Combine Zofran and Benadryl

Drug Interactions and Combined Side Effects of
Zofran

and Benadryl

Combine Zofran with Benadryl. To make a decision about taking Zofran and Benadryl, click here for a Medication Risk Map showing their individual and Combined Risks

Zofran and Benadryl have 57 combined Side Effects total
21 are Life Threatening
7 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Zofran.
Click here for Drug Interactions and Side Effects of Benadryl.
Click here to compare Zofran vs Benadryl.

Uses of Zofran

Zofran is also known by the generic name Ondansetron Hcl USES: This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.

Uses of Benadryl

Benadryl is also known by the generic name Diphenhydramine Hcl

USES:
Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose and sneezing. It is also used to prevent and treat nausea, vomiting and dizziness caused by motion sickness. Diphenhydramine can also be used to help you relax and fall asleep.

This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its drying effects on such symptoms as watery eyes and runny nose are caused by blocking another natural substance made by your body (acetylcholine).

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

Zofran and Benadryl Combined Have 21 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Blood Disorder - Blood Dyscrasias is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Blurred Vision is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Decreased Oxygen In The Tissues Or Blood - Hypoxia is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Extra Heartbeat - Extrasystoles is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Fit - Tonic Clonic Seizure is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Shock is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Temporary Blindness - Transient Blindness is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Benadryl and Zofran combined

Critcal Seriouosness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Benadryl and Zofran combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zofran and Benadryl combined.

Zofran and Benadryl Combined have 7 Most Frequently Occurring Side Effects

An Increase in the Thickness of Lung Secretions - Thick Bronchial Secretions is a Frequently Occurring Side Effect of Zofran and Benadryl combined

Chills is a Frequently Occurring Side Effect of Zofran and Benadryl combined

Diarrhea is a Frequently Occurring Side Effect of Zofran and Benadryl combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Zofran and Benadryl combined

Fever is a Frequently Occurring Side Effect of Zofran and Benadryl combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zofran and Benadryl combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Zofran and Benadryl combined

Click for a searchable interactive map of all Side Effects associated with Zofran and Benadryl combined.

Zofran and Benadryl Drug-Drug Interactions

There are no drug-drug interactions between Zofran and Benadryl.

Zofran has 2 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zofran.

Zofran Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Zofran.

Contraindication Warnings

Extrapyramidal Disease - Extrapyramidal Reaction is a contraindication of Zofran.

Benadryl has 9 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Benadryl.

Benadryl Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Benign Prostatic Hypertrophy - Enlarged Prostate is a contraindication of Benadryl.

Bladder Outflow Obstruction - Blockage of Urinary Bladder is a contraindication of Benadryl.

Chronic Idiopathic Constipation - Chronic Difficulty having a Bowel Movement is a contraindication of Benadryl.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Benadryl.

Stenosing Peptic Ulcer is a contraindication of Benadryl.

Urinary Retention - Cannot Empty Bladder is a contraindication of Benadryl.

Contraindication Warnings

Hypertension - High Blood Pressure is a contraindication of Benadryl.

Hyperthyroidism - Overactive Thyroid Gland is a contraindication of Benadryl.

Ocular Hypertension - Increased Pressure in the Eye is a contraindication of Benadryl.

Zofran - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Benadryl - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include large pupils, flushing, fever, hallucinations, weakness, shaking (tremor), muscle twitching, loss of consciousness, and seizures. In children, excitement may occur first, and may be followed by loss of coordination, drowsiness, loss of consciousness, and seizures.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.