Combine Cymbalta and Wellbutrin

Drug Interactions and Combined Side Effects of
Cymbalta

and Wellbutrin

Combine Cymbalta with Wellbutrin. To make a decision about taking Cymbalta and Wellbutrin, click here for a Medication Risk Map showing their individual and Combined Risks

Cymbalta and Wellbutrin have 106 combined Side Effects total
43 are Life Threatening
16 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Cymbalta.
Click here for Drug Interactions and Side Effects of Wellbutrin.
Click here to compare Cymbalta vs Wellbutrin.

Uses of Cymbalta

Cymbalta is also known by the generic name Duloxetine

USES:
Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).

Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

Uses of Wellbutrin

Wellbutrin is also known by the generic name Bupropion Hcl USES: Bupropion is used to treat depression. It can improve your mood and feelings of well-being. It may work by helping to restore the balance of certain natural chemicals (neurotransmitters) in your brain.

Cymbalta and Wellbutrin Combined Have 43 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Anxious - Anxiety is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Bruise - Bruising is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Burning Stomach - Gastritis is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Cannot Focus Thoughts - Concentration Difficulty is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Chest Pain is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Delusions - Delusional Disorder is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Feeling Restless - Feeling Agitated is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Hemorrhage of Blood Under the Skin - Ecchymosis is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Hemorrhage is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Joint Pain - Arthralgia is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Mental Disorder with Loss of Normal Personality & Reality - Psychotic Disorder is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Needing to Urinate Immediately - Urinary Urgency is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Painful Periods - Dysmenorrhea is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Paranoia - Paranoid Disorder is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Red Blood in Bowel Movement - Bloody Stools is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Redness of Skin - Erythema is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Ringing in the Ears - Tinnitus is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Severe Headache - Severe Headache Disorder is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Suicidal is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Syndrome of Inappropriate Antidiuretic Hormone Secretion - SIADH Syndrome is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Thoughts of Hurting or Killing Others - Homicidal Ideation is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Wellbutrin and Cymbalta combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Cymbalta and Wellbutrin combined.

Cymbalta and Wellbutrin Combined have 16 Most Frequently Occurring Side Effects

Anxious - Anxiety is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Feeling Restless - Feeling Agitated is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Gas - Flatulence is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Low Energy - Fatigue is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Weight Loss is a Frequently Occurring Side Effect of Cymbalta and Wellbutrin combined

Click for a searchable interactive map of all Side Effects associated with Cymbalta and Wellbutrin combined.

Cymbalta and Wellbutrin Drug-Drug Interactions

When combined Cymbalta and Wellbutrin have the following 1 Drug-Drug Interaction(s):

When combined Cymbalta and Wellbutrin have the following interaction of Moderate seriousness: Concurrent use of bupropion and an antidepressant may result in additive effects on the seizure threshold, increasing the risk of seizures.(1,2) Concurrent use may increase levels of and side effects from desipramine.(1,2)

Click for a searchable interactive map of all interactions between Cymbalta and Wellbutrin.

Cymbalta has 25 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Cymbalta.

Cymbalta Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Neuroleptic Malignant Syndrome is a contraindication of Cymbalta.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Cymbalta.

Relative Contraindications

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Cymbalta.

Alcoholic Liver Damage - Hardening of the Liver caused by Alcohol is a contraindication of Cymbalta.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Cymbalta.

Chronic Hepatitis - Chronic Inflammation of the Liver is a contraindication of Cymbalta.

Disease of Liver - Liver Problems is a contraindication of Cymbalta.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Cymbalta.

Hepatitis is a contraindication of Cymbalta.

Jaundice - Yellowing of Skin or Eyes from Liver Problems is a contraindication of Cymbalta.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Cymbalta.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Cymbalta.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Cymbalta.

Contraindication Warnings

Bipolar Disorder - Manic-Depression is a contraindication of Cymbalta.

Epilepsy - Epileptic Seizure is a contraindication of Cymbalta.

Gastrointestinal Hypomotility - Decreased Motility Function of Stomach or Intestines is a contraindication of Cymbalta.

Hyperglycemia - High Blood Sugar is a contraindication of Cymbalta.

Hypertension - High Blood Pressure is a contraindication of Cymbalta.

Hypomania - Mild Degree of Mania is a contraindication of Cymbalta.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Cymbalta.

Increased Risk of Bleeding is a contraindication of Cymbalta.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Cymbalta.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Cymbalta.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Cymbalta.

Urinary Retention - Cannot Empty Bladder is a contraindication of Cymbalta.

Wellbutrin has 28 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Wellbutrin.

Wellbutrin Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Anorexia Nervosa is a contraindication of Wellbutrin.

Bulimia Nervosa - Bulimia is a contraindication of Wellbutrin.

Seizure Disorder - Seizures is a contraindication of Wellbutrin.

Seizure due to Abrupt Benzodiazepine Withdrawal - Seizure caused by Sudden Withdrawal of Benzodiazepine is a contraindication of Wellbutrin.

Seizure due to Alcohol Withdrawal - Seizure caused by Stopping Alcohol Use is a contraindication of Wellbutrin.

Relative Contraindications

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Wellbutrin.

Central Nervous System Neoplasm - Tumor of the Brain or Spinal Cord is a contraindication of Wellbutrin.

Cerebral Metastases - Spread of Cancer to the Brain is a contraindication of Wellbutrin.

Feeling Agitated - Feeling Restless is a contraindication of Wellbutrin.

Head Injury is a contraindication of Wellbutrin.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Wellbutrin.

Hostility - Feeling Anger Toward Something is a contraindication of Wellbutrin.

Lower Seizure Threshold is a contraindication of Wellbutrin.

Manic Bipolar Disorder - Manic Phase of Manic-Depression is a contraindication of Wellbutrin.

Mood Changes is a contraindication of Wellbutrin.

Opioid Dependence - Narcotic Addiction is a contraindication of Wellbutrin.

Panic Disorder is a contraindication of Wellbutrin.

Renal Disease - Kidney Disease is a contraindication of Wellbutrin.

Sedative Drug Dependence is a contraindication of Wellbutrin.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Wellbutrin.

Stimulant Drug Dependence is a contraindication of Wellbutrin.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Wellbutrin.

Uncontrolled Diabetes Mellitus - Diabetes that is Not Under Control is a contraindication of Wellbutrin.

Contraindication Warnings

Disease of Liver - Liver Problems is a contraindication of Wellbutrin.

Hypertension - High Blood Pressure is a contraindication of Wellbutrin.

Myocardial Infarction - Heart Attack is a contraindication of Wellbutrin.

Psychotic Disorder - Mental Disorder with Loss of Normal Personality & Reality is a contraindication of Wellbutrin.

Weight Loss is a contraindication of Wellbutrin.

Cymbalta - Symptoms of overdose may include
severe drowsiness, fainting.

Wellbutrin - Symptoms of overdose may include
seizures, hallucinations, fast or slow heart rate, loss of consciousness.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.