Combine Depakote and Migraine

Drug Interactions and Combined Side Effects of
Depakote

and Migraine

Combine Depakote with Migraine. To make a decision about taking Depakote and Migraine, click here for a Medication Risk Map showing their individual and Combined Risks

Depakote and Migraine have 89 combined Side Effects total
47 are Life Threatening
21 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Depakote.
Click here for Drug Interactions and Side Effects of Migraine.
Click here to compare Depakote vs Migraine.

Uses of Depakote

Depakote is also known by the generic name Divalproex USES: This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

Uses of Migraine

Migraine is also known by the generic name Acetaminophn-Isometh-Dichloral

Migraine is also known by the generic name Aspirin-Acetaminophen-Caffeine

USES:
This combination medication is used to relieve tension and migraine headaches. Acetaminophen helps to decrease the pain from the headache. Isometheptene helps to narrow the widened blood vessels in the head. Headache pain can be caused by these widened blood vessels. Dichloralphenazone helps to relax the body.

Depakote and Migraine Combined Have 47 Life Threatening (Major) Side Effects

Critcal Seriouosness - A Rupture in the Wall of the Stomach or Intestine - Gastrointestinal Perforation is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Anemia is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Blood coming from Anus - Rectal Bleeding is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Decrease in the Ability of Platelet Cells to Clot - Platelet Aggregation Inhibition is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Double Vision - Diplopia is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Drowsiness - Drowsy is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Extra Heartbeat - Extrasystoles is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Hemolytic Anemia is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Hemorrhage Within the Skull - Intracranial Bleeding is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - High Amount of Ammonium in the Blood - Hyperammonemia is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Interstitial Nephritis is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Involuntary Eye Movement - Nystagmus is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Large Purple or Brown Skin Blotches - Purpura is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Low Body Temperature - Hypothermia is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Mental Impairment is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Problem Behavior - Behavioral Disorders is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Redness of Skin - Erythema is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Ringing in the Ears - Tinnitus is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Seeing Spots - Visual Disturbance of Seeing Spots is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Stomach or Intestinal Ulcer - Gastrointestinal Ulcer is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Wheezing is a Life Threatening Side Effect of Migraine and Depakote combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Migraine and Depakote combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Depakote and Migraine combined.

Depakote and Migraine Combined have 21 Most Frequently Occurring Side Effects

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Depakote and Migraine combined

Conditions of Excess Stomach Acid Secretion - Gastric Hypersecretory Conditions is a Frequently Occurring Side Effect of Depakote and Migraine combined

Diarrhea is a Frequently Occurring Side Effect of Depakote and Migraine combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Depakote and Migraine combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Depakote and Migraine combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Depakote and Migraine combined

Hair Loss - Alopecia is a Frequently Occurring Side Effect of Depakote and Migraine combined

Heartburn is a Frequently Occurring Side Effect of Depakote and Migraine combined

Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Depakote and Migraine combined

Infection is a Frequently Occurring Side Effect of Depakote and Migraine combined

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Depakote and Migraine combined

Irregular Periods - Irregular Menstrual Periods is a Frequently Occurring Side Effect of Depakote and Migraine combined

Irritation of the Stomach or Intestines - Gastrointestinal Irritation is a Frequently Occurring Side Effect of Depakote and Migraine combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Depakote and Migraine combined

Nervous - Nervousness is a Frequently Occurring Side Effect of Depakote and Migraine combined

Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Depakote and Migraine combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Depakote and Migraine combined

Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Depakote and Migraine combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Depakote and Migraine combined

Weight Gain is a Frequently Occurring Side Effect of Depakote and Migraine combined

Weight Loss is a Frequently Occurring Side Effect of Depakote and Migraine combined

Click for a searchable interactive map of all Side Effects associated with Depakote and Migraine combined.

Depakote and Migraine Drug-Drug Interactions

When combined Depakote and Migraine have the following 1 Drug-Drug Interaction(s): When combined Depakote and Migraine have the following interaction of Moderate seriousness: Concurrent use of salicylates may increase the unbound fraction of serum valproic acid concentration, resulting in toxicity. Click for a searchable interactive map of all interactions between Depakote and Migraine.

Depakote has 16 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Depakote.

Depakote Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Depakote.

Carbamyl Phosphate Synthetase Deficiency - Inherited Deficiency of Carbamyl Phosphate Synthetase is a contraindication of Depakote.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Depakote.

Disease of Liver - Liver Problems is a contraindication of Depakote.

Ornithine Carbamyltransferase Deficiency is a contraindication of Depakote.

Pregnancy is a contraindication of Depakote.

Relative Contraindications

Hyperammonemia - High Amount of Ammonium in the Blood is a contraindication of Depakote.

Porphyria is a contraindication of Depakote.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Depakote.

Contraindication Warnings

Blood Dyscrasias - Blood Disorder is a contraindication of Depakote.

Depression is a contraindication of Depakote.

Hypoalbuminemia - Low Amount of Albumin Proteins in the Blood is a contraindication of Depakote.

Organic Mental Disorder - Dysfunction of the Brain is a contraindication of Depakote.

Renal Disease - Kidney Disease is a contraindication of Depakote.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Depakote.

Valproic Acid Toxicity - Poisoning by Drug Valproic Acid is a contraindication of Depakote.

Migraine has 36 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Migraine.

Migraine Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acetaminophen Toxicity - Overdose of the Drug Acetaminophen is a contraindication of Migraine.

Gastrointestinal Hemorrhage - Bleeding of the Stomach or Intestines is a contraindication of Migraine.

Hemolytic Anemia from Pyruvate Kinase and G6PD Deficiencies - Anemia from Pyruvate Kinase and G6PD Deficiencies is a contraindication of Migraine.

Hemophilia is a contraindication of Migraine.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Migraine.

Peptic Ulcer - Ulcer from Stomach Acid is a contraindication of Migraine.

Pregnancy is a contraindication of Migraine.

Recovery Phase Following Myocardial Infarct - Recent Heart Attack is a contraindication of Migraine.

Reye's Syndrome is a contraindication of Migraine.

Von Willebrand's Disease - Blood Clotting Disorder - Von Willebrand's Disease is a contraindication of Migraine.

Relative Contraindications

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Migraine.

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Migraine.

Disease of Liver - Liver Problems is a contraindication of Migraine.

Erosive Gastritis - Damage to Stomach Lining is a contraindication of Migraine.

Gastrointestinal Ulcer - Stomach or Intestinal Ulcer is a contraindication of Migraine.

Gout is a contraindication of Migraine.

Hypoprothrombinemia - Decrease in the Blood-Clotting Protein Prothrombin is a contraindication of Migraine.

Insomnia - Chronic Trouble Sleeping is a contraindication of Migraine.

Myocardial Ischemia - Disease of Inadequate Blood Flow to the Heart Muscle is a contraindication of Migraine.

Necrotizing Enterocolitis - Inflamed Colon and Small Intestine with Some Tissue Death is a contraindication of Migraine.

Peptic Ulcer - Ulcer from Stomach Acid is a contraindication of Migraine.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Migraine.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Migraine.

Thrombotic Thrombocytopenic Purpura is a contraindication of Migraine.

Contraindication Warnings

Agoraphobia - Fear of Leaving One's Home is a contraindication of Migraine.

Anemia is a contraindication of Migraine.

Disease of Liver - Liver Problems is a contraindication of Migraine.

Hypertension - High Blood Pressure is a contraindication of Migraine.

Nasal Polyp - Presence of Polyps in the Nose is a contraindication of Migraine.

Obsessive-Compulsive Disorder - Obsessive Compulsive Disorder is a contraindication of Migraine.

Panic Disorder is a contraindication of Migraine.

Renal Disease - Kidney Disease is a contraindication of Migraine.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Migraine.

Seizure Disorder - Seizures is a contraindication of Migraine.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Migraine.

Vitamin K Deficiency - Inadequate Vitamin K is a contraindication of Migraine.

Depakote - Symptoms of overdose may include
excessive drowsiness, coma, irregular/slowed/skipped heart beats (heart block).

Migraine - Symptoms of overdose may include
restlessness, severe drowsiness/dizziness, low body temperature, fast/slow breathing, fast/slow/irregular heartbeat, unresponsiveness.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.