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Uses of Januvia
 
Januvia is also known by the generic name Sitagliptin


USES:
Sitagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in people with type 2 (non-insulin-dependent) diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

Sitagliptin is an anti-diabetic drug that works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes.

This medication should not be used to treat people with type 1 diabetes (insulin-dependent diabetes).


Uses of Amaryl
 
Amaryl is also known by the generic name Glimepiride


USES:
Glimepiride is an anti-diabetic drug (sulfonylurea-type) used along with a proper diet and exercise program to control high blood sugar. It is used in patients with type 2 diabetes (non-insulin-dependent diabetes). It works by stimulating the release of your body's natural insulin. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.


Januvia and Amaryl Combined Have 28 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Acquired Decrease of All Cells in the Blood - Pancytopenia is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Blurred Vision is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Discolored Spots and Small Elevations of the Skin - Maculopapular Rash is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Hemolytic Anemia is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Inflammation of Blood Vessels in the Skin - Cutaneous Vasculitis is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Liver Problems - Disease of Liver is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Low Blood Counts due to Bone Marrow Failure - Aplastic Anemia is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Porphyria Cutanea Tarda is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Redness of Skin - Erythema is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Syndrome of Inappropriate Antidiuretic Hormone Secretion - SIADH Syndrome is a Life Threatening Side Effect of Amaryl and Januvia combined
Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Amaryl and Januvia combined

Januvia and Amaryl Combined have 0 Most Frequently Occurring Side Effects
 

Januvia and Amaryl Drug-Drug Interactions
 
There are no drug-drug interactions between Januvia and Amaryl.

Januvia has 6 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Januvia.

Januvia Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Januvia.

Relative Contraindications 

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Januvia.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Januvia.

Contraindication Warnings 

High Fever >101 Degrees Fahrenheit - Body Temperature More Than 101 Degrees F is a contraindication of Januvia.

Surgical Procedure - Recent Operation is a contraindication of Januvia.

Trauma - Injury is a contraindication of Januvia.

Amaryl has 15 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Amaryl.

Amaryl Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Amaryl.

Relative Contraindications 

Hepatic Porphyria is a contraindication of Amaryl.

Contraindication Warnings 

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Amaryl.

Autonomic Dysreflexia - Dysreflexia is a contraindication of Amaryl.

Debilitation - Weakened Patient is a contraindication of Amaryl.

Disease of Liver - Liver Problems is a contraindication of Amaryl.

G6PD Deficiency Anemia - G6PD Anemia is a contraindication of Amaryl.

Hemolytic Anemia is a contraindication of Amaryl.

High Fever >101 Degrees Fahrenheit - Body Temperature More Than 101 Degrees F is a contraindication of Amaryl.

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Amaryl.

Pituitary Insufficiency - Pituitary Hormone Deficiency is a contraindication of Amaryl.

Primary Adrenocortical Insufficiency - Addison's Disease is a contraindication of Amaryl.

Renal Disease - Kidney Disease is a contraindication of Amaryl.

Surgical Procedure - Recent Operation is a contraindication of Amaryl.

Trauma - Injury is a contraindication of Amaryl.
Januvia - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Amaryl - Symptoms of overdose may include
shakiness, rapid heartbeat, unexplained sweating, loss of consciousness.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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