Combine Januvia and Metformin

Drug Interactions and Combined Side Effects of
Januvia

and Metformin

Combine Januvia with Metformin. To make a decision about taking Januvia and Metformin, click here for a Medication Risk Map showing their individual and Combined Risks

Januvia and Metformin have 35 combined Side Effects total
12 are Life Threatening
9 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Januvia.
Click here for Drug Interactions and Side Effects of Metformin.
Click here to compare Januvia vs Metformin.

Uses of Januvia

Januvia is also known by the generic name Sitagliptin

USES:
Sitagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in people with type 2 (non-insulin-dependent) diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

Sitagliptin is an anti-diabetic drug that works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes.

This medication should not be used to treat people with type 1 diabetes (insulin-dependent diabetes).

Uses of Metformin

USES:
Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes (non-insulin-dependent diabetes). Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.

Januvia and Metformin Combined Have 12 Life Threatening (Major) Side Effects

Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Increased Blood Acidity due to High Levels of Lactic Acid - Lactic Acidosis is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Inflammation of Blood Vessels in the Skin - Cutaneous Vasculitis is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Megaloblastic Anemia is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Metformin and Januvia combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Metformin and Januvia combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Januvia and Metformin combined.

Januvia and Metformin Combined have 9 Most Frequently Occurring Side Effects

Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Frequently Occurring Side Effect of Januvia and Metformin combined

Diarrhea is a Frequently Occurring Side Effect of Januvia and Metformin combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Januvia and Metformin combined

Gas - Flatulence is a Frequently Occurring Side Effect of Januvia and Metformin combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Januvia and Metformin combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Januvia and Metformin combined

Swelling of the Abdomen - Abdominal Swelling is a Frequently Occurring Side Effect of Januvia and Metformin combined

Taste Problems - Dysgeusia is a Frequently Occurring Side Effect of Januvia and Metformin combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Januvia and Metformin combined

Click for a searchable interactive map of all Side Effects associated with Januvia and Metformin combined.

Januvia and Metformin Drug-Drug Interactions

There are no drug-drug interactions between Januvia and Metformin.

Januvia has 6 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Januvia.

Januvia Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Januvia.

Relative Contraindications

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Januvia.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Januvia.

Contraindication Warnings

High Fever >101 Degrees Fahrenheit - Body Temperature More Than 101 Degrees F is a contraindication of Januvia.

Surgical Procedure - Recent Operation is a contraindication of Januvia.

Trauma - Injury is a contraindication of Januvia.

Metformin has 26 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Metformin.

Metformin Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Decompensated Heart Failure - Suddenly Serious Symptoms of Heart Failure is a contraindication of Metformin.

Alcohol Intoxication is a contraindication of Metformin.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Metformin.

Cardiogenic Shock - Blood Circulation Failure due to Serious Heart Condition is a contraindication of Metformin.

Dehydration - Extreme Loss of Body Water is a contraindication of Metformin.

Disease of Liver - Liver Problems is a contraindication of Metformin.

Ketoacidosis is a contraindication of Metformin.

Lactic Acidosis - Increased Blood Acidity due to High Levels of Lactic Acid is a contraindication of Metformin.

Metabolic Acidosis - Excess Body Acid is a contraindication of Metformin.

Myocardial Infarction - Heart Attack is a contraindication of Metformin.

Radiography with IV Iodinated Contrast Agent - X-Ray Study with Intravenous Iodine Contrast Agent is a contraindication of Metformin.

Renal Disease - Kidney Disease is a contraindication of Metformin.

Sepsis Syndrome is a contraindication of Metformin.

Severe Hypoxemia - Serious Lack of Oxygen in the Blood is a contraindication of Metformin.

Shock is a contraindication of Metformin.

Surgical Procedure - Recent Operation is a contraindication of Metformin.

Trauma - Injury is a contraindication of Metformin.

Relative Contraindications

Adrenocortical Insufficiency - Decreased Function of the Adrenal Gland is a contraindication of Metformin.

Debilitation - Weakened Patient is a contraindication of Metformin.

Fever is a contraindication of Metformin.

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Metformin.

Infection is a contraindication of Metformin.

Pituitary Insufficiency - Pituitary Hormone Deficiency is a contraindication of Metformin.

Severe Diarrhea is a contraindication of Metformin.

Severe Vomiting is a contraindication of Metformin.

Contraindication Warnings

Vitamin B12 Deficiency - Inadequate Vitamin B12 is a contraindication of Metformin.

Januvia - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Metformin - Symptoms of overdose may include
severe drowsiness, severe nausea/vomiting/diarrhea, rapid breathing, slow/irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.