Combine Oxycontin and Coumadin

Drug Interactions and Combined Side Effects of
Oxycontin

and Coumadin

Combine Oxycontin with Coumadin. To make a decision about taking Oxycontin and Coumadin, click here for a Medication Risk Map showing their individual and Combined Risks

Oxycontin and Coumadin have 96 combined Side Effects total
56 are Life Threatening
8 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Oxycontin.
Click here for Drug Interactions and Side Effects of Coumadin.
Click here to compare Oxycontin vs Coumadin.

Uses of Oxycontin

Oxycontin is also known by the generic name Oxycodone

USES:
This medication is used to help relieve moderate to severe ongoing pain (such as due to cancer). Oxycodone belongs to a class of drugs known as narcotic (opiate) analgesics. It works in the brain to change how your body feels and responds to pain.

Do not use the sustained-action form of oxycodone to relieve pain that is mild or that will go away in a few days. This medication is not for occasional ("as needed") use.

Uses of Coumadin

Coumadin is also known by the generic name Warfarin

USES:
This medication is used to treat blood clots (such as in deep vein thrombosis-DVT or pulmonary embolus-PE) and/or to prevent new clots from forming in your body. Preventing harmful blood clots helps to reduce the risk of a stroke or heart attack. Conditions that increase your risk of developing blood clots include a certain type of irregular heart rhythm (atrial fibrillation), heart valve replacement, recent heart attack, and certain surgeries (such as hip/knee replacement).

Warfarin is commonly called a "blood thinner," but the more correct term is "anticoagulant." It helps to keep blood flowing smoothly in your body by decreasing the amount of certain substances (clotting proteins) in your blood.

Oxycontin and Coumadin Combined Have 56 Life Threatening (Major) Side Effects

Critcal Seriouosness - A Spasm of the Larynx - Laryngismus is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Abnormal Increase in Muscle Tone - Hypertonia is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Adrenal Hemorrhage is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Blocked Bowels with No Movement - Ileus is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Blood Clot in Vein - Thrombophlebitis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Bloody Urine - Hematuria is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Canker Sore - Aphthous Stomatitis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Collapsed Portion of Lung - Atelectasis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Depression is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Diarrhea is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Feel Like Throwing Up - Nausea is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Foot Pain - Feet Pain is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Gangrene is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Hemorrhage is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Increased Risk of Bleeding is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Inflammation of the Liver with Stoppage of Bile Flow - Cholestatic Hepatitis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Injury - Trauma is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Kidney Disease - Renal Disease is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Lack of Blood Supply to the Brain - Cerebral Ischemia is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Lung Failure causing Loss of Breath - Respiratory Insufficiency is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Muscle Pain - Myalgia is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Obstruction of Blood Vessel caused by a Fat Globule - Cholesterol Embolism is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Pain in Arms or Legs - Limb Pain is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Pancreatitis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Periods of Not Breathing - Apnea is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Problem with Adrenal Gland - Acute Adrenocortical Insufficiency is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Problems with Circulation - Circulatory Depression is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Purplish Discoloration of the Skin that Looks Like Netting - Livedo Reticularis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Shock is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Significant Decrease in Lung Function - Respiratory Depression is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Throwing Up - Vomiting is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Tissue Death - Tissue Necrosis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Ulcer of the Throat - Throat Ulceration is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Vasculitis is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Visible Water Retention - Edema is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Widening of Blood Vessels - Vasodilation of Blood Vessels is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Coumadin and Oxycontin combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Oxycontin and Coumadin combined.

Oxycontin and Coumadin Combined have 8 Most Frequently Occurring Side Effects

Abnormally Low Blood Pressure - Hypotension is a Frequently Occurring Side Effect of Oxycontin and Coumadin combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Oxycontin and Coumadin combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Oxycontin and Coumadin combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Oxycontin and Coumadin combined

Feeling Faint - Fainting is a Frequently Occurring Side Effect of Oxycontin and Coumadin combined

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Oxycontin and Coumadin combined

Not Feeling Well - Malaise is a Frequently Occurring Side Effect of Oxycontin and Coumadin combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Oxycontin and Coumadin combined

Click for a searchable interactive map of all Side Effects associated with Oxycontin and Coumadin combined.

Oxycontin and Coumadin Drug-Drug Interactions

There are no drug-drug interactions between Oxycontin and Coumadin.

Oxycontin has 42 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Oxycontin.

Oxycontin Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Acutely Deteriorating Asthma - Asthma That Is Getting Worse is a contraindication of Oxycontin.

Alcohol Intoxication is a contraindication of Oxycontin.

Alcohol Withdrawal Delirium - Psychosis caused by Sudden Alcohol Withdrawal is a contraindication of Oxycontin.

Benign Prostatic Hypertrophy - Enlarged Prostate is a contraindication of Oxycontin.

Bradycardia - Slow Heartbeat is a contraindication of Oxycontin.

Brain Neoplasm - Brain Tumor is a contraindication of Oxycontin.

CNS Depression - Abnormal Nervous System Function Affecting Mental Alertness is a contraindication of Oxycontin.

Coma is a contraindication of Oxycontin.

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Oxycontin.

Cor Pulmonale is a contraindication of Oxycontin.

Debilitation - Weakened Patient is a contraindication of Oxycontin.

Dehydration - Extreme Loss of Body Water is a contraindication of Oxycontin.

Gastrointestinal Tract Surgery - Stomach or Intestinal Tract Operation is a contraindication of Oxycontin.

Head Injury is a contraindication of Oxycontin.

Hypercapnia - Excess Amount of Carbon Dioxide in the Blood is a contraindication of Oxycontin.

Hypotension - Abnormally Low Blood Pressure is a contraindication of Oxycontin.

Hypoxia - Decreased Oxygen In The Tissues Or Blood is a contraindication of Oxycontin.

Inflammatory Bowel Disease is a contraindication of Oxycontin.

Intracranial Hypertension - High Pressure Within the Skull is a contraindication of Oxycontin.

Intracranial Lesion - Lesion of Brain is a contraindication of Oxycontin.

Morbid Obesity is a contraindication of Oxycontin.

Primary Adrenocortical Insufficiency - Addison's Disease is a contraindication of Oxycontin.

Pulmonary Emphysema - Emphysema is a contraindication of Oxycontin.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Oxycontin.

Seizure Disorder - Seizures is a contraindication of Oxycontin.

Shock is a contraindication of Oxycontin.

Substance Abuse - Misuse or Excessive Use of Drugs is a contraindication of Oxycontin.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Oxycontin.

Toxic Psychosis - Mental Disorder Resulting from Poisonous Agents is a contraindication of Oxycontin.

Ulcerative Colitis - Ulcerated Colon is a contraindication of Oxycontin.

Untreated Hypothyroidism - Untreated Decreased Level of Thyroid Hormones is a contraindication of Oxycontin.

Urethral Stricture - Narrowing of the Tube that Empties Urine From the Bladder is a contraindication of Oxycontin.

Urinary Retention - Cannot Empty Bladder is a contraindication of Oxycontin.

Contraindication Warnings

Acute Abdominal Pain - Intense Abdominal Pain is a contraindication of Oxycontin.

Biliary Spasm - Spasm of a Bile Duct Tract is a contraindication of Oxycontin.

Constipation - Incomplete or Infrequent Bowel Movements is a contraindication of Oxycontin.

Disease of Liver - Liver Problems is a contraindication of Oxycontin.

Drug Dependence - Taking Habit Forming Drugs is a contraindication of Oxycontin.

Gallbladder Disease - Disease of the Gallbladder is a contraindication of Oxycontin.

Hypothyroidism - Underactive Thyroid is a contraindication of Oxycontin.

Mood Changes is a contraindication of Oxycontin.

Renal Disease - Kidney Disease is a contraindication of Oxycontin.

Coumadin has 60 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Coumadin.

Coumadin Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Aortic Aneurysm with Dissection - Bulge and Tear of the Aorta Blood Vessel Wall is a contraindication of Coumadin.

Bacterial Endocarditis - Bacterial Infection of Heart Valve is a contraindication of Coumadin.

Blood Coagulation Disorder - Blood Clotting Disorder is a contraindication of Coumadin.

Brain Aneurysm - Balloon-Like Swelling of an Artery of the Brain is a contraindication of Coumadin.

Cerebrovascular Hemorrhage - Hemorrhage in the Brain is a contraindication of Coumadin.

Eclampsia of Pregnancy - Seizures with Pregnancy is a contraindication of Coumadin.

Gastrointestinal Hemorrhage - Bleeding of the Stomach or Intestines is a contraindication of Coumadin.

Gastrointestinal Ulcer - Stomach or Intestinal Ulcer is a contraindication of Coumadin.

Genitourinary Tract Hemorrhage - Bleeding from the Genitourinary System is a contraindication of Coumadin.

Hemorrhage is a contraindication of Coumadin.

Internal Hemorrhage - Internal Bleeding is a contraindication of Coumadin.

Open Procedure on Central Nervous System - Operation on the Nervous System is a contraindication of Coumadin.

Pericardial Effusion - Fluid in the Covering of the Heart or Pericardium is a contraindication of Coumadin.

Pericarditis - Inflammation of the Covering of the Heart or Pericardium is a contraindication of Coumadin.

Pregnancy is a contraindication of Coumadin.

Respiratory Tract Hemorrhage - Bleeding from the Respiratory Tract is a contraindication of Coumadin.

Severe Uncontrolled Hypertension - Severe Uncontrolled High Blood Pressure is a contraindication of Coumadin.

Spinal Anesthesia - Local Anesthesia Injected into Spine is a contraindication of Coumadin.

Spinal Puncture - Spinal Tap is a contraindication of Coumadin.

Surgical Procedure on Eye Proper - Eye Surgery is a contraindication of Coumadin.

Threatened Abortion - Possibility of Having a Miscarriage is a contraindication of Coumadin.

Relative Contraindications

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Coumadin.

Cerebrovascular Disorder - Any Disorder of the Blood Vessels of the Brain is a contraindication of Coumadin.

Cholesterol Embolism - Obstruction of Blood Vessel caused by a Fat Globule is a contraindication of Coumadin.

Gangrene is a contraindication of Coumadin.

Heparin-Induced Thrombocytopenia - Decreased Platelets due to the Medication Heparin is a contraindication of Coumadin.

Increased Risk of Bleeding is a contraindication of Coumadin.

Indwelling Vascular Catheter - Patient with Catheter in the Vascular System is a contraindication of Coumadin.

Moderate Hypertension - Moderate High Blood Pressure is a contraindication of Coumadin.

Polycythemia Vera - Increased Red Blood Cells is a contraindication of Coumadin.

Protein C Deficiency Disease is a contraindication of Coumadin.

Psychotic Disorder - Mental Disorder with Loss of Normal Personality & Reality is a contraindication of Coumadin.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Coumadin.

Secondary Uterine Inertia is a contraindication of Coumadin.

Severe Diabetes Mellitus - Severe Form of Diabetes is a contraindication of Coumadin.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Coumadin.

Severe and Chronic Diarrhea - Serious Loose Stools Lasting a Long Time is a contraindication of Coumadin.

Surgical Procedure - Recent Operation is a contraindication of Coumadin.

Tissue Necrosis - Tissue Death is a contraindication of Coumadin.

Trauma - Injury is a contraindication of Coumadin.

Tropical Sprue is a contraindication of Coumadin.

Vasculitis is a contraindication of Coumadin.

Vitamin K Deficiency - Inadequate Vitamin K is a contraindication of Coumadin.

Contraindication Warnings

Anemia is a contraindication of Coumadin.

Biliary Obstruction - Blockage of a Bile Duct is a contraindication of Coumadin.

Bleeding Risk Associated with Vitamin-K-Epoxide Reductase (Warfarin-Sensitive) Gene is a contraindication of Coumadin.

Connective Tissue Disease - Disorder of the Connective Tissue is a contraindication of Coumadin.

Disease of Liver - Liver Problems is a contraindication of Coumadin.

Edema - Visible Water Retention is a contraindication of Coumadin.

Fever is a contraindication of Coumadin.

Hyperlipidemia - High Amount of Fats in the Blood is a contraindication of Coumadin.

Hyperthyroidism - Overactive Thyroid Gland is a contraindication of Coumadin.

Hypothyroidism - Underactive Thyroid is a contraindication of Coumadin.

Malignancy - Malignant Tumor or Cancer is a contraindication of Coumadin.

Nephrotic Syndrome is a contraindication of Coumadin.

Nutritional Disorder - Poor Nutrition is a contraindication of Coumadin.

Poor Metabolizer due to Cytochrome p450 CYP2C9 Variant is a contraindication of Coumadin.

Severe Diarrhea is a contraindication of Coumadin.

Steatorrhea - Bowel Movements Containing Much Fat is a contraindication of Coumadin.

Viral Hepatitis - Viral Infection of the Liver is a contraindication of Coumadin.

Oxycontin - Symptoms of overdose may include
slow breathing, slow heartbeat, loss of consciousness.

Coumadin - Symptoms of overdose may include
bloody/black/tarry stools, pink/dark urine, unusual/prolonged bleeding.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.