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Uses of Avandia
 
Avandia is also known by the generic name Rosiglitazone


USES:
Rosiglitazone is an anti-diabetic drug (thiazolidinedione-type, also called "glitazones") used with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes (non-insulin-dependent diabetes). You should only begin taking rosiglitazone when other drugs have not worked well or cannot be taken. If you are currently taking rosiglitazone and have good control of your blood sugars and no new side effects/symptoms, continue to take this drug as directed. Ask your doctor about the risks and benefits of this drug, since a small number of people have had serious side effects.

Rosiglitazone works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.


Uses of Metformin
 
USES:
Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes (non-insulin-dependent diabetes). Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.


Avandia and Metformin Combined Have 25 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Angina is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Broken Bone - Fractures is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Escape of Fluid into the Lungs - Pleural Effusions is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Fluid in the Lungs - Pulmonary Edema is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Heart Attack - Myocardial Infarction is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Heart Failure is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - High Cholesterol - Hypercholesterolemia is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Increased Blood Acidity due to High Levels of Lactic Acid - Lactic Acidosis is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Macular Edema - Macular Retinal Edema is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Megaloblastic Anemia is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Stroke - Cerebrovascular Accident is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Throwing Up - Vomiting is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Visible Water Retention - Edema is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Water Retention - Body Fluid Retention is a Life Threatening Side Effect of Metformin and Avandia combined
Critcal Seriouosness - Worsening of Chronic Heart Failure is a Life Threatening Side Effect of Metformin and Avandia combined

Avandia and Metformin Combined have 11 Most Frequently Occurring Side Effects
 
Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Frequently Occurring Side Effect of Avandia and Metformin combined
Backache - Back Pain is a Frequently Occurring Side Effect of Avandia and Metformin combined
Diarrhea is a Frequently Occurring Side Effect of Avandia and Metformin combined
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Avandia and Metformin combined
Gas - Flatulence is a Frequently Occurring Side Effect of Avandia and Metformin combined
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Avandia and Metformin combined
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Avandia and Metformin combined
Swelling of the Abdomen - Abdominal Swelling is a Frequently Occurring Side Effect of Avandia and Metformin combined
Taste Problems - Dysgeusia is a Frequently Occurring Side Effect of Avandia and Metformin combined
Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Avandia and Metformin combined
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Avandia and Metformin combined

Avandia and Metformin Drug-Drug Interactions
 
There are no drug-drug interactions between Avandia and Metformin.

Avandia has 19 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Avandia.

Avandia Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Decompensated Heart Failure - Suddenly Serious Symptoms of Heart Failure is a contraindication of Avandia.

Drug-Induced Hepatitis - Hepatitis caused by Drugs is a contraindication of Avandia.

Severe Chronic Heart Failure - Severe Heart Failure is a contraindication of Avandia.

Relative Contraindications 

Angina is a contraindication of Avandia.

Body Fluid Retention - Water Retention is a contraindication of Avandia.

Cerebrovascular Accident - Stroke is a contraindication of Avandia.

Chronic Heart Failure is a contraindication of Avandia.

Coronary Artery Disease - Disease of the Arteries of the Heart is a contraindication of Avandia.

Disease of Liver - Liver Problems is a contraindication of Avandia.

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Avandia.

Myocardial Infarction - Heart Attack is a contraindication of Avandia.

Myocardial Ischemia - Disease of Inadequate Blood Flow to the Heart Muscle is a contraindication of Avandia.

Osteopenia - Decreased Calcification or Density of Bone is a contraindication of Avandia.

Osteoporosis is a contraindication of Avandia.

Pulmonary Edema - Fluid in the Lungs is a contraindication of Avandia.

Contraindication Warnings 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Avandia.

Fractures - Broken Bone is a contraindication of Avandia.

Macular Retinal Edema - Macular Edema is a contraindication of Avandia.

Weight Gain is a contraindication of Avandia.

Metformin has 26 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Metformin.

Metformin Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Decompensated Heart Failure - Suddenly Serious Symptoms of Heart Failure is a contraindication of Metformin.

Alcohol Intoxication is a contraindication of Metformin.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Metformin.

Cardiogenic Shock - Blood Circulation Failure due to Serious Heart Condition is a contraindication of Metformin.

Dehydration - Extreme Loss of Body Water is a contraindication of Metformin.

Disease of Liver - Liver Problems is a contraindication of Metformin.

Ketoacidosis is a contraindication of Metformin.

Lactic Acidosis - Increased Blood Acidity due to High Levels of Lactic Acid is a contraindication of Metformin.

Metabolic Acidosis - Excess Body Acid is a contraindication of Metformin.

Myocardial Infarction - Heart Attack is a contraindication of Metformin.

Radiography with IV Iodinated Contrast Agent - X-Ray Study with Intravenous Iodine Contrast Agent is a contraindication of Metformin.

Renal Disease - Kidney Disease is a contraindication of Metformin.

Sepsis Syndrome is a contraindication of Metformin.

Severe Hypoxemia - Serious Lack of Oxygen in the Blood is a contraindication of Metformin.

Shock is a contraindication of Metformin.

Surgical Procedure - Recent Operation is a contraindication of Metformin.

Trauma - Injury is a contraindication of Metformin.

Relative Contraindications 

Adrenocortical Insufficiency - Decreased Function of the Adrenal Gland is a contraindication of Metformin.

Debilitation - Weakened Patient is a contraindication of Metformin.

Fever is a contraindication of Metformin.

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Metformin.

Infection is a contraindication of Metformin.

Pituitary Insufficiency - Pituitary Hormone Deficiency is a contraindication of Metformin.

Severe Diarrhea is a contraindication of Metformin.

Severe Vomiting is a contraindication of Metformin.

Contraindication Warnings 

Vitamin B12 Deficiency - Inadequate Vitamin B12 is a contraindication of Metformin.
Avandia - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Metformin - Symptoms of overdose may include
severe drowsiness, severe nausea/vomiting/diarrhea, rapid breathing, slow/irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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