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Uses of Arimidex
 
Arimidex is also known by the generic name Anastrozole


USES:
This medication is used to treat breast cancer in women who have gone through "the change of life" (menopause). Anastrozole works by lowering estrogen hormone levels to help shrink tumors and slow their growth.


Uses of Tamoxifen
 
USES:
Tamoxifen is used to treat breast cancer that has spread to other parts of the body (metastatic breast cancer), to treat breast cancer in certain patients after surgery and radiation therapy, and to reduce the chances of breast cancer in high-risk patients.

This medication can block the growth of breast cancer. It works by interfering with the effects of estrogen in the breast tissue.


Arimidex and Tamoxifen Combined Have 38 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - Abnormally Long or Heavy Periods - Menorrhagia is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Anemia is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Angina is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Blood Clot - Thrombotic Disorder is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Blood Clot in Lung - Pulmonary Thromboembolism is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Blood Clot in Vein - Thrombophlebitis is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Broken Bone - Fractures is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Bullous Pemphigoid is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Cancer in the Lining of the Uterus - Endometrial Carcinoma is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Cataracts is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Chest Pain is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Disease of Inadequate Blood Flow to the Heart Muscle - Myocardial Ischemia is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Disease of the Cornea of the Eye - Disorder of Cornea is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Disease of the Retina of the Eye - Retinal Disorder is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Drowsiness - Drowsy is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Erythema Multiforme is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Feeling Weak - General Weakness is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Interstitial Pneumonitis is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Obstruction of a Blood Vessel by a Blood Clot - Thromboembolic Disorder is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Overgrowth of the Uterine Lining - Endometrial Hyperplasia is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Polyps of the Lining of the Uterus or the Endometrium - Endometrial Polyps is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Stroke - Cerebrovascular Accident is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Sudden Blindness and Pain Upon Moving the Eye - Optic Neuritis is a Life Threatening Side Effect of Tamoxifen and Arimidex combined
Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Tamoxifen and Arimidex combined

Arimidex and Tamoxifen Combined have 22 Most Frequently Occurring Side Effects
 
"Change of Life" Signs - Vasomotor Symptoms associated with Menopause is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Bone Pain is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Chest Pain is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Cough is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Diarrhea is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Dizzy - Dizziness is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Irritation of the Stomach or Intestines - Gastrointestinal Irritation is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Lymphedema is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Osteoporosis is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Pelvic Pain is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Rash - Skin Rash is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Temporary Redness of Face and Neck - Flushing is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Trouble Breathing - Dyspnea is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined
Weight Gain is a Frequently Occurring Side Effect of Arimidex and Tamoxifen combined

Arimidex and Tamoxifen Drug-Drug Interactions
 
When combined Arimidex and Tamoxifen have the following 1 Drug-Drug Interaction(s):
When combined Arimidex and Tamoxifen have the following interaction of Severe seriousness: Concurrent use of tamoxifen may result in decreased plasma levels and effectiveness of anastrozole and letrozole.

Arimidex has 5 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Arimidex.

Arimidex Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Arimidex.

Pregnancy is a contraindication of Arimidex.

Relative Contraindications 

Myocardial Ischemia - Disease of Inadequate Blood Flow to the Heart Muscle is a contraindication of Arimidex.

Contraindication Warnings 

Hypercholesterolemia - High Cholesterol is a contraindication of Arimidex.

Osteopenia - Decreased Calcification or Density of Bone is a contraindication of Arimidex.

Tamoxifen has 11 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Tamoxifen.

Tamoxifen Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Deep Venous Thrombosis - Blood Clot in a Deep Vein is a contraindication of Tamoxifen.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Tamoxifen.

Pregnancy is a contraindication of Tamoxifen.

Relative Contraindications 

Cerebrovascular Accident - Stroke is a contraindication of Tamoxifen.

Pulmonary Thromboembolism - Blood Clot in Lung is a contraindication of Tamoxifen.

Severe Thrombocytopenia - Severely Decreased Platelets is a contraindication of Tamoxifen.

Thromboembolic Disorder - Obstruction of a Blood Vessel by a Blood Clot is a contraindication of Tamoxifen.

Contraindication Warnings 

Cataracts is a contraindication of Tamoxifen.

Hypercalcemia - High Amount of Calcium in the Blood is a contraindication of Tamoxifen.

Leukopenia - Decreased White Blood Cells is a contraindication of Tamoxifen.

Visual Changes - Problems with Eyesight is a contraindication of Tamoxifen.
Arimidex - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Tamoxifen - Symptoms of overdose may include
shaking, unsteady walking, fainting, irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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