Combine Depakote and Wellbutrin

Drug Interactions and Combined Side Effects of
Depakote

and Wellbutrin

Combine Depakote with Wellbutrin. To make a decision about taking Depakote and Wellbutrin, click here for a Medication Risk Map showing their individual and Combined Risks

Depakote and Wellbutrin have 86 combined Side Effects total
42 are Life Threatening
22 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Depakote.
Click here for Drug Interactions and Side Effects of Wellbutrin.
Click here to compare Depakote vs Wellbutrin.

Uses of Depakote

Depakote is also known by the generic name Divalproex USES: This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

Uses of Wellbutrin

Wellbutrin is also known by the generic name Bupropion Hcl USES: Bupropion is used to treat depression. It can improve your mood and feelings of well-being. It may work by helping to restore the balance of certain natural chemicals (neurotransmitters) in your brain.

Depakote and Wellbutrin Combined Have 42 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Anxious - Anxiety is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Cannot Focus Thoughts - Concentration Difficulty is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Chest Pain is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Decrease in the Ability of Platelet Cells to Clot - Platelet Aggregation Inhibition is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Delusions - Delusional Disorder is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Double Vision - Diplopia is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Feeling Restless - Feeling Agitated is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - High Amount of Ammonium in the Blood - Hyperammonemia is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Involuntary Eye Movement - Nystagmus is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Joint Pain - Arthralgia is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Low Body Temperature - Hypothermia is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Mental Disorder with Loss of Normal Personality & Reality - Psychotic Disorder is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Mental Impairment is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Painful Periods - Dysmenorrhea is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Paranoia - Paranoid Disorder is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Problem Behavior - Behavioral Disorders is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Ringing in the Ears - Tinnitus is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Seeing Spots - Visual Disturbance of Seeing Spots is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Severe Headache - Severe Headache Disorder is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Suicidal is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Thoughts of Hurting or Killing Others - Homicidal Ideation is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Wellbutrin and Depakote combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Depakote and Wellbutrin combined.

Depakote and Wellbutrin Combined have 22 Most Frequently Occurring Side Effects

Anxious - Anxiety is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Diarrhea is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Feeling Restless - Feeling Agitated is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Hair Loss - Alopecia is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Infection is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Irregular Periods - Irregular Menstrual Periods is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Weight Gain is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Weight Loss is a Frequently Occurring Side Effect of Depakote and Wellbutrin combined

Click for a searchable interactive map of all Side Effects associated with Depakote and Wellbutrin combined.

Depakote and Wellbutrin Drug-Drug Interactions

There are no drug-drug interactions between Depakote and Wellbutrin.

Depakote has 16 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Depakote.

Depakote Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Depakote.

Carbamyl Phosphate Synthetase Deficiency - Inherited Deficiency of Carbamyl Phosphate Synthetase is a contraindication of Depakote.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Depakote.

Disease of Liver - Liver Problems is a contraindication of Depakote.

Ornithine Carbamyltransferase Deficiency is a contraindication of Depakote.

Pregnancy is a contraindication of Depakote.

Relative Contraindications

Hyperammonemia - High Amount of Ammonium in the Blood is a contraindication of Depakote.

Porphyria is a contraindication of Depakote.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Depakote.

Contraindication Warnings

Blood Dyscrasias - Blood Disorder is a contraindication of Depakote.

Depression is a contraindication of Depakote.

Hypoalbuminemia - Low Amount of Albumin Proteins in the Blood is a contraindication of Depakote.

Organic Mental Disorder - Dysfunction of the Brain is a contraindication of Depakote.

Renal Disease - Kidney Disease is a contraindication of Depakote.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Depakote.

Valproic Acid Toxicity - Poisoning by Drug Valproic Acid is a contraindication of Depakote.

Wellbutrin has 28 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Wellbutrin.

Wellbutrin Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Anorexia Nervosa is a contraindication of Wellbutrin.

Bulimia Nervosa - Bulimia is a contraindication of Wellbutrin.

Seizure Disorder - Seizures is a contraindication of Wellbutrin.

Seizure due to Abrupt Benzodiazepine Withdrawal - Seizure caused by Sudden Withdrawal of Benzodiazepine is a contraindication of Wellbutrin.

Seizure due to Alcohol Withdrawal - Seizure caused by Stopping Alcohol Use is a contraindication of Wellbutrin.

Relative Contraindications

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Wellbutrin.

Central Nervous System Neoplasm - Tumor of the Brain or Spinal Cord is a contraindication of Wellbutrin.

Cerebral Metastases - Spread of Cancer to the Brain is a contraindication of Wellbutrin.

Feeling Agitated - Feeling Restless is a contraindication of Wellbutrin.

Head Injury is a contraindication of Wellbutrin.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Wellbutrin.

Hostility - Feeling Anger Toward Something is a contraindication of Wellbutrin.

Lower Seizure Threshold is a contraindication of Wellbutrin.

Manic Bipolar Disorder - Manic Phase of Manic-Depression is a contraindication of Wellbutrin.

Mood Changes is a contraindication of Wellbutrin.

Opioid Dependence - Narcotic Addiction is a contraindication of Wellbutrin.

Panic Disorder is a contraindication of Wellbutrin.

Renal Disease - Kidney Disease is a contraindication of Wellbutrin.

Sedative Drug Dependence is a contraindication of Wellbutrin.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Wellbutrin.

Stimulant Drug Dependence is a contraindication of Wellbutrin.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Wellbutrin.

Uncontrolled Diabetes Mellitus - Diabetes that is Not Under Control is a contraindication of Wellbutrin.

Contraindication Warnings

Disease of Liver - Liver Problems is a contraindication of Wellbutrin.

Hypertension - High Blood Pressure is a contraindication of Wellbutrin.

Myocardial Infarction - Heart Attack is a contraindication of Wellbutrin.

Psychotic Disorder - Mental Disorder with Loss of Normal Personality & Reality is a contraindication of Wellbutrin.

Weight Loss is a contraindication of Wellbutrin.

Depakote - Symptoms of overdose may include
excessive drowsiness, coma, irregular/slowed/skipped heart beats (heart block).

Wellbutrin - Symptoms of overdose may include
seizures, hallucinations, fast or slow heart rate, loss of consciousness.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.