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Uses of Januvia
 
Januvia is also known by the generic name Sitagliptin


USES:
Sitagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in people with type 2 (non-insulin-dependent) diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

Sitagliptin is an anti-diabetic drug that works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes.

This medication should not be used to treat people with type 1 diabetes (insulin-dependent diabetes).


Uses of Glipizide
 
USES:
Glipizide is an anti-diabetic drug (sulfonylurea-type) used along with a proper diet and exercise program to control high blood sugar. It is used in patients with type 2 diabetes (non-insulin-dependent diabetes). It works by stimulating the release of your body's natural insulin. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.


Januvia and Glipizide Combined Have 28 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - Acquired Decrease of All Cells in the Blood - Pancytopenia is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Blockage of Normal Bile Flow - Cholestasis is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Blood Disorder - Blood Dyscrasias is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Erythema Multiforme is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Excess Urination - Polyuria is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Hemolytic Anemia is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Hepatic Porphyria is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Increased Eosinophils in the Blood - Eosinophilia is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Inflammation of Blood Vessels in the Skin - Cutaneous Vasculitis is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Liver Failure - Hepatic Failure is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Liver Problems - Disease of Liver is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Low Blood Counts due to Bone Marrow Failure - Aplastic Anemia is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Porphyria Cutanea Tarda is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Skin Rash with Sloughing - Exfoliative Dermatitis is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Weight Gain is a Life Threatening Side Effect of Glipizide and Januvia combined
Critcal Seriouosness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Glipizide and Januvia combined

Januvia and Glipizide Combined have 15 Most Frequently Occurring Side Effects
 
Diarrhea is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Dizzy - Dizziness is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Drowsiness - Drowsy is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Excess Urination - Polyuria is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Heartburn is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Increased Hunger - Increased Appetite is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Low Blood Sugar - Hypoglycemic Disorder is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Taste Problems - Dysgeusia is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Januvia and Glipizide combined
Weight Gain is a Frequently Occurring Side Effect of Januvia and Glipizide combined

Januvia and Glipizide Drug-Drug Interactions
 
There are no drug-drug interactions between Januvia and Glipizide.

Januvia has 6 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Januvia.

Januvia Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Januvia.

Relative Contraindications 

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Januvia.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Januvia.

Contraindication Warnings 

High Fever >101 Degrees Fahrenheit - Body Temperature More Than 101 Degrees F is a contraindication of Januvia.

Surgical Procedure - Recent Operation is a contraindication of Januvia.

Trauma - Injury is a contraindication of Januvia.

Glipizide has 14 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Glipizide.

Glipizide Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications 

Debilitation - Weakened Patient is a contraindication of Glipizide.

Hepatic Porphyria is a contraindication of Glipizide.

High Fever >101 Degrees Fahrenheit - Body Temperature More Than 101 Degrees F is a contraindication of Glipizide.

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Glipizide.

Prolonged-Severe Nausea and Vomiting - Severe Nausea and Vomiting that has Lasted a Long Time is a contraindication of Glipizide.

Contraindication Warnings 

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Glipizide.

Disease of Liver - Liver Problems is a contraindication of Glipizide.

G6PD Deficiency Anemia - G6PD Anemia is a contraindication of Glipizide.

Hemolytic Anemia is a contraindication of Glipizide.

Pituitary Insufficiency - Pituitary Hormone Deficiency is a contraindication of Glipizide.

Primary Adrenocortical Insufficiency - Addison's Disease is a contraindication of Glipizide.

Renal Disease - Kidney Disease is a contraindication of Glipizide.

Surgical Procedure - Recent Operation is a contraindication of Glipizide.

Trauma - Injury is a contraindication of Glipizide.
Januvia - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Glipizide - Symptoms of overdose may include
shakiness, rapid heartbeat, sweating, loss of consciousness.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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