Combine Skelaxin and Naproxen

Drug Interactions and Combined Side Effects of
Skelaxin

and Naproxen

Combine Skelaxin with Naproxen. To make a decision about taking Skelaxin and Naproxen, click here for a Medication Risk Map showing their individual and Combined Risks

Skelaxin and Naproxen have 134 combined Side Effects total
102 are Life Threatening
15 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Skelaxin.
Click here for Drug Interactions and Side Effects of Naproxen.
Click here to compare Skelaxin vs Naproxen.

Uses of Skelaxin

Skelaxin is also known by the generic name Metaxalone USES: This medication relaxes muscles. It is used along with rest and physical therapy to decrease muscle pain and spasms associated with strains, sprains or other muscle injuries.

Uses of Naproxen

USES:
Naproxen is used to relieve mild to moderate pain from various conditions. It reduces pain, swelling, and joint stiffness caused by arthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).

Enteric-coated tablets of naproxen are absorbed more slowly into your bloodstream than other forms of naproxen. Therefore, they should not be taken to relieve sudden pain (e.g., from gout attacks, menstrual pain, tendonitis, bursitis). Ask your doctor or pharmacist about other medications that can quickly relieve sudden pain from these conditions.

Skelaxin and Naproxen Combined Have 102 Life Threatening (Major) Side Effects

Critcal Seriouosness - A Rupture in the Wall of the Stomach or Intestine - Gastrointestinal Perforation is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Acquired Decrease of All Cells in the Blood - Pancytopenia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Anemia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Anxious - Anxiety is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Bacterial Infection of Blood or Tissues affecting the Whole Body - Bacterial Septicemia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Bleeding Not Related to Menstrual Period - Metrorrhagia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Blood Clot - Thrombotic Disorder is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Bloody Urine - Hematuria is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Blurred Vision is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Bruise - Bruising is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Canker Sore - Aphthous Stomatitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Chest Tightness is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Chronic Heart Failure is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Coma is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Corneal Scar - Corneal Opacity is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Cramps is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Depression is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Disease of the Heart and Blood Vessels - Disease of Cardiovascular System is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Double Vision - Diplopia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Elevation of Proteins in the Urine - Proteinuria is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Erythema Multiforme is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Excess Urination - Polyuria is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Excessive Thirst - Polydipsia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Fever is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Fit - Tonic Clonic Seizure is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Fluid in the Lungs - Pulmonary Edema is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Glomerulonephritis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Hearing Problem - Hearing Disorder is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Heart Attack - Myocardial Infarction is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Hemolytic Anemia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Hemorrhage of Blood Under the Skin - Ecchymosis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - High Amount of Potassium in the Blood - Hyperkalemia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - High Blood Sugar - Hyperglycemia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Increased Eosinophils in the Blood - Eosinophilia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Infiltration of White Blood Cells into the Lungs - Loeffler Syndrome is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Inflammation of the Bladder - Cystitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Inflammation of the Large Intestine - Colitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Interstitial Nephritis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Kidney Damage - Nephrotoxicity is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Kidney Disease - Renal Disease is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Kidney Failure - Renal Failure is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Large Purple or Brown Skin Blotches - Purpura is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Low Blood Counts due to Bone Marrow Failure - Aplastic Anemia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Lupus-Like Syndrome is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Meningitis Not Caused by an Infection - Non-Infective Meningitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Mental Impairment is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Mood Changes is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Muscle Pain - Myalgia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Nephrotic Syndrome is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Pneumonia with High Amount of Eosinophil White Blood Cells - Eosinophilic Pneumonia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Pneumonia is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Problems with Eyesight - Visual Changes is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Red Blood in Bowel Movement - Bloody Stools is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Renal Papillary Necrosis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Renal Tubular Necrosis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Ringing in the Ears - Tinnitus is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Significant Decrease in Lung Function - Respiratory Depression is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Skin Rash with Sloughing - Exfoliative Dermatitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Stomach or Intestinal Ulcer - Gastrointestinal Ulcer is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Stroke - Cerebrovascular Accident is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Sudden Blindness and Pain Upon Moving the Eye - Optic Neuritis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Throwing Up Blood - Bloody Vomit is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Ulcer from Stomach Acid - Peptic Ulcer is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Ulcers of Esophagus - Esophageal Ulcer is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Vasculitis is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Visible Water Retention - Edema is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Water Retention - Body Fluid Retention is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Wheezing is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Naproxen and Skelaxin combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Skelaxin and Naproxen combined.

Skelaxin and Naproxen Combined have 15 Most Frequently Occurring Side Effects

Dizzy - Dizziness is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Heartburn is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Hives - Urticaria is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Irritation of the Stomach or Intestines - Gastrointestinal Irritation is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Nervous - Nervousness is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Rash - Skin Rash is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Visible Water Retention - Edema is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Water Retention - Body Fluid Retention is a Frequently Occurring Side Effect of Skelaxin and Naproxen combined

Click for a searchable interactive map of all Side Effects associated with Skelaxin and Naproxen combined.

Skelaxin and Naproxen Drug-Drug Interactions

There are no drug-drug interactions between Skelaxin and Naproxen.

Skelaxin has 5 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Skelaxin.

Skelaxin Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Hepatic Failure - Acute Liver Failure is a contraindication of Skelaxin.

Hemolytic Anemia is a contraindication of Skelaxin.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Skelaxin.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Skelaxin.

Contraindication Warnings

Chronic Hepatic Disease - Recurring Liver Problems is a contraindication of Skelaxin.

Naproxen has 24 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Naproxen.

Naproxen Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Post-operative from CABG Surgery - Time Immediately after Coronary Bypass Surgery is a contraindication of Naproxen.

Pregnancy is a contraindication of Naproxen.

Relative Contraindications

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Naproxen.

Anemia is a contraindication of Naproxen.

Body Fluid Retention - Water Retention is a contraindication of Naproxen.

Cerebrovascular Accident - Stroke is a contraindication of Naproxen.

Chronic Heart Failure is a contraindication of Naproxen.

Disease of Cardiovascular System - Disease of the Heart and Blood Vessels is a contraindication of Naproxen.

Disease of Liver - Liver Problems is a contraindication of Naproxen.

Edema - Visible Water Retention is a contraindication of Naproxen.

Esophageal Dysmotility - Problems with Food Passing Through the Esophagus is a contraindication of Naproxen.

Gastrointestinal Hemorrhage - Bleeding of the Stomach or Intestines is a contraindication of Naproxen.

Gastrointestinal Perforation - A Rupture in the Wall of the Stomach or Intestine is a contraindication of Naproxen.

Gastrointestinal Ulcer - Stomach or Intestinal Ulcer is a contraindication of Naproxen.

Hypertension - High Blood Pressure is a contraindication of Naproxen.

Hypovolemia - Decreased Blood Volume is a contraindication of Naproxen.

Increased Cardiovascular Event Risk is a contraindication of Naproxen.

Myocardial Infarction - Heart Attack is a contraindication of Naproxen.

Renal Disease - Kidney Disease is a contraindication of Naproxen.

Thromboembolic Disorder - Obstruction of a Blood Vessel by a Blood Clot is a contraindication of Naproxen.

Tobacco Smoker - Tobacco Smoking is a contraindication of Naproxen.

Contraindication Warnings

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Naproxen.

Anemia is a contraindication of Naproxen.

Blood Coagulation Disorder - Blood Clotting Disorder is a contraindication of Naproxen.

Skelaxin - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe drowsiness or unconsciousness.

Naproxen - Symptoms of overdose may include
severe stomach pain, vomit that looks like coffee grounds, extreme drowsiness, slow or shallow breathing, seizures.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.