

Myocardial Infarction - Heart Attack is a contraindication of Metformin.

Radiography with IV Iodinated Contrast Agent - X-Ray Study with Intravenous Iodine Contrast Agent is a contraindication of Metformin.

Renal Disease - Kidney Disease is a contraindication of Metformin.

Sepsis Syndrome is a contraindication of Metformin.

Severe Hypoxemia - Serious Lack of Oxygen in the Blood is a contraindication of Metformin.

Shock is a contraindication of Metformin.

Surgical Procedure - Recent Operation is a contraindication of Metformin.

Trauma - Injury is a contraindication of Metformin.

Relative Contraindications

Adrenocortical Insufficiency - Decreased Function of the Adrenal Gland is a contraindication of Metformin.

Debilitation - Weakened Patient is a contraindication of Metformin.

Fever is a contraindication of Metformin.

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Metformin.

Infection is a contraindication of Metformin.

Pituitary Insufficiency - Pituitary Hormone Deficiency is a contraindication of Metformin.

Severe Diarrhea is a contraindication of Metformin.

Severe Vomiting is a contraindication of Metformin.

Contraindication Warnings

Vitamin B12 Deficiency - Inadequate Vitamin B12 is a contraindication of Metformin.

Actos - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Metformin - Symptoms of overdose may include
severe drowsiness, severe nausea/vomiting/diarrhea, rapid breathing, slow/irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.