Combine Cymbalta and Tamoxifen

Drug Interactions and Combined Side Effects of
Cymbalta

and Tamoxifen

Combine Cymbalta with Tamoxifen. To make a decision about taking Cymbalta and Tamoxifen, click here for a Medication Risk Map showing their individual and Combined Risks

Cymbalta and Tamoxifen have 108 combined Side Effects total
46 are Life Threatening
11 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Cymbalta.
Click here for Drug Interactions and Side Effects of Tamoxifen.
Click here to compare Cymbalta vs Tamoxifen.

Uses of Cymbalta

Cymbalta is also known by the generic name Duloxetine

USES:
Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).

Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

Uses of Tamoxifen

USES: Tamoxifen is used to treat breast cancer that has spread to other parts of the body (metastatic breast cancer), to treat breast cancer in certain patients after surgery and radiation therapy, and to reduce the chances of breast cancer in high-risk patients. This medication can block the growth of breast cancer. It works by interfering with the effects of estrogen in the breast tissue.

Cymbalta and Tamoxifen Combined Have 46 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Blood Clot - Thrombotic Disorder is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Blood Clot in Lung - Pulmonary Thromboembolism is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Bruise - Bruising is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Bullous Pemphigoid is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Burning Stomach - Gastritis is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Cancer in the Lining of the Uterus - Endometrial Carcinoma is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Cataracts is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Disease of the Cornea of the Eye - Disorder of Cornea is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Disease of the Retina of the Eye - Retinal Disorder is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Drowsiness - Drowsy is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Erythema Multiforme is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Feeling Weak - General Weakness is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Hemorrhage of Blood Under the Skin - Ecchymosis is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Hemorrhage is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Interstitial Pneumonitis is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Needing to Urinate Immediately - Urinary Urgency is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Obstruction of a Blood Vessel by a Blood Clot - Thromboembolic Disorder is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Overgrowth of the Uterine Lining - Endometrial Hyperplasia is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Polyps of the Lining of the Uterus or the Endometrium - Endometrial Polyps is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Red Blood in Bowel Movement - Bloody Stools is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Redness of Skin - Erythema is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Stroke - Cerebrovascular Accident is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Sudden Blindness and Pain Upon Moving the Eye - Optic Neuritis is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Suicidal is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Syndrome of Inappropriate Antidiuretic Hormone Secretion - SIADH Syndrome is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Tamoxifen and Cymbalta combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Cymbalta and Tamoxifen combined.

Cymbalta and Tamoxifen Combined have 11 Most Frequently Occurring Side Effects

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Low Energy - Fatigue is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Cymbalta and Tamoxifen combined

Click for a searchable interactive map of all Side Effects associated with Cymbalta and Tamoxifen combined.

Cymbalta and Tamoxifen Drug-Drug Interactions

When combined Cymbalta and Tamoxifen have the following 1 Drug-Drug Interaction(s):

When combined Cymbalta and Tamoxifen have the following interaction of Serious seriousness: Concurrent use of inhibitors of CYP P-450-2D6 may decrease the effectiveness of tamoxifen in preventing breast cancer recurrence. Concurrent use of amiodarone or thioridazine may increase the risk of potentially life-threatening cardiac arrhythmias, including torsades de pointes.

Click for a searchable interactive map of all interactions between Cymbalta and Tamoxifen.

Cymbalta has 25 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Cymbalta.

Cymbalta Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Neuroleptic Malignant Syndrome is a contraindication of Cymbalta.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Cymbalta.

Relative Contraindications

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Cymbalta.

Alcoholic Liver Damage - Hardening of the Liver caused by Alcohol is a contraindication of Cymbalta.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Cymbalta.

Chronic Hepatitis - Chronic Inflammation of the Liver is a contraindication of Cymbalta.

Disease of Liver - Liver Problems is a contraindication of Cymbalta.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Cymbalta.

Hepatitis is a contraindication of Cymbalta.

Jaundice - Yellowing of Skin or Eyes from Liver Problems is a contraindication of Cymbalta.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Cymbalta.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Cymbalta.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Cymbalta.

Contraindication Warnings

Bipolar Disorder - Manic-Depression is a contraindication of Cymbalta.

Epilepsy - Epileptic Seizure is a contraindication of Cymbalta.

Gastrointestinal Hypomotility - Decreased Motility Function of Stomach or Intestines is a contraindication of Cymbalta.

Hyperglycemia - High Blood Sugar is a contraindication of Cymbalta.

Hypertension - High Blood Pressure is a contraindication of Cymbalta.

Hypomania - Mild Degree of Mania is a contraindication of Cymbalta.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Cymbalta.

Increased Risk of Bleeding is a contraindication of Cymbalta.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Cymbalta.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Cymbalta.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Cymbalta.

Urinary Retention - Cannot Empty Bladder is a contraindication of Cymbalta.

Tamoxifen has 11 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Tamoxifen.

Tamoxifen Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Deep Venous Thrombosis - Blood Clot in a Deep Vein is a contraindication of Tamoxifen.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Tamoxifen.

Pregnancy is a contraindication of Tamoxifen.

Relative Contraindications

Cerebrovascular Accident - Stroke is a contraindication of Tamoxifen.

Pulmonary Thromboembolism - Blood Clot in Lung is a contraindication of Tamoxifen.

Severe Thrombocytopenia - Severely Decreased Platelets is a contraindication of Tamoxifen.

Thromboembolic Disorder - Obstruction of a Blood Vessel by a Blood Clot is a contraindication of Tamoxifen.

Contraindication Warnings

Cataracts is a contraindication of Tamoxifen.

Hypercalcemia - High Amount of Calcium in the Blood is a contraindication of Tamoxifen.

Leukopenia - Decreased White Blood Cells is a contraindication of Tamoxifen.

Visual Changes - Problems with Eyesight is a contraindication of Tamoxifen.

Cymbalta - Symptoms of overdose may include
severe drowsiness, fainting.

Tamoxifen - Symptoms of overdose may include
shaking, unsteady walking, fainting, irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.