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Heavy hITters
 

Uses of Celebrex
 
Celebrex is also known by the generic name Celecoxib


USES:
This medication is a nonsteroidal anti-inflammatory drug (NSAID), specifically a COX-2 inhibitor, which relieves pain and swelling (inflammation). It is used to treat arthritis, acute pain, and menstrual pain and discomfort. The pain and swelling relief provided by this medication helps you perform more of your normal daily activities.

This drug works by blocking the enzyme in your body that makes prostaglandins. Decreasing prostaglandins helps to reduce pain and swelling.


Uses of Lisinopril
 
USES:
Lisinopril is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure and to improve survival after a heart attack.

Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily.


Celebrex and Lisinopril Combined Have 78 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - A Rupture in the Wall of the Stomach or Intestine - Gastrointestinal Perforation is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Acute Kidney Disease - Acute Renal Disease is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Anemia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Angina is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Blistering Skin Diseases - Pemphigus is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Blood Clot in a Deep Vein - Deep Venous Thrombosis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Bloody Urine - Hematuria is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Chest Pain is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Condition in which Stomach Acid is Pushed Into the Esophagus - Gastroesophageal Reflux is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Depression is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Difficulty Swallowing - Dysphagia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Disease of the Arteries of the Heart - Coronary Artery Disease is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Disease of the Heart and Blood Vessels - Disease of Cardiovascular System is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Diverticulitis - Diverticulitis of Gastrointestinal Tract is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Dizzy - Dizziness is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Fever is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Fluid in the Lungs - Pulmonary Edema is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Hair Loss - Alopecia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Head and Neck Angioedema is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Heart Attack - Myocardial Infarction is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Heart Throbbing or Pounding - Palpitations is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Hemolytic Anemia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Hemorrhage Within the Skull - Intracranial Bleeding is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Hemorrhage from the Conjunctiva of the Eye - Conjunctival Hemorrhage is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Hiatal Hernia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - High Amount of Potassium in the Blood - Hyperkalemia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - High Blood Sugar - Hyperglycemia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - High Cholesterol - Hypercholesterolemia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Increase in the Number of Platelets in the Blood - Thrombocytosis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Inflammation of the Bladder - Cystitis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Inflammation of the Esophagus - Esophagitis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Intestinal Angioedema is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Joint Pain - Arthralgia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Kidney Damage - Nephrotoxicity is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Kidney Stone is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Leg Cramps - Cramps in Legs is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Liver Problems - Disease of Liver is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Low Amount of Potassium in the Blood - Hypokalemia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Pain in the Eye - Ocular Pain is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Pneumonia is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Red Blood in Bowel Movement - Bloody Stools is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Renal Papillary Necrosis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Rupture of a Tendon - Tendon Rupture is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Sensation of Spinning or Whirling - Vertigo is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Sinus Irritation and Congestion - Sinusitis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Skin Irritation is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Skin Rash with Sloughing - Exfoliative Dermatitis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Stomach or Intestinal Ulcer - Gastrointestinal Ulcer is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Stroke - Cerebrovascular Accident is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Syndrome of Inappropriate Antidiuretic Hormone Secretion - SIADH Syndrome is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Throwing Up - Vomiting is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Visible Water Retention - Edema is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Lisinopril and Celebrex combined
Critcal Seriouosness - Water Retention - Body Fluid Retention is a Life Threatening Side Effect of Lisinopril and Celebrex combined

Celebrex and Lisinopril Combined have 5 Most Frequently Occurring Side Effects
 
Cough is a Frequently Occurring Side Effect of Celebrex and Lisinopril combined
Diarrhea is a Frequently Occurring Side Effect of Celebrex and Lisinopril combined
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Celebrex and Lisinopril combined
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Celebrex and Lisinopril combined
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Celebrex and Lisinopril combined

Celebrex and Lisinopril Drug-Drug Interactions
 
When combined Celebrex and Lisinopril have the following 1 Drug-Drug Interaction(s):
When combined Celebrex and Lisinopril have the following interaction of Moderate seriousness: Concurrent use of ACE inhibitors or ARB's and NSAIDs may result in decreased antihypertensive effects. In patients with existing renal impairment, the use of these agents together may also result in further deterioration of renal clearance caused by renal hypoperfusion.

Celebrex has 24 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Celebrex.

Celebrex Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Post-operative from CABG Surgery - Time Immediately after Coronary Bypass Surgery is a contraindication of Celebrex.

Pregnancy is a contraindication of Celebrex.

Relative Contraindications 

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Celebrex.

Cerebrovascular Accident - Stroke is a contraindication of Celebrex.

Disease of Cardiovascular System - Disease of the Heart and Blood Vessels is a contraindication of Celebrex.

Gastrointestinal Hemorrhage - Bleeding of the Stomach or Intestines is a contraindication of Celebrex.

Gastrointestinal Perforation - A Rupture in the Wall of the Stomach or Intestine is a contraindication of Celebrex.

Gastrointestinal Ulcer - Stomach or Intestinal Ulcer is a contraindication of Celebrex.

Increased Cardiovascular Event Risk is a contraindication of Celebrex.

Myocardial Infarction - Heart Attack is a contraindication of Celebrex.

Peptic Ulcer - Ulcer from Stomach Acid is a contraindication of Celebrex.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Celebrex.

Thromboembolic Disorder - Obstruction of a Blood Vessel by a Blood Clot is a contraindication of Celebrex.

Tobacco Smoker - Tobacco Smoking is a contraindication of Celebrex.

Contraindication Warnings 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Celebrex.

Anemia is a contraindication of Celebrex.

Body Fluid Retention - Water Retention is a contraindication of Celebrex.

Bronchial Asthma - Asthma is a contraindication of Celebrex.

Chronic Heart Failure is a contraindication of Celebrex.

Dehydration - Extreme Loss of Body Water is a contraindication of Celebrex.

Disease of Liver - Liver Problems is a contraindication of Celebrex.

Edema - Visible Water Retention is a contraindication of Celebrex.

Hypertension - High Blood Pressure is a contraindication of Celebrex.

Renal Disease - Kidney Disease is a contraindication of Celebrex.

Lisinopril has 24 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Lisinopril.

Lisinopril Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Angioedema - Giant Hives is a contraindication of Lisinopril.

Hereditary Angioedema - Inherited Disorder of Continuing Episodes of Swelling is a contraindication of Lisinopril.

Intestinal Angioedema is a contraindication of Lisinopril.

Jaundice - Yellowing of Skin or Eyes from Liver Problems is a contraindication of Lisinopril.

Pregnancy is a contraindication of Lisinopril.

Relative Contraindications 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Lisinopril.

Acute Hepatic Failure - Acute Liver Failure is a contraindication of Lisinopril.

Hyperkalemia - High Amount of Potassium in the Blood is a contraindication of Lisinopril.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Lisinopril.

Hypotension - Abnormally Low Blood Pressure is a contraindication of Lisinopril.

Hypovolemia - Decreased Blood Volume is a contraindication of Lisinopril.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Lisinopril.

Renal Artery Stenosis is a contraindication of Lisinopril.

Renal Disease - Kidney Disease is a contraindication of Lisinopril.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Lisinopril.

Contraindication Warnings 

Aortic Valve Stenosis - Narrowing of the Aortic Heart Valve is a contraindication of Lisinopril.

Bone Marrow Depression - Decreased Function of Bone Marrow is a contraindication of Lisinopril.

Cerebrovascular Insufficiency - Brain Blood Flow Problem is a contraindication of Lisinopril.

Connective Tissue Disease - Disorder of the Connective Tissue is a contraindication of Lisinopril.

Disease of Liver - Liver Problems is a contraindication of Lisinopril.

Disorder of Electrolytes - Imbalance in Body Salts like Potassium and Sodium is a contraindication of Lisinopril.

Hemodialysis with High-Flux Membrane is a contraindication of Lisinopril.

Hypertrophic Cardiomyopathy is a contraindication of Lisinopril.

Immunosuppression - Reduction in the Body's Resistance to Infection is a contraindication of Lisinopril.
Celebrex - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, change in amount of urine, slow or shallow breathing, severe headache or loss of consciousness.

Lisinopril - Symptoms of overdose may include
severe dizziness, fainting.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

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