Combine Enbrel and Raptiva

Drug Interactions and Combined Side Effects of
Enbrel

and Raptiva

Combine Enbrel with Raptiva. To make a decision about taking Enbrel and Raptiva, click here for a Medication Risk Map showing their individual and Combined Risks

Enbrel and Raptiva have 100 combined Side Effects total
62 are Life Threatening
15 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Enbrel.
Click here for Drug Interactions and Side Effects of Raptiva.
Click here to compare Enbrel vs Raptiva.

Uses of Enbrel

Enbrel is also known by the generic name Etanercept

USES:
This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis), as well as a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin.

Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life.

This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.

Uses of Raptiva

Raptiva is also known by the generic name Efalizumab

USES:
This medication is used to treat adults with moderate to severe plaque psoriasis. Discuss risks and benefits of treatment and other possible medication options with your doctor.

This drug is a man-made protein (monoclonal antibody) that decreases the actions of certain immune system cells (T lymphocytes). This action decreases the skin changes that are seen with plaque psoriasis.

This drug has been withdrawn from the US and Canadian markets due to problems with safety (see Warning section - PML). Talk with your doctor about alternative treatments for psoriasis.

Enbrel and Raptiva Combined Have 62 Life Threatening (Major) Side Effects

Critcal Seriouosness - A Fungal Infection - Aspergillosis - Aspergillosis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Abscess Within the Abdomen - Intra-Abdominal Abscess is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Abscess is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Acquired Decrease of All Cells in the Blood - Pancytopenia is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Active Tuberculosis - Acute Tuberculosis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Anemia is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Bacteria causing an Infection in the Joints - Septic Arthritis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Bacterial Infection of Blood or Tissues affecting the Whole Body - Bacterial Septicemia is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Bacterial Infection of the Kidney and Renal Pelvis - Pyelonephritis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Bronchitis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Chickenpox is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Chronic Heart Failure is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Drug Therapy that Worsens or Flares Psoriasis - Drug-Exacerbated Psoriasis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Generalized Disorder of Peripheral Nerves - Polyneuropathies is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Guillain-Barre Syndrome is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Hemolytic Anemia is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Infection caused by Blastomyces Dermatitidis Fungus - Blastomycosis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Infection caused by Coccidioides Fungus - Coccidioidomycosis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Infection caused by a Fungus - Fungal Infections is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Infection due to the Candida Fungus - Candidiasis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Infection is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Inflamed Spinal Cord - Myelitis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Inflammation of the Gallbladder - Cholecystitis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Inflammation of the Lining of the Stomach and Intestines - Gastroenteritis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Inflammation of the Salivary Glands - Sialoadenitis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Interstitial Pneumonitis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Legionnaire's Disease - Legionnaires' Disease is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Leukemia is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Liver Inflammation caused by Body's Own Immune Response - Autoimmune Hepatitis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Low Blood Counts due to Bone Marrow Failure - Aplastic Anemia is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Lupus-Like Syndrome is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Malignant Lymphoma is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Malignant Tumor or Cancer - Malignancy is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Meningitis Not Caused by an Infection - Non-Infective Meningitis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Multiple Sclerosis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Pneumonia caused by Mycoplasma Pneumoniae - Mycoplasmal Pneumonia is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Pneumonia is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Progressive Disease in the White Matter of the Brain - Progressive Multifocal Leukoencephalopathy is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Reactivated Tuberculosis - Reactivation Tuberculosis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Relapse of Hepatitis B Infection Symptoms - Reactivation Hepatitis B is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Serious Skin Infection due to Streptococcus Bacteria - Necrotizing Fasciitis Streptococcus Infection is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Severe Infection is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Sinus Irritation and Congestion - Sinusitis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Sudden Blindness and Pain Upon Moving the Eye - Optic Neuritis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Throwing Up - Vomiting is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Type of Infection caused by Histoplasmosis Fungus - Histoplasmosis is a Life Threatening Side Effect of Raptiva and Enbrel combined

Critcal Seriouosness - Worsening of Chronic Heart Failure is a Life Threatening Side Effect of Raptiva and Enbrel combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Enbrel and Raptiva combined.

Enbrel and Raptiva Combined have 15 Most Frequently Occurring Side Effects

Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Chickenpox is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Chills is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Fever is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Flu-Like Symptoms is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Infection is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Inflammation of the Nose - Rhinitis is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Muscle Pain - Myalgia is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Signs and Symptoms at Injection Site - Injection Site Sequelae is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Sinus Irritation and Congestion - Sinusitis is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Enbrel and Raptiva combined

Click for a searchable interactive map of all Side Effects associated with Enbrel and Raptiva combined.

Enbrel and Raptiva Drug-Drug Interactions

When combined Enbrel and Raptiva have the following 1 Drug-Drug Interaction(s):

When combined Enbrel and Raptiva have the following interaction of Severe seriousness: Concurrent use of natalizumab or efalizumab with immunosuppressives or immunomodulators may result in an increased risk of infections, including progressive multifocal leukoencephalopathy.

Click for a searchable interactive map of all interactions between Enbrel and Raptiva.

Enbrel has 40 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Enbrel.

Enbrel Subcutaneous Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Decompensated Heart Failure - Suddenly Serious Symptoms of Heart Failure is a contraindication of Enbrel.

Acute Tuberculosis - Active Tuberculosis is a contraindication of Enbrel.

Aplastic Anemia - Low Blood Counts due to Bone Marrow Failure is a contraindication of Enbrel.

Aspergillosis - A Fungal Infection - Aspergillosis is a contraindication of Enbrel.

Autoimmune Hepatitis - Liver Inflammation caused by Body's Own Immune Response is a contraindication of Enbrel.

Blastomycosis - Infection caused by Blastomyces Dermatitidis Fungus is a contraindication of Enbrel.

Coccidioidomycosis - Infection caused by Coccidioides Fungus is a contraindication of Enbrel.

Demyelination - Demyelinating Disease is a contraindication of Enbrel.

Disseminated Candidiasis - Candidiasis Yeast Infection that Spreads Throughout Body is a contraindication of Enbrel.

Histoplasmosis - Type of Infection caused by Histoplasmosis Fungus is a contraindication of Enbrel.

Leukemia is a contraindication of Enbrel.

Lupus-Like Syndrome is a contraindication of Enbrel.

Malignancy - Malignant Tumor or Cancer is a contraindication of Enbrel.

Malignant Lymphoma is a contraindication of Enbrel.

Miliary Tuberculosis - Tuberculosis of Lungs which Spreads to Other Body Parts is a contraindication of Enbrel.

Opportunistic Fungal Infection - A Fungal Infection that Occurs Under Certain Circumstances is a contraindication of Enbrel.

Pneumocystis Carinii Pneumonia - Pneumonia caused by Pneumocystis Carinii is a contraindication of Enbrel.

Reactivation Hepatitis B - Relapse of Hepatitis B Infection Symptoms is a contraindication of Enbrel.

Reactivation Tuberculosis - Reactivated Tuberculosis is a contraindication of Enbrel.

Sepsis Syndrome is a contraindication of Enbrel.

Severe Infection is a contraindication of Enbrel.

Relative Contraindications

Alcoholic Liver Damage - Hardening of the Liver caused by Alcohol is a contraindication of Enbrel.

Blood Dyscrasias - Blood Disorder is a contraindication of Enbrel.

Candidiasis - Infection due to the Candida Fungus is a contraindication of Enbrel.

Chronic Heart Failure is a contraindication of Enbrel.

Chronic Infection - Infection that Lasts a Long Time is a contraindication of Enbrel.

Chronic Type B Viral Hepatitis - Chronic Hepatitis B is a contraindication of Enbrel.

Hepatitis B Immune due to Latent Hepatitis B Infection - Resolved Hepatitis B is a contraindication of Enbrel.

Immunosuppression - Reduction in the Body's Resistance to Infection is a contraindication of Enbrel.

Inactive Tuberculosis is a contraindication of Enbrel.

Multiple Sclerosis is a contraindication of Enbrel.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Enbrel.

Optic Neuritis - Sudden Blindness and Pain Upon Moving the Eye is a contraindication of Enbrel.

Pancytopenia - Acquired Decrease of All Cells in the Blood is a contraindication of Enbrel.

Seizure Disorder - Seizures is a contraindication of Enbrel.

Severe Diabetes Mellitus - Severe Form of Diabetes is a contraindication of Enbrel.

Uncontrolled Diabetes Mellitus - Diabetes that is Not Under Control is a contraindication of Enbrel.

Viral Hepatitis B - Hepatitis B is a contraindication of Enbrel.

Viral Infection - Infection caused by a Virus is a contraindication of Enbrel.

Contraindication Warnings

Oral Cavity Disorders - Problem with Mouth, Teeth, Jaw or Pharynx is a contraindication of Enbrel.

Raptiva has 18 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Raptiva.

Raptiva Subcutaneous Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Bacterial Septicemia - Bacterial Infection of Blood or Tissues affecting the Whole Body is a contraindication of Raptiva.

Leukemia is a contraindication of Raptiva.

Progressive Multifocal Leukoencephalopathy - Progressive Disease in the White Matter of the Brain is a contraindication of Raptiva.

Relative Contraindications

Autoimmune Thrombocytopenia - Immune Reaction Causing Low Platelet Count is a contraindication of Raptiva.

Chronic Infection - Infection that Lasts a Long Time is a contraindication of Raptiva.

Fungal Infections - Infection caused by a Fungus is a contraindication of Raptiva.

HIV Infection - HIV is a contraindication of Raptiva.

Hemolytic Anemia is a contraindication of Raptiva.

Herpes Zoster - Shingles is a contraindication of Raptiva.

Immunosuppression - Reduction in the Body's Resistance to Infection is a contraindication of Raptiva.

Inactive Tuberculosis is a contraindication of Raptiva.

Latent Syphilis - Inactive Syphilis is a contraindication of Raptiva.

Malignancy - Malignant Tumor or Cancer is a contraindication of Raptiva.

Malignant Lymphoma is a contraindication of Raptiva.

Severe Infection is a contraindication of Raptiva.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Raptiva.

Contraindication Warnings

Arthritis is a contraindication of Raptiva.

Neuropathy - Disease of the Nerves is a contraindication of Raptiva.

Enbrel - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canada residents should call their local poison control center directly.

Raptiva - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe vomiting.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.