Combine Cymbalta and Methadone

Drug Interactions and Combined Side Effects of
Cymbalta

and Methadone

Combine Cymbalta with Methadone. To make a decision about taking Cymbalta and Methadone, click here for a Medication Risk Map showing their individual and Combined Risks

Cymbalta and Methadone have 117 combined Side Effects total
51 are Life Threatening
16 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Cymbalta.
Click here for Drug Interactions and Side Effects of Methadone.
Click here to compare Cymbalta vs Methadone.

Uses of Cymbalta

Cymbalta is also known by the generic name Duloxetine

USES:
Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).

Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

Uses of Methadone

USES:
This medication is used to treat moderate to severe pain. Methadone belongs to a class of drugs known as narcotic (opiate) analgesics. It works in the brain to change how your body feels and responds to pain.

This medication is also used to treat addiction to narcotic drugs (such as heroin) as part of an approved treatment program. It helps prevent withdrawal symptoms caused by stopping other narcotic drugs.

Cymbalta and Methadone Combined Have 51 Life Threatening (Major) Side Effects

Critcal Seriouosness - A Spasm of the Larynx - Laryngismus is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Bruise - Bruising is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Burning Stomach - Gastritis is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Change in Pulse - Pulse Changes is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Collapsed Portion of Lung - Atelectasis is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Complete Stoppage of the Heart - Cardiac Arrest is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Depression is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Fluid in the Lungs - Pulmonary Edema is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Hemorrhage of Blood Under the Skin - Ecchymosis is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Hemorrhage is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Increased Spinal Fluid Pressure - Increased Cerebrospinal Fluid Pressure is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Lung Failure causing Loss of Breath - Respiratory Insufficiency is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Needing to Urinate Immediately - Urinary Urgency is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Red Blood in Bowel Movement - Bloody Stools is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Redness of Skin - Erythema is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Shock is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Significant Decrease in Lung Function - Respiratory Depression is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Suicidal is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Syndrome of Inappropriate Antidiuretic Hormone Secretion - SIADH Syndrome is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Very Rapid Heartbeat - Torsades de Pointes - Torsades de Pointes is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Methadone and Cymbalta combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Methadone and Cymbalta combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Cymbalta and Methadone combined.

Cymbalta and Methadone Combined have 16 Most Frequently Occurring Side Effects

Abnormally Low Blood Pressure - Hypotension is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Blurred Vision is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Feeling Faint - Fainting is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Low Energy - Fatigue is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Not Feeling Well - Malaise is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Cymbalta and Methadone combined

Click for a searchable interactive map of all Side Effects associated with Cymbalta and Methadone combined.

Cymbalta and Methadone Drug-Drug Interactions

There are no drug-drug interactions between Cymbalta and Methadone.

Cymbalta has 25 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Cymbalta.

Cymbalta Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Neuroleptic Malignant Syndrome is a contraindication of Cymbalta.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Cymbalta.

Relative Contraindications

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Cymbalta.

Alcoholic Liver Damage - Hardening of the Liver caused by Alcohol is a contraindication of Cymbalta.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Cymbalta.

Chronic Hepatitis - Chronic Inflammation of the Liver is a contraindication of Cymbalta.

Disease of Liver - Liver Problems is a contraindication of Cymbalta.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Cymbalta.

Hepatitis is a contraindication of Cymbalta.

Jaundice - Yellowing of Skin or Eyes from Liver Problems is a contraindication of Cymbalta.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Cymbalta.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Cymbalta.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Cymbalta.

Contraindication Warnings

Bipolar Disorder - Manic-Depression is a contraindication of Cymbalta.

Epilepsy - Epileptic Seizure is a contraindication of Cymbalta.

Gastrointestinal Hypomotility - Decreased Motility Function of Stomach or Intestines is a contraindication of Cymbalta.

Hyperglycemia - High Blood Sugar is a contraindication of Cymbalta.

Hypertension - High Blood Pressure is a contraindication of Cymbalta.

Hypomania - Mild Degree of Mania is a contraindication of Cymbalta.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Cymbalta.

Increased Risk of Bleeding is a contraindication of Cymbalta.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Cymbalta.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Cymbalta.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Cymbalta.

Urinary Retention - Cannot Empty Bladder is a contraindication of Cymbalta.

Methadone has 27 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Methadone.

Methadone Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Hypercapnia - Excess Amount of Carbon Dioxide in the Blood is a contraindication of Methadone.

Paralytic Ileus - Paralysis of the Intestines is a contraindication of Methadone.

Pseudomembranous Enterocolitis - Severe Bloody Diarrhea from Antibiotics is a contraindication of Methadone.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Methadone.

Torsades de Pointes - Very Rapid Heartbeat - Torsades de Pointes is a contraindication of Methadone.

Toxin-Mediated Diarrhea - Toxin from Microorganisms causing Diarrhea is a contraindication of Methadone.

Relative Contraindications

Acute Asthma Attack - Asthma Attack is a contraindication of Methadone.

Bradycardia - Slow Heartbeat is a contraindication of Methadone.

Chronic Disease of Respiratory System - Chronic Lung or Breathing Passage Problem is a contraindication of Methadone.

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Methadone.

Inflammatory Bowel Disease is a contraindication of Methadone.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Methadone.

Contraindication Warnings

Acute Abdominal Pain - Intense Abdominal Pain is a contraindication of Methadone.

Benign Prostatic Hypertrophy - Enlarged Prostate is a contraindication of Methadone.

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Methadone.

Disease of Liver - Liver Problems is a contraindication of Methadone.

Epilepsy - Epileptic Seizure is a contraindication of Methadone.

Gallbladder Disease - Disease of the Gallbladder is a contraindication of Methadone.

Head Injury is a contraindication of Methadone.

Hypotension - Abnormally Low Blood Pressure is a contraindication of Methadone.

Hypothyroidism - Underactive Thyroid is a contraindication of Methadone.

Intracranial Hypertension - High Pressure Within the Skull is a contraindication of Methadone.

Mood Changes is a contraindication of Methadone.

Procedure on Urinary System - Urinary Tract Surgery is a contraindication of Methadone.

Renal Disease - Kidney Disease is a contraindication of Methadone.

Substance Abuse - Misuse or Excessive Use of Drugs is a contraindication of Methadone.

Urethral Stricture - Narrowing of the Tube that Empties Urine From the Bladder is a contraindication of Methadone.

Cymbalta - Symptoms of overdose may include
severe drowsiness, fainting.

Methadone - Symptoms of overdose may include
slow/shallow breathing, slow heartbeat, loss of consciousness.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.