Combine Cymbalta and Tramadol

Drug Interactions and Combined Side Effects of
Cymbalta

and Tramadol

Combine Cymbalta with Tramadol. To make a decision about taking Cymbalta and Tramadol, click here for a Medication Risk Map showing their individual and Combined Risks

Cymbalta and Tramadol have 112 combined Side Effects total
44 are Life Threatening
14 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Cymbalta.
Click here for Drug Interactions and Side Effects of Tramadol.
Click here to compare Cymbalta vs Tramadol.

Uses of Cymbalta

Cymbalta is also known by the generic name Duloxetine

USES:
Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).

Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

Uses of Tramadol

USES: This medication is used to help relieve moderate to moderately severe pain. Tramadol is similar to narcotic analgesics. It works in the brain to change how your body feels and responds to pain.

Cymbalta and Tramadol Combined Have 44 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Blood Pressure Drop Upon Standing - Orthostatic Hypotension is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Blurred Vision is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Bruise - Bruising is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Burning Stomach - Gastritis is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Cannot Empty Bladder - Urinary Retention is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Frequent Urination - Increased Urinary Frequency is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Hemorrhage of Blood Under the Skin - Ecchymosis is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Hemorrhage is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Involuntary Quivering - Tremors is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Loss of Memory - Memory Impairment is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Needing to Urinate Immediately - Urinary Urgency is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Red Blood in Bowel Movement - Bloody Stools is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Redness of Skin - Erythema is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Small Skin Blister - Blistering Skin is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Suicidal is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Syndrome of Inappropriate Antidiuretic Hormone Secretion - SIADH Syndrome is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Tramadol and Cymbalta combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Cymbalta and Tramadol combined.

Cymbalta and Tramadol Combined have 14 Most Frequently Occurring Side Effects

Anxious - Anxiety is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Diarrhea is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Gas - Flatulence is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Low Energy - Fatigue is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Cymbalta and Tramadol combined

Click for a searchable interactive map of all Side Effects associated with Cymbalta and Tramadol combined.

Cymbalta and Tramadol Drug-Drug Interactions

When combined Cymbalta and Tramadol have the following 1 Drug-Drug Interaction(s):

When combined Cymbalta and Tramadol have the following interaction of Serious seriousness: Concurrent administration may result in serotonin syndrome. Symptoms of serotonin syndrome may include irritability, altered consciousness, double vision, nausea, confusion, anxiety, hyperthermia, increased muscle tone, rigidity, myoclonus, rapid fluctuations in vital signs, and coma. Serotonin syndrome may result in death. Concurrent administration may also increase the risk of seizures and suicide and decrease the effectiveness of tramadol.

Click for a searchable interactive map of all interactions between Cymbalta and Tramadol.

Cymbalta has 25 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Cymbalta.

Cymbalta Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Neuroleptic Malignant Syndrome is a contraindication of Cymbalta.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Cymbalta.

Relative Contraindications

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Cymbalta.

Alcoholic Liver Damage - Hardening of the Liver caused by Alcohol is a contraindication of Cymbalta.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Cymbalta.

Chronic Hepatitis - Chronic Inflammation of the Liver is a contraindication of Cymbalta.

Disease of Liver - Liver Problems is a contraindication of Cymbalta.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Cymbalta.

Hepatitis is a contraindication of Cymbalta.

Jaundice - Yellowing of Skin or Eyes from Liver Problems is a contraindication of Cymbalta.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Cymbalta.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Cymbalta.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Cymbalta.

Contraindication Warnings

Bipolar Disorder - Manic-Depression is a contraindication of Cymbalta.

Epilepsy - Epileptic Seizure is a contraindication of Cymbalta.

Gastrointestinal Hypomotility - Decreased Motility Function of Stomach or Intestines is a contraindication of Cymbalta.

Hyperglycemia - High Blood Sugar is a contraindication of Cymbalta.

Hypertension - High Blood Pressure is a contraindication of Cymbalta.

Hypomania - Mild Degree of Mania is a contraindication of Cymbalta.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Cymbalta.

Increased Risk of Bleeding is a contraindication of Cymbalta.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Cymbalta.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Cymbalta.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Cymbalta.

Urinary Retention - Cannot Empty Bladder is a contraindication of Cymbalta.

Tramadol has 22 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Tramadol.

Tramadol Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Alcohol Intoxication is a contraindication of Tramadol.

Benzodiazepine Toxicity - Adverse Effect of Benzodiazepine-Based Tranquilizer is a contraindication of Tramadol.

Opioid Toxicity - Toxic Amount of Narcotics in the Body is a contraindication of Tramadol.

Pregnancy is a contraindication of Tramadol.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Tramadol.

Substance Abuse - Misuse or Excessive Use of Drugs is a contraindication of Tramadol.

Suicidal is a contraindication of Tramadol.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Tramadol.

Relative Contraindications

Abrupt Drug Withdrawal Causing Life-Threatening Sequelae - Sudden Drug Withdrawal Causing Life-Threatening Reactions is a contraindication of Tramadol.

Alcohol Withdrawal Syndrome - Symptoms from Alcohol Withdrawal is a contraindication of Tramadol.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Tramadol.

CNS Depression - Abnormal Nervous System Function Affecting Mental Alertness is a contraindication of Tramadol.

Central Nervous System Infection - Nervous System Infection of Brain and Spinal Cord is a contraindication of Tramadol.

Depression is a contraindication of Tramadol.

Epilepsy - Epileptic Seizure is a contraindication of Tramadol.

Head Injury is a contraindication of Tramadol.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Tramadol.

Intracranial Hypertension - High Pressure Within the Skull is a contraindication of Tramadol.

Lower Seizure Threshold is a contraindication of Tramadol.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Tramadol.

Seizure Disorder - Seizures is a contraindication of Tramadol.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Tramadol.

Cymbalta - Symptoms of overdose may include
severe drowsiness, fainting.

Tramadol - Symptoms of overdose may include
slow breathing, slow/irregular heartbeat, loss of consciousness, seizure.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.