Combine Yaz 28 and Spironolactone

Drug Interactions and Combined Side Effects of
Yaz 28

and Spironolactone

Combine Yaz 28 with Spironolactone. To make a decision about taking Yaz 28 and Spironolactone, click here for a Medication Risk Map showing their individual and Combined Risks

Yaz 28 and Spironolactone have 74 combined Side Effects total
36 are Life Threatening
17 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Yaz 28.
Click here for Drug Interactions and Side Effects of Spironolactone.
Click here to compare Yaz 28 vs Spironolactone.

Uses of Yaz 28

Yaz 28 is also known by the generic name Drospirenone-Ethinyl Estradiol

USES:
This medication is a combination of 2 hormones:
an estrogen (ethinyl estradiol) and a progestin (drospirenone). This product is used to prevent pregnancy. It works mainly by preventing the release of an egg (ovulation) during your menstrual cycle. It also makes vaginal fluid thicker to help prevent sperm from reaching an egg (fertilization) and changes the lining of the uterus (womb) to prevent attachment of a fertilized egg. If a fertilized egg does not attach to the uterus, it passes out of the body.

This medication also may be used to treat premenstrual dysphoric disorder (PMDD) or moderate acne if you have chosen to use birth control pills as your method of pregnancy prevention.

Besides preventing pregnancy, birth control pills may make your periods more regular, decrease blood loss and painful periods, and decrease your risk of ovarian cysts.

Using this medication does not protect you or your partner against sexually transmitted diseases (such as HIV, gonorrhea, chlamydia).

Uses of Spironolactone

USES:
Spironolactone is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (e.g., congestive heart failure) by removing excess fluid and improving symptoms such as breathing problems.

This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone).

Spironolactone is known as a "water pill" (potassium-sparing diuretic).

Yaz 28 and Spironolactone Combined Have 36 Life Threatening (Major) Side Effects

Critcal Seriouosness - Absence of Menstrual Periods - Amenorrhea is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Allergic Reaction causing Inflammation of Blood Vessels - Hypersensitivity Angiitis is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Benign Tumor of Liver Cells - Benign Hepatic Cell Adenoma is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Bleeding Not Related to Menstrual Period - Metrorrhagia is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Blood Clot - Thrombotic Disorder is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Blood Clot in Lung - Pulmonary Thromboembolism is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Blood Clot in Vein - Thrombophlebitis is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Breast Tumor - Breast Neoplasm is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Depression is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Discolored Spots and Small Elevations of the Skin - Maculopapular Rash is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Disease of the Gallbladder - Gallbladder Disease is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Head Pain - Headache Disorder is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Heart Attack - Myocardial Infarction is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Hemorrhage in the Brain - Cerebrovascular Hemorrhage is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - High Amount of Fats in the Blood - Hyperlipidemia is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - High Amount of Potassium in the Blood - Hyperkalemia is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Inflammation of the Liver with Stoppage of Bile Flow - Cholestatic Hepatitis is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Inflammation or Infection of Vagina - Vaginitis is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Irregular Periods - Irregular Menstrual Periods is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Kidney Disease - Renal Disease is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Liver Cancer - Malignant Neoplasm of Liver is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Lump in the Breast - Lumps in Breasts is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Migraine Headache - Migraine is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Obstruction of a Blood Vessel by a Blood Clot - Thromboembolic Disorder is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Spironolactone and Yaz 28 combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Yaz 28 and Spironolactone combined.

Yaz 28 and Spironolactone Combined have 17 Most Frequently Occurring Side Effects

Absence of Menstrual Periods - Amenorrhea is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Acne - Acne Vulgaris is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Bleeding Not Related to Menstrual Period - Metrorrhagia is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Breast Fullness due to Milk Production - Breast Engorgement is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Breast Tenderness - Mastalgia is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Change in Curvature of the Eye - Change in Corneal Curvature is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Female Problems Causing Trouble in Getting Pregnant - Female Infertility is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

High Amount of Potassium in the Blood - Hyperkalemia is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Irregular Periods - Irregular Menstrual Periods is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Irritation of the Stomach or Intestines - Gastrointestinal Irritation is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Protrusion of the Cornea of the Eye - Keratoconus is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Swelling of the Abdomen - Abdominal Swelling is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Visible Water Retention - Edema is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Water Retention - Body Fluid Retention is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Frequently Occurring Side Effect of Yaz 28 and Spironolactone combined

Click for a searchable interactive map of all Side Effects associated with Yaz 28 and Spironolactone combined.

Yaz 28 and Spironolactone Drug-Drug Interactions

When combined Yaz 28 and Spironolactone have the following 1 Drug-Drug Interaction(s): When combined Yaz 28 and Spironolactone have the following interaction of Moderate seriousness: Concurrent use of drospirenone and potassium sparing diuretics may result in hyperkalemia. Click for a searchable interactive map of all interactions between Yaz 28 and Spironolactone.

Yaz 28 has 63 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Yaz 28.

Yaz 28 Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Adrenocortical Insufficiency - Decreased Function of the Adrenal Gland is a contraindication of Yaz 28.

Bed-Ridden - Bedridden Patient or One Unable to Move Around Freely is a contraindication of Yaz 28.

Breast Carcinoma - Breast Cancer is a contraindication of Yaz 28.

Cerebrovascular Accident - Stroke is a contraindication of Yaz 28.

Coronary Artery Disease - Disease of the Arteries of the Heart is a contraindication of Yaz 28.

Deep Venous Thrombosis - Blood Clot in a Deep Vein is a contraindication of Yaz 28.

Diplopia - Double Vision is a contraindication of Yaz 28.

Disease of Liver - Liver Problems is a contraindication of Yaz 28.

Estrogen-Dependent Neoplasm - Tumor that is Dependent on Estrogen for Growth is a contraindication of Yaz 28.

Hypercoagulability States - Abnormal Increase in Ability of Blood to Clot is a contraindication of Yaz 28.

Hyperkalemia - High Amount of Potassium in the Blood is a contraindication of Yaz 28.

Metrorrhagia - Bleeding Not Related to Menstrual Period is a contraindication of Yaz 28.

Myocardial Infarction - Heart Attack is a contraindication of Yaz 28.

Pregnancy is a contraindication of Yaz 28.

Pulmonary Thromboembolism - Blood Clot in Lung is a contraindication of Yaz 28.

Retinal Thrombosis - A Blood Clot within the Blood Vessels of the Eye is a contraindication of Yaz 28.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Yaz 28.

Severe Uncontrolled Hypertension - Severe Uncontrolled High Blood Pressure is a contraindication of Yaz 28.

Thromboembolic Disorder - Obstruction of a Blood Vessel by a Blood Clot is a contraindication of Yaz 28.

Relative Contraindications

Coronary Artery Disease - Disease of the Arteries of the Heart is a contraindication of Yaz 28.

Dementia - Disorder of Mental Processes due to a Brain Disease is a contraindication of Yaz 28.

Diabetes Mellitus - Diabetes is a contraindication of Yaz 28.

Endometrial Carcinoma - Cancer in the Lining of the Uterus is a contraindication of Yaz 28.

Familial History of Breast Carcinoma - Family History of Breast Cancer is a contraindication of Yaz 28.

Gallbladder Disease - Disease of the Gallbladder is a contraindication of Yaz 28.

Hypercalcemia associated with Metastatic Breast Carcinoma - High Amount of Blood Calcium from Spread of Breast Cancer is a contraindication of Yaz 28.

Hypercholesterolemia - High Cholesterol is a contraindication of Yaz 28.

Hyperlipidemia - High Amount of Fats in the Blood is a contraindication of Yaz 28.

Hyperlipoproteinemia is a contraindication of Yaz 28.

Hypertension - High Blood Pressure is a contraindication of Yaz 28.

Increased Cardiovascular Event Risk is a contraindication of Yaz 28.

Migraine - Migraine Headache is a contraindication of Yaz 28.

Obesity - Overweight is a contraindication of Yaz 28.

Ovarian Carcinoma - Cancer of the Ovary is a contraindication of Yaz 28.

Papilledema - Optic Disk Edema is a contraindication of Yaz 28.

Porphyria is a contraindication of Yaz 28.

Retinal Hemorrhage is a contraindication of Yaz 28.

Retinal Thrombosis - A Blood Clot within the Blood Vessels of the Eye is a contraindication of Yaz 28.

Systemic Lupus Erythematosus is a contraindication of Yaz 28.

Thrombophlebitis - Blood Clot in Vein is a contraindication of Yaz 28.

Tobacco Smoker - Tobacco Smoking is a contraindication of Yaz 28.

Vision Loss - Poor Vision is a contraindication of Yaz 28.

Contraindication Warnings

Body Fluid Retention - Water Retention is a contraindication of Yaz 28.

Bronchial Asthma - Asthma is a contraindication of Yaz 28.

Chloasma - Yellow-Brown Patches on Skin is a contraindication of Yaz 28.

Chorea - Irregular Involuntary Spasms of Limbs or Facial Muscles is a contraindication of Yaz 28.

Chronic Heart Failure is a contraindication of Yaz 28.

Depression is a contraindication of Yaz 28.

Diabetes Mellitus - Diabetes is a contraindication of Yaz 28.

Endometriosis is a contraindication of Yaz 28.

Epilepsy - Epileptic Seizure is a contraindication of Yaz 28.

Hepatic Porphyria is a contraindication of Yaz 28.

Hypertriglyceridemia - High Amount of Triglyceride in the Blood is a contraindication of Yaz 28.

Hypocalcemia - Low Amount of Calcium in the Blood is a contraindication of Yaz 28.

Hypothyroidism - Underactive Thyroid is a contraindication of Yaz 28.

Lumps in Breasts - Lump in the Breast is a contraindication of Yaz 28.

Mammography Abnormal is a contraindication of Yaz 28.

Migraine - Migraine Headache is a contraindication of Yaz 28.

Ovarian Carcinoma - Cancer of the Ovary is a contraindication of Yaz 28.

Renal Disease - Kidney Disease is a contraindication of Yaz 28.

Seizure Disorder - Seizures is a contraindication of Yaz 28.

Systemic Lupus Erythematosus is a contraindication of Yaz 28.

Uterine Fibroids is a contraindication of Yaz 28.

Spironolactone has 9 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Spironolactone.

Spironolactone Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Acute Renal Disease - Acute Kidney Disease is a contraindication of Spironolactone.

Anuria - Absence of Urine Formation is a contraindication of Spironolactone.

Hyperkalemia - High Amount of Potassium in the Blood is a contraindication of Spironolactone.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Spironolactone.

Relative Contraindications

Dehydration - Extreme Loss of Body Water is a contraindication of Spironolactone.

Hyperchloremic Acidosis - Excess Body Acid and Chloride is a contraindication of Spironolactone.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Spironolactone.

Hypovolemia - Decreased Blood Volume is a contraindication of Spironolactone.

Contraindication Warnings

Renal Disease - Kidney Disease is a contraindication of Spironolactone.

Yaz 28 - Symptoms of overdose may include
severe nausea and vomiting, sudden/unusual vaginal bleeding.

Spironolactone - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.