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Uses of Combivir
 
Combivir is also known by the generic name Lamivudine-Zidovudine


USES:
This product contains 2 drugs:
lamivudine and zidovudine. It is used with other medications to help control your HIV infection, thereby improving your quality of life. It helps to decrease the amount of HIV in your body so your immune system can work better. This product also lowers your risk of getting HIV disease complications (such as new infections, cancer). Both lamivudine and zidovudine belong to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).

Lamivudine/zidovudine is not a cure for HIV infection and it does not prevent the spread of HIV to others through sexual contact or blood contamination (such as sharing used needles).


Uses of Kaletra
 
Kaletra is also known by the generic name Lopinavir-Ritonavir


USES:
This combination product contains two medications, lopinavir and ritonavir. This product is used in combination with other medications to help control your HIV infection, thereby improving your quality of life. It also lowers your risk of getting HIV disease complications (e.g., opportunistic infections, cancer). Both lopinavir and ritonavir belong to a class of drugs known as HIV protease inhibitors. The ritonavir in this product helps the lopinavir to stay in your body. This effect builds up the amount of lopinavir in your body, increasing its effectiveness.

This lopinavir/ritonavir product is not a cure for HIV infection, and it does not prevent the spread of HIV to others through sexual contact or blood contamination (e.g., sharing used needles).


Combivir and Kaletra Combined Have 46 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Anemia is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Atrial Fibrillation is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Atrioventricular Heart Block - Atrioventricular Block is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Blood Clot in a Deep Vein - Deep Venous Thrombosis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Depression is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Diabetes - Diabetes Mellitus is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Disease of the Muscle of the Heart with Enlargement - Cardiomyopathy is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Disease of the Nerves - Neuropathy is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Enlarged Fatty Liver - Steatosis of Liver is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Enlarged Liver - Hepatomegaly is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Enlarged Spleen - Hypersplenism is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Erythema Multiforme is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Fluid in the Lungs - Pulmonary Edema is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Heart Attack - Myocardial Infarction is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - High Amount of Uric Acid in the Blood - Hyperuricemia is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - High Blood Sugar - Hyperglycemia is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Increased Blood Acidity due to High Levels of Lactic Acid - Lactic Acidosis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Infection is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Muscle Disease - Myopathy is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Painful, Red or Swollen Mouth - Stomatitis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Prolonged P-R Interval observed on EKG - Prolonged PR Interval is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Serious Muscle Damage that may Lead to Kidney Failure - Rhabdomyolysis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Small and Large Intestine Inflammation - Enterocolitis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Tumor - Neoplasm is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Underactive Thyroid - Hypothyroidism is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Vasculitis is a Life Threatening Side Effect of Kaletra and Combivir combined
Critcal Seriouosness - Wheezing is a Life Threatening Side Effect of Kaletra and Combivir combined

Combivir and Kaletra Combined have 12 Most Frequently Occurring Side Effects
 
Abnormal Fat Distribution associated with HIV - Lipodystrophy associated with Human Immunodeficiency Virus Infection is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Acute Inflammation of the Pancreas - Acute Pancreatitis is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Decreased White Blood Cells - Leukopenia is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Diarrhea is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Numbness and Tingling - Paresthesia is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Combivir and Kaletra combined
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Combivir and Kaletra combined

Combivir and Kaletra Drug-Drug Interactions
 
There are no drug-drug interactions between Combivir and Kaletra.

Combivir has 18 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Combivir.

Combivir Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Combivir.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Combivir.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Combivir.

Lactic Acidosis - Increased Blood Acidity due to High Levels of Lactic Acid is a contraindication of Combivir.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Combivir.

Steatosis of Liver - Enlarged Fatty Liver is a contraindication of Combivir.

Relative Contraindications 

Anemia is a contraindication of Combivir.

Bone Marrow Depression - Decreased Function of Bone Marrow is a contraindication of Combivir.

Hepatomegaly - Enlarged Liver is a contraindication of Combivir.

Myopathy - Muscle Disease is a contraindication of Combivir.

Myositis - Muscle Inflammation is a contraindication of Combivir.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Combivir.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Combivir.

Contraindication Warnings 

Disease of Liver - Liver Problems is a contraindication of Combivir.

Drug Resistance to Anti-retroviral Therapy is a contraindication of Combivir.

Obesity - Overweight is a contraindication of Combivir.

Renal Disease - Kidney Disease is a contraindication of Combivir.

Toxic Amblyopia - Vision Changes caused by Medications is a contraindication of Combivir.

Kaletra has 26 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Kaletra.

Kaletra Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Kaletra.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Kaletra.

Relative Contraindications 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Kaletra.

Chronic Hepatitis C is a contraindication of Kaletra.

Chronic Type B Viral Hepatitis - Chronic Hepatitis B is a contraindication of Kaletra.

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Kaletra.

Diabetes Mellitus - Diabetes is a contraindication of Kaletra.

Disease of Liver - Liver Problems is a contraindication of Kaletra.

Hemophilia A is a contraindication of Kaletra.

Hemophilia B - Blood Clotting Disorder from Clotting Factor IX is a contraindication of Kaletra.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Kaletra.

Hypertriglyceridemia - High Amount of Triglyceride in the Blood is a contraindication of Kaletra.

Hypokalemia - Low Amount of Potassium in the Blood is a contraindication of Kaletra.

Hypomagnesemia - Low Amount of Magnesium in the Blood is a contraindication of Kaletra.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Kaletra.

Torsades de Pointes - Very Rapid Heartbeat - Torsades de Pointes is a contraindication of Kaletra.

Contraindication Warnings 

Cardiomyopathy - Disease of the Muscle of the Heart with Enlargement is a contraindication of Kaletra.

Complete Atrioventricular Block - Complete Heart Block is a contraindication of Kaletra.

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Kaletra.

First Degree Atrioventricular Heart Block is a contraindication of Kaletra.

Hyperbilirubinemia - High Amount of Bilirubin in the Blood is a contraindication of Kaletra.

Hyperglycemia - High Blood Sugar is a contraindication of Kaletra.

Mixed Hyperlipidemia - Combined High Blood Cholesterol and Triglyceride Level is a contraindication of Kaletra.

Myocardial Ischemia - Disease of Inadequate Blood Flow to the Heart Muscle is a contraindication of Kaletra.

Second Degree Atrioventricular Heart Block is a contraindication of Kaletra.

Structural Disorder of Heart is a contraindication of Kaletra.
Combivir - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Kaletra - Symptoms of overdose may include
change in amount of urine; or numbness or tingling in the arms, hands, legs, or feet.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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