Combine Lamictal and Depakote

Drug Interactions and Combined Side Effects of
Lamictal

and Depakote

Combine Lamictal with Depakote. To make a decision about taking Lamictal and Depakote, click here for a Medication Risk Map showing their individual and Combined Risks

Lamictal and Depakote have 95 combined Side Effects total
51 are Life Threatening
25 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Lamictal.
Click here for Drug Interactions and Side Effects of Depakote.
Click here to compare Lamictal vs Depakote.

Uses of Lamictal

Lamictal is also known by the generic name Lamotrigine

USES:
Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults.

Lamotrigine is known as an anticonvulsant or antiepileptic drug. It is thought to work by restoring the balance of certain natural substances in the brain.

Uses of Depakote

Depakote is also known by the generic name Divalproex USES: This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.

Lamictal and Depakote Combined Have 51 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Anemia is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Anxious - Anxiety is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Blood Disorder - Blood Dyscrasias is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Blurred Vision is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Decrease in the Ability of Platelet Cells to Clot - Platelet Aggregation Inhibition is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Double Vision - Diplopia is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Easily Angered or Annoyed - Irritability is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Erythema Multiforme is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Fever is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Hemolytic Anemia is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - High Amount of Ammonium in the Blood - Hyperammonemia is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Increased Eosinophils in the Blood - Eosinophilia is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Involuntary Eye Movement - Nystagmus is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Low Body Temperature - Hypothermia is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Lupus-Like Syndrome is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Meningitis Not Caused by an Infection - Non-Infective Meningitis is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Mental Impairment is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Multiple Organ Failure is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Pancreatitis is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Periods of Not Breathing - Apnea is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Problem Behavior - Behavioral Disorders is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Problems with Eyesight - Visual Changes is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Repeated Seizures with Unconsciousness Between Episodes - Status Epilepticus is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Seeing Spots - Visual Disturbance of Seeing Spots is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Small Reddish-Purplish Pin-Point Sized Spots on the Skin - Petechiae is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Suicidal is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Toxic Effect on Brain or Spinal Cord Function - CNS Toxicity is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Uncoordinated - Ataxia is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Vasculitis is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Voluntary Movement Difficulty - Dyskinesia is a Life Threatening Side Effect of Depakote and Lamictal combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Depakote and Lamictal combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Lamictal and Depakote combined.

Lamictal and Depakote Combined have 25 Most Frequently Occurring Side Effects

Blurred Vision is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Chest Pain is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Diarrhea is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Disorder of the Digestive System is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Double Vision - Diplopia is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Hair Loss - Alopecia is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Infection is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Inflammation of the Nose - Rhinitis is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Irregular Periods - Irregular Menstrual Periods is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Rash - Skin Rash is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Uncoordinated - Ataxia is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Weight Gain is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Weight Loss is a Frequently Occurring Side Effect of Lamictal and Depakote combined

Click for a searchable interactive map of all Side Effects associated with Lamictal and Depakote combined.

Lamictal and Depakote Drug-Drug Interactions

When combined Lamictal and Depakote have the following 1 Drug-Drug Interaction(s):

When combined Lamictal and Depakote have the following interaction of Serious seriousness: Concurrent therapy results in increased levels of lamotrigine, requiring dosage adjustments. Valproic acid levels may also decrease over the first three weeks of therapy. Coadministration of valproic acid may increase the risk of potentially life-threatening lamotrigine-induced rashes.

Click for a searchable interactive map of all interactions between Lamictal and Depakote.

Lamictal has 11 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Lamictal.

Lamictal Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Pregnancy is a contraindication of Lamictal.

Relative Contraindications

Non-Infective Meningitis - Meningitis Not Caused by an Infection is a contraindication of Lamictal.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Lamictal.

Contraindication Warnings

Anemia is a contraindication of Lamictal.

Aplastic Anemia - Low Blood Counts due to Bone Marrow Failure is a contraindication of Lamictal.

Depression is a contraindication of Lamictal.

Disease of Liver - Liver Problems is a contraindication of Lamictal.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Lamictal.

Pancytopenia - Acquired Decrease of All Cells in the Blood is a contraindication of Lamictal.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Lamictal.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Lamictal.

Depakote has 16 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Depakote.

Depakote Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Depakote.

Carbamyl Phosphate Synthetase Deficiency - Inherited Deficiency of Carbamyl Phosphate Synthetase is a contraindication of Depakote.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Depakote.

Disease of Liver - Liver Problems is a contraindication of Depakote.

Ornithine Carbamyltransferase Deficiency is a contraindication of Depakote.

Pregnancy is a contraindication of Depakote.

Relative Contraindications

Hyperammonemia - High Amount of Ammonium in the Blood is a contraindication of Depakote.

Porphyria is a contraindication of Depakote.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Depakote.

Contraindication Warnings

Blood Dyscrasias - Blood Disorder is a contraindication of Depakote.

Depression is a contraindication of Depakote.

Hypoalbuminemia - Low Amount of Albumin Proteins in the Blood is a contraindication of Depakote.

Organic Mental Disorder - Dysfunction of the Brain is a contraindication of Depakote.

Renal Disease - Kidney Disease is a contraindication of Depakote.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Depakote.

Valproic Acid Toxicity - Poisoning by Drug Valproic Acid is a contraindication of Depakote.

Lamictal - Symptoms of overdose may include
severe drowsiness, unusual eye movements, loss of consciousness.

Depakote - Symptoms of overdose may include
excessive drowsiness, coma, irregular/slowed/skipped heart beats (heart block).

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.