Combine Cymbalta and Zanaflex

Drug Interactions and Combined Side Effects of
Cymbalta

and Zanaflex

Combine Cymbalta with Zanaflex. To make a decision about taking Cymbalta and Zanaflex, click here for a Medication Risk Map showing their individual and Combined Risks

Cymbalta and Zanaflex have 118 combined Side Effects total
47 are Life Threatening
33 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Cymbalta.
Click here for Drug Interactions and Side Effects of Zanaflex.
Click here to compare Cymbalta vs Zanaflex.

Uses of Cymbalta

Cymbalta is also known by the generic name Duloxetine

USES:
Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).

Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

Uses of Zanaflex

Zanaflex is also known by the generic name Tizanidine

USES:
This medication is used to treat muscle tightness and cramping (spasm) caused by conditions such as multiple sclerosis or spinal injury. Decreasing spasms can reduce pain and improve your ability to move around. Tizanidine is a short-acting muscle relaxant that works by blocking certain nerve signals from the spine to the brain (alpha adrenergic agonist).

Cymbalta and Zanaflex Combined Have 47 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Anemia is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Blood Disorder - Blood Dyscrasias is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Bruise - Bruising is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Burning Stomach - Gastritis is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Delusions - Delusional Disorder is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Fever is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Hemorrhage of Blood Under the Skin - Ecchymosis is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Hemorrhage is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Increase of White Blood Cells - Leukocytosis is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Infection due to the Candida Fungus - Candidiasis is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Kidney Stone is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Mental Impairment is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Needing to Urinate Immediately - Urinary Urgency is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Nervous - Nervousness is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Pain in the Eye - Ocular Pain is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Problems with Eyesight - Visual Changes is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Red Blood in Bowel Movement - Bloody Stools is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Redness of Skin - Erythema is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Skin Ulcer is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Suicidal is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Syndrome of Inappropriate Antidiuretic Hormone Secretion - SIADH Syndrome is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Underactive Thyroid - Hypothyroidism is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Urinary Tract Infection - Urinary Tract Infections is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Vision Changes caused by Medications - Toxic Amblyopia is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Visual Field Defect is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Zanaflex and Cymbalta combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Cymbalta and Zanaflex combined.

Cymbalta and Zanaflex Combined have 33 Most Frequently Occurring Side Effects

Anxious - Anxiety is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Backache - Back Pain is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Blood Pressure Drop Upon Standing - Orthostatic Hypotension is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Depression is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Diarrhea is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Difficulty Speaking - Dysarthria is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Feeling Restless - Feeling Agitated is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Fever is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Inflammation of the Nose - Rhinitis is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Low Energy - Fatigue is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Muscle Weakness is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Nervous - Nervousness is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Numbness and Tingling - Paresthesia is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Rash - Skin Rash is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Skin Ulcer is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Urinary Tract Infection - Urinary Tract Infections is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Voluntary Movement Difficulty - Dyskinesia is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Weight Loss is a Frequently Occurring Side Effect of Cymbalta and Zanaflex combined

Click for a searchable interactive map of all Side Effects associated with Cymbalta and Zanaflex combined.

Cymbalta and Zanaflex Drug-Drug Interactions

There are no drug-drug interactions between Cymbalta and Zanaflex.

Cymbalta has 25 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Cymbalta.

Cymbalta Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Neuroleptic Malignant Syndrome is a contraindication of Cymbalta.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Cymbalta.

Relative Contraindications

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Cymbalta.

Alcoholic Liver Damage - Hardening of the Liver caused by Alcohol is a contraindication of Cymbalta.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Cymbalta.

Chronic Hepatitis - Chronic Inflammation of the Liver is a contraindication of Cymbalta.

Disease of Liver - Liver Problems is a contraindication of Cymbalta.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Cymbalta.

Hepatitis is a contraindication of Cymbalta.

Jaundice - Yellowing of Skin or Eyes from Liver Problems is a contraindication of Cymbalta.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Cymbalta.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Cymbalta.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Cymbalta.

Contraindication Warnings

Bipolar Disorder - Manic-Depression is a contraindication of Cymbalta.

Epilepsy - Epileptic Seizure is a contraindication of Cymbalta.

Gastrointestinal Hypomotility - Decreased Motility Function of Stomach or Intestines is a contraindication of Cymbalta.

Hyperglycemia - High Blood Sugar is a contraindication of Cymbalta.

Hypertension - High Blood Pressure is a contraindication of Cymbalta.

Hypomania - Mild Degree of Mania is a contraindication of Cymbalta.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Cymbalta.

Increased Risk of Bleeding is a contraindication of Cymbalta.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Cymbalta.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Cymbalta.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Cymbalta.

Urinary Retention - Cannot Empty Bladder is a contraindication of Cymbalta.

Zanaflex has 5 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zanaflex.

Zanaflex Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Hypotension - Abnormally Low Blood Pressure is a contraindication of Zanaflex.

Psychotic Disorder - Mental Disorder with Loss of Normal Personality & Reality is a contraindication of Zanaflex.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Zanaflex.

Contraindication Warnings

Bradycardia - Slow Heartbeat is a contraindication of Zanaflex.

Renal Disease - Kidney Disease is a contraindication of Zanaflex.

Cymbalta - Symptoms of overdose may include
severe drowsiness, fainting.

Zanaflex - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe drowsiness, fainting, trouble breathing, and unconsciousness.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.