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Uses of Depakote
 
Depakote is also known by the generic name Divalproex


USES:
This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.


Uses of Valproic Acid
 
USES:
This medication is used to treat seizure disorders, mental/mood conditions (such as manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.


Depakote and Valproic Acid Combined Have 20 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Decrease in the Ability of Platelet Cells to Clot - Platelet Aggregation Inhibition is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Double Vision - Diplopia is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - High Amount of Ammonium in the Blood - Hyperammonemia is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Involuntary Eye Movement - Nystagmus is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Low Body Temperature - Hypothermia is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Mental Impairment is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Problem Behavior - Behavioral Disorders is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Seeing Spots - Visual Disturbance of Seeing Spots is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Valproic Acid and Depakote combined
Critcal Seriouosness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Valproic Acid and Depakote combined

Depakote and Valproic Acid Combined have 27 Most Frequently Occurring Side Effects
 
Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Depression is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Diarrhea is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Dizzy - Dizziness is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Drowsiness - Drowsy is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Easily Angered or Annoyed - Irritability is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Fever is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Flu-Like Symptoms is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Hair Loss - Alopecia is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Infection is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Irregular Periods - Irregular Menstrual Periods is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Nervous - Nervousness is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Unsteady Walking - Unsteady Gait is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Voluntary Movement Difficulty - Dyskinesia is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Weight Gain is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined
Weight Loss is a Frequently Occurring Side Effect of Depakote and Valproic Acid combined

Depakote and Valproic Acid Drug-Drug Interactions
 
There are no drug-drug interactions between Depakote and Valproic Acid.

Depakote has 16 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Depakote.

Depakote Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Depakote.

Carbamyl Phosphate Synthetase Deficiency - Inherited Deficiency of Carbamyl Phosphate Synthetase is a contraindication of Depakote.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Depakote.

Disease of Liver - Liver Problems is a contraindication of Depakote.

Ornithine Carbamyltransferase Deficiency is a contraindication of Depakote.

Pregnancy is a contraindication of Depakote.

Relative Contraindications 

Hyperammonemia - High Amount of Ammonium in the Blood is a contraindication of Depakote.

Porphyria is a contraindication of Depakote.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Depakote.

Contraindication Warnings 

Blood Dyscrasias - Blood Disorder is a contraindication of Depakote.

Depression is a contraindication of Depakote.

Hypoalbuminemia - Low Amount of Albumin Proteins in the Blood is a contraindication of Depakote.

Organic Mental Disorder - Dysfunction of the Brain is a contraindication of Depakote.

Renal Disease - Kidney Disease is a contraindication of Depakote.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Depakote.

Valproic Acid Toxicity - Poisoning by Drug Valproic Acid is a contraindication of Depakote.

Valproic Acid has 20 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Valproic Acid.

Valproic Acid Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Valproic Acid.

Arginase Deficiency is a contraindication of Valproic Acid.

Arginosuccinate Lyase Deficiency - Inherited Deficiency of Arginosuccinate Lyase is a contraindication of Valproic Acid.

Carbamyl Phosphate Synthetase Deficiency - Inherited Deficiency of Carbamyl Phosphate Synthetase is a contraindication of Valproic Acid.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Valproic Acid.

Citrullinemia is a contraindication of Valproic Acid.

Disease of Liver - Liver Problems is a contraindication of Valproic Acid.

Ornithine Carbamyltransferase Deficiency is a contraindication of Valproic Acid.

Pregnancy is a contraindication of Valproic Acid.

Valproic Acid Toxicity - Poisoning by Drug Valproic Acid is a contraindication of Valproic Acid.

Relative Contraindications 

Hyperammonemia - High Amount of Ammonium in the Blood is a contraindication of Valproic Acid.

Hypothermia - Low Body Temperature is a contraindication of Valproic Acid.

Porphyria is a contraindication of Valproic Acid.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Valproic Acid.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Valproic Acid.

Contraindication Warnings 

Blood Dyscrasias - Blood Disorder is a contraindication of Valproic Acid.

Depression is a contraindication of Valproic Acid.

Hypoalbuminemia - Low Amount of Albumin Proteins in the Blood is a contraindication of Valproic Acid.

Organic Mental Disorder - Dysfunction of the Brain is a contraindication of Valproic Acid.

Renal Disease - Kidney Disease is a contraindication of Valproic Acid.
Depakote - Symptoms of overdose may include
excessive drowsiness, coma, irregular/slowed/skipped heart beats (heart block).

Valproic Acid - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include excessive drowsiness, coma, irregular/slowed/skipped heart beats (heart block).

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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