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Uses of Xeloda
 
Xeloda is also known by the generic name Capecitabine


USES:
Capecitabine is used alone or with other treatments/medications to treat certain types of cancer (e.g., of the breast, colon, rectum). It works by slowing or stopping cancer cell growth and by decreasing tumor size.


Uses of Lapatinib
 
USES:
Lapatinib is used together with another medication (capecitabine) to treat a certain type of breast cancer (HER2-positive) that has not responded to the standard treatment. It works by slowing or stopping the growth of cancer cells.


Xeloda and Lapatinib Combined Have 54 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Anemia is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Angina is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Backache - Back Pain is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Blocked Bowels with No Movement - Ileus is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Blood Clot Formation in Veins - Venous Thrombosis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Blood Clot in Lung - Pulmonary Thromboembolism is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Blood Clot in Vein - Thrombophlebitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Blood coming from Anus - Rectal Bleeding is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Burning Stomach - Gastritis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Chest Pain is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Depression is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Disease of the Muscle of the Heart with Enlargement - Cardiomyopathy is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Excess Liver Fibrous Tissue - Hepatic Fibrosis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Extreme Breathing Difficulty - Severe Dyspnea is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Extreme Loss of Body Water - Dehydration is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Failure of the Left Ventricle of the Heart - Left Ventricular Failure is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Fever is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - High Amount of Bilirubin in the Blood - Hyperbilirubinemia is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Infection is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Inflamed Colon and Small Intestine with Some Tissue Death - Necrotizing Enterocolitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Inflammation of Duodenum or Top Portion of Small Intestine - Duodenitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Inflammation of a Vein - Phlebitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Inflammation of the Esophagus - Esophagitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Inflammation of the Large Intestine - Colitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Inflammation of the Liver with Stoppage of Bile Flow - Cholestatic Hepatitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Interstitial Pneumonitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Liver Problems - Disease of Liver is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Low Platelet Count and Bleeding from Immune Response - Idiopathic Thrombocytopenic Purpura is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Lung Tissue Problems - Interstitial Lung Disease is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Painful, Red or Swollen Mouth - Stomatitis is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Severe Diarrhea is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Severe Nausea is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Sluggishness - Lethargy is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Stomach or Intestine Blockage - Gastrointestinal Obstruction is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Throwing Up - Vomiting is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Throwing Up Blood - Bloody Vomit is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Tingling, Pain, Redness and Edema of Hands and Feet - Palmar-Plantar Erythrodysesthesia is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Uncoordinated - Ataxia is a Life Threatening Side Effect of Lapatinib and Xeloda combined
Critcal Seriouosness - Visible Water Retention - Edema is a Life Threatening Side Effect of Lapatinib and Xeloda combined

Xeloda and Lapatinib Combined have 19 Most Frequently Occurring Side Effects
 
Anemia is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Decreased Blood Platelets - Thrombocytopenic Disorder is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Diarrhea is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Dry Skin is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
High Amount of Bilirubin in the Blood - Hyperbilirubinemia is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Low Energy - Fatigue is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Painful, Red or Swollen Mouth - Stomatitis is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Rash - Skin Rash is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Severe Diarrhea is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined
Tingling, Pain, Redness and Edema of Hands and Feet - Palmar-Plantar Erythrodysesthesia is a Frequently Occurring Side Effect of Xeloda and Lapatinib combined

Xeloda and Lapatinib Drug-Drug Interactions
 
There are no drug-drug interactions between Xeloda and Lapatinib.

Xeloda has 17 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Xeloda.

Xeloda Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Dihydropyrimidine Dehydrogenase Deficiency is a contraindication of Xeloda.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Xeloda.

Pregnancy is a contraindication of Xeloda.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Xeloda.

Relative Contraindications 

Anemia is a contraindication of Xeloda.

Coronary Artery Disease - Disease of the Arteries of the Heart is a contraindication of Xeloda.

Hyperbilirubinemia - High Amount of Bilirubin in the Blood is a contraindication of Xeloda.

Infection is a contraindication of Xeloda.

Necrotizing Enterocolitis - Inflamed Colon and Small Intestine with Some Tissue Death is a contraindication of Xeloda.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Xeloda.

Severe Diarrhea is a contraindication of Xeloda.

Stomatitis - Painful, Red or Swollen Mouth is a contraindication of Xeloda.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Xeloda.

Contraindication Warnings 

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Xeloda.

Disease of Liver - Liver Problems is a contraindication of Xeloda.

Palmar-Plantar Erythrodysesthesia - Tingling, Pain, Redness and Edema of Hands and Feet is a contraindication of Xeloda.

Renal Disease with Mild to Moderate Renal Function Impairment - Mild to Moderate Kidney Impairment is a contraindication of Xeloda.

Lapatinib has 13 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Lapatinib.

Lapatinib Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Interstitial Pneumonitis is a contraindication of Lapatinib.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Lapatinib.

Left Ventricular Failure - Failure of the Left Ventricle of the Heart is a contraindication of Lapatinib.

Pregnancy is a contraindication of Lapatinib.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Lapatinib.

Relative Contraindications 

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Lapatinib.

Drug-Induced Hepatitis - Hepatitis caused by Drugs is a contraindication of Lapatinib.

Hypokalemia - Low Amount of Potassium in the Blood is a contraindication of Lapatinib.

Hypomagnesemia - Low Amount of Magnesium in the Blood is a contraindication of Lapatinib.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Lapatinib.

Severe Diarrhea is a contraindication of Lapatinib.

Torsades de Pointes - Very Rapid Heartbeat - Torsades de Pointes is a contraindication of Lapatinib.

Contraindication Warnings 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Lapatinib.
Xeloda - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Lapatinib - Symptoms of overdose may include
severe diarrhea/vomiting.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

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