Combine Depakote and Effexor

Drug Interactions and Combined Side Effects of
Depakote

and Effexor

Combine Depakote with Effexor. To make a decision about taking Depakote and Effexor, click here for a Medication Risk Map showing their individual and Combined Risks

Depakote and Effexor have 129 combined Side Effects total
66 are Life Threatening
32 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Depakote.
Click here for Drug Interactions and Side Effects of Effexor.
Click here to compare Depakote vs Effexor.

Uses of Depakote

Depakote is also known by the generic name Divalproex USES: This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

Uses of Effexor

Effexor is also known by the generic name Venlafaxine

USES:
Venlafaxine is used to treat depression. It may improve your mood and energy level, and may help restore your interest in daily living. Venlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

Depakote and Effexor Combined Have 66 Life Threatening (Major) Side Effects

Critcal Seriouosness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Abnormal Heart Electrical Signals - Abnormal ECG is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Blood Pressure Drop Upon Standing - Orthostatic Hypotension is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Blurred Vision is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Cannot Empty Bladder - Urinary Retention is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Chest Pain is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Decrease in the Ability of Platelet Cells to Clot - Platelet Aggregation Inhibition is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Depression is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Difficult or Painful Urination - Dysuria is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Disturbance in the Ability of the Eye to Focus - Accommodation Disorder is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Double Vision - Diplopia is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Enlarged Prostate - Benign Prostatic Hypertrophy is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Erythema Multiforme is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Feeling Restless - Feeling Agitated is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Frequent Urination - Increased Urinary Frequency is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Head Pain - Headache Disorder is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Hemorrhage of Blood Under the Skin - Ecchymosis is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - High Amount of Ammonium in the Blood - Hyperammonemia is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - High Cholesterol - Hypercholesterolemia is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Increased Risk of Bleeding is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Interstitial Pneumonitis is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Involuntary Eye Movement - Nystagmus is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Lockjaw - Trismus is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Loss of One's Own Sense of Reality or Identity - Depersonalization is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Low Blood Counts due to Bone Marrow Failure - Aplastic Anemia is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Low Body Temperature - Hypothermia is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Mental Impairment is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Mild Degree of Mania - Hypomania is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Pneumonia with High Amount of Eosinophil White Blood Cells - Eosinophilic Pneumonia is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Problem Behavior - Behavioral Disorders is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Problems with Eyesight - Visual Changes is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Ringing in the Ears - Tinnitus is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Seeing Spots - Visual Disturbance of Seeing Spots is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Sexual Problems - Abnormal Sexual Function is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Sinus Irritation and Congestion - Sinusitis is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Very Rapid Heartbeat - Torsades de Pointes - Torsades de Pointes is a Life Threatening Side Effect of Effexor and Depakote combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Effexor and Depakote combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Depakote and Effexor combined.

Depakote and Effexor Combined have 32 Most Frequently Occurring Side Effects

Anxious - Anxiety is a Frequently Occurring Side Effect of Depakote and Effexor combined

Blurred Vision is a Frequently Occurring Side Effect of Depakote and Effexor combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Depakote and Effexor combined

Diarrhea is a Frequently Occurring Side Effect of Depakote and Effexor combined

Disturbance in the Ability of the Eye to Focus - Accommodation Disorder is a Frequently Occurring Side Effect of Depakote and Effexor combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Depakote and Effexor combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Depakote and Effexor combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Depakote and Effexor combined

Easily Angered or Annoyed - Irritability is a Frequently Occurring Side Effect of Depakote and Effexor combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Depakote and Effexor combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Depakote and Effexor combined

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Depakote and Effexor combined

Hair Loss - Alopecia is a Frequently Occurring Side Effect of Depakote and Effexor combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Depakote and Effexor combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Depakote and Effexor combined

Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Depakote and Effexor combined

Infection is a Frequently Occurring Side Effect of Depakote and Effexor combined

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Depakote and Effexor combined

Irregular Periods - Irregular Menstrual Periods is a Frequently Occurring Side Effect of Depakote and Effexor combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Depakote and Effexor combined

Nervous - Nervousness is a Frequently Occurring Side Effect of Depakote and Effexor combined

Numbness and Tingling - Paresthesia is a Frequently Occurring Side Effect of Depakote and Effexor combined

Problem with Ejaculation - Disorder of Ejaculation is a Frequently Occurring Side Effect of Depakote and Effexor combined

Problems with Eyesight - Visual Changes is a Frequently Occurring Side Effect of Depakote and Effexor combined

Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Depakote and Effexor combined

Sexual Problems - Abnormal Sexual Function is a Frequently Occurring Side Effect of Depakote and Effexor combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Depakote and Effexor combined

Taste Problems - Dysgeusia is a Frequently Occurring Side Effect of Depakote and Effexor combined

Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Depakote and Effexor combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Depakote and Effexor combined

Weight Gain is a Frequently Occurring Side Effect of Depakote and Effexor combined

Weight Loss is a Frequently Occurring Side Effect of Depakote and Effexor combined

Click for a searchable interactive map of all Side Effects associated with Depakote and Effexor combined.

Depakote and Effexor Drug-Drug Interactions

There are no drug-drug interactions between Depakote and Effexor.

Depakote has 16 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Depakote.

Depakote Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Depakote.

Carbamyl Phosphate Synthetase Deficiency - Inherited Deficiency of Carbamyl Phosphate Synthetase is a contraindication of Depakote.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Depakote.

Disease of Liver - Liver Problems is a contraindication of Depakote.

Ornithine Carbamyltransferase Deficiency is a contraindication of Depakote.

Pregnancy is a contraindication of Depakote.

Relative Contraindications

Hyperammonemia - High Amount of Ammonium in the Blood is a contraindication of Depakote.

Porphyria is a contraindication of Depakote.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Depakote.

Contraindication Warnings

Blood Dyscrasias - Blood Disorder is a contraindication of Depakote.

Depression is a contraindication of Depakote.

Hypoalbuminemia - Low Amount of Albumin Proteins in the Blood is a contraindication of Depakote.

Organic Mental Disorder - Dysfunction of the Brain is a contraindication of Depakote.

Renal Disease - Kidney Disease is a contraindication of Depakote.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Depakote.

Valproic Acid Toxicity - Poisoning by Drug Valproic Acid is a contraindication of Depakote.

Effexor has 28 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Effexor.

Effexor Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Effexor.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Effexor.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Effexor.

Ocular Hypertension - Increased Pressure in the Eye is a contraindication of Effexor.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Effexor.

Recovery Phase Following Myocardial Infarct - Recent Heart Attack is a contraindication of Effexor.

Renal Disease with Mild to Moderate Renal Function Impairment - Mild to Moderate Kidney Impairment is a contraindication of Effexor.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Effexor.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Effexor.

Severe Uncontrolled Hypertension - Severe Uncontrolled High Blood Pressure is a contraindication of Effexor.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Effexor.

Upper GI Bleed - Bleeding from Stomach, Esophagus or Duodenum is a contraindication of Effexor.

Contraindication Warnings

Blood Coagulation Disorder - Blood Clotting Disorder is a contraindication of Effexor.

Chronic Heart Failure is a contraindication of Effexor.

Drug Dependence - Taking Habit Forming Drugs is a contraindication of Effexor.

Hypercholesterolemia - High Cholesterol is a contraindication of Effexor.

Hypertension - High Blood Pressure is a contraindication of Effexor.

Hyperthyroidism - Overactive Thyroid Gland is a contraindication of Effexor.

Hypomania - Mild Degree of Mania is a contraindication of Effexor.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Effexor.

Increased Risk of Bleeding is a contraindication of Effexor.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Effexor.

Neuroleptic Malignant Syndrome is a contraindication of Effexor.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Effexor.

Seizure Disorder - Seizures is a contraindication of Effexor.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Effexor.

Substance Abuse - Misuse or Excessive Use of Drugs is a contraindication of Effexor.

Weight Loss is a contraindication of Effexor.

Depakote - Symptoms of overdose may include
excessive drowsiness, coma, irregular/slowed/skipped heart beats (heart block).

Effexor - Symptoms of overdose may include
severe drowsiness, seizures, fast/irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.