Combine Suboxone and Fentanyl

Drug Interactions and Combined Side Effects of
Suboxone

and Fentanyl

Combine Suboxone with Fentanyl. To make a decision about taking Suboxone and Fentanyl, click here for a Medication Risk Map showing their individual and Combined Risks

Suboxone and Fentanyl have 74 combined Side Effects total
41 are Life Threatening
31 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Suboxone.
Click here for Drug Interactions and Side Effects of Fentanyl.
Click here to compare Suboxone vs Fentanyl.

Uses of Suboxone

Suboxone is also known by the generic name Buprenorphine-Naloxone

USES:
This medication contains 2 medicines:
buprenorphine and naloxone. It is used to treat narcotic (opioid) dependence/addiction. Buprenorphine belongs to a class of drugs called mixed narcotic agonist-antagonists. Buprenorphine helps prevent withdrawal symptoms caused by stopping other opiate-type narcotics.

Naloxone is a narcotic antagonist that blocks the effect of narcotics and can cause severe narcotic withdrawal when injected. It has little effect when taken by mouth or dissolved under the tongue. It is combined with buprenorphine to prevent abuse and misuse (injection) of this medication. This combination medication is used as part of a complete treatment program for drug abuse (such as compliance monitoring, counseling, behavioral contract, lifestyle changes).

Uses of Fentanyl

USES: This medication is used to help relieve moderate to severe ongoing pain (such as due to cancer). Fentanyl belongs to a class of drugs known as narcotic (opiate) analgesics. It works in the brain to change how your body feels and responds to pain.

Suboxone and Fentanyl Combined Have 41 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Abnormal Nervous System Function Affecting Mental Alertness - CNS Depression is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Abscess is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Asthma - Bronchial Asthma is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Backache - Back Pain is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Bladder Pain is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Breathing Changes - Respiration Changes is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Cannot Empty Bladder - Urinary Retention is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Chest Pain is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Chest Tightness is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Coughing Up Blood - Hemoptysis is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Depression is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Fever is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Infection is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Kidney Problems Causing a Decreased Amount of Urine to be Passed - Oliguria is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Lazy Eye - Amblyopia is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Needing to Urinate Immediately - Urinary Urgency is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Pain is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Paranoia - Paranoid Disorder is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Periods of Not Breathing - Apnea is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Significant Decrease in Lung Function - Respiratory Depression is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Signs and Symptoms at Injection Site - Injection Site Sequelae is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Skin Rash with Sloughing - Exfoliative Dermatitis is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Slurred Speech is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Small Skin Blister - Blistering Skin is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Swelling of the Abdomen - Abdominal Swelling is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Toxic Effect on Brain or Spinal Cord Function - CNS Toxicity is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Unsteady Walking - Unsteady Gait is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Voluntary Movement Difficulty - Dyskinesia is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Wheezing is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Fentanyl and Suboxone combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Suboxone and Fentanyl combined.

Suboxone and Fentanyl Combined have 31 Most Frequently Occurring Side Effects

Abnormal Nervous System Function Affecting Mental Alertness - CNS Depression is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Anxious - Anxiety is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Backache - Back Pain is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Cannot Empty Bladder - Urinary Retention is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Conditions of Excess Stomach Acid Secretion - Gastric Hypersecretory Conditions is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Confused - Impaired Cognition is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Depression is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Diarrhea is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

False Sense of Well-Being is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Fever is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Flu-Like Symptoms is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Hallucination - Hallucinations is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Infection is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Itching - Pruritus of Skin is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Nervous - Nervousness is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Pain is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Periods of Not Breathing - Apnea is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Trouble Breathing - Dyspnea is a Frequently Occurring Side Effect of Suboxone and Fentanyl combined

Click for a searchable interactive map of all Side Effects associated with Suboxone and Fentanyl combined.

Suboxone and Fentanyl Drug-Drug Interactions

When combined Suboxone and Fentanyl have the following 1 Drug-Drug Interaction(s):

When combined Suboxone and Fentanyl have the following interaction of Moderate seriousness: Concurrent use of buprenorphine, butorphanol, or nalbuphine with other opioids in opioid dependent patients may result in withdrawal symptoms. Concurrent use in other patients may result in additive or decreased analgesia, decreased opioid side effects, and/or renarcotization.

Click for a searchable interactive map of all interactions between Suboxone and Fentanyl.

Suboxone has 31 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Suboxone.

Suboxone Sublingual Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Pain in Opioid Naive Patients is a contraindication of Suboxone.

Paralytic Ileus - Paralysis of the Intestines is a contraindication of Suboxone.

Relative Contraindications

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Suboxone.

Alcohol Intoxication is a contraindication of Suboxone.

CNS Depression - Abnormal Nervous System Function Affecting Mental Alertness is a contraindication of Suboxone.

Chronic Disease of Respiratory System - Chronic Lung or Breathing Passage Problem is a contraindication of Suboxone.

Chronic Hepatitis C is a contraindication of Suboxone.

Chronic Obstructive Pulmonary Disease - Chronic Obstructive Lung Disease is a contraindication of Suboxone.

Chronic Type B Viral Hepatitis - Chronic Hepatitis B is a contraindication of Suboxone.

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Suboxone.

Cor Pulmonale is a contraindication of Suboxone.

Head Injury is a contraindication of Suboxone.

Hypercapnia - Excess Amount of Carbon Dioxide in the Blood is a contraindication of Suboxone.

Hypoxia - Decreased Oxygen In The Tissues Or Blood is a contraindication of Suboxone.

Intracranial Hypertension - High Pressure Within the Skull is a contraindication of Suboxone.

Intracranial Lesion - Lesion of Brain is a contraindication of Suboxone.

Kyphoscoliosis with Respiratory Compromise - Curvature of the Spine with Respiratory Compromise is a contraindication of Suboxone.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Suboxone.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Suboxone.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Suboxone.

Respiratory Insufficiency - Lung Failure causing Loss of Breath is a contraindication of Suboxone.

Torsades de Pointes - Very Rapid Heartbeat - Torsades de Pointes is a contraindication of Suboxone.

Toxic Psychosis - Mental Disorder Resulting from Poisonous Agents is a contraindication of Suboxone.

Untreated Hypothyroidism - Untreated Decreased Level of Thyroid Hormones is a contraindication of Suboxone.

Contraindication Warnings

Adrenocortical Insufficiency - Decreased Function of the Adrenal Gland is a contraindication of Suboxone.

Alcohol Withdrawal Delirium - Psychosis caused by Sudden Alcohol Withdrawal is a contraindication of Suboxone.

Benign Prostatic Hypertrophy - Enlarged Prostate is a contraindication of Suboxone.

Biliary Tract Disorder - Biliary and Gallbladder Problem is a contraindication of Suboxone.

Debilitation - Weakened Patient is a contraindication of Suboxone.

Disease of Liver - Liver Problems is a contraindication of Suboxone.

Urethral Stricture - Narrowing of the Tube that Empties Urine From the Bladder is a contraindication of Suboxone.

Fentanyl has 24 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Fentanyl.

Fentanyl Transdermal Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Asthma Attack - Asthma Attack is a contraindication of Fentanyl.

Acute Postoperative Pain in Patients without Opiate Tolerance - Acute Pain Following Operation without Opiate Tolerance is a contraindication of Fentanyl.

Headache Pain especially in Patients who are not Opiate Tolerant is a contraindication of Fentanyl.

Pain in Opioid Naive Patients is a contraindication of Fentanyl.

Paralytic Ileus - Paralysis of the Intestines is a contraindication of Fentanyl.

Refractory Extrinsic Asthma - Allergic Asthma that is Resistant to Treatment is a contraindication of Fentanyl.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Fentanyl.

Relative Contraindications

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Fentanyl.

Chronic Disease of Respiratory System - Chronic Lung or Breathing Passage Problem is a contraindication of Fentanyl.

Chronic Obstructive Pulmonary Disease - Chronic Obstructive Lung Disease is a contraindication of Fentanyl.

Cor Pulmonale is a contraindication of Fentanyl.

Head Injury is a contraindication of Fentanyl.

Inflammatory Bowel Disease is a contraindication of Fentanyl.

Intracranial Hypertension - High Pressure Within the Skull is a contraindication of Fentanyl.

Intracranial Lesion - Lesion of Brain is a contraindication of Fentanyl.

Substance Abuse - Misuse or Excessive Use of Drugs is a contraindication of Fentanyl.

Urinary Retention - Cannot Empty Bladder is a contraindication of Fentanyl.

Contraindication Warnings

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Fentanyl.

Benign Prostatic Hypertrophy - Enlarged Prostate is a contraindication of Fentanyl.

Biliary Tract Disorder - Biliary and Gallbladder Problem is a contraindication of Fentanyl.

Bradycardia - Slow Heartbeat is a contraindication of Fentanyl.

Disease of Liver - Liver Problems is a contraindication of Fentanyl.

Renal Disease - Kidney Disease is a contraindication of Fentanyl.

Urethral Stricture - Narrowing of the Tube that Empties Urine From the Bladder is a contraindication of Fentanyl.

Suboxone - Symptoms of overdose may include
slow breathing, slow heartbeat, loss of consciousness.

Fentanyl - Symptoms of overdose may include
slow/shallow breathing, slow heartbeat, loss of consciousness.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.