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Uses of Zofran
 
Zofran is also known by the generic name Ondansetron Hcl


USES:
This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.


Uses of Compazine
 
Compazine is also known by the generic name Prochlorperazine Edisylate


Compazine is also known by the generic name Prochlorperazine Maleate


Compazine is also known by the generic name Prochlorperazine


USES:
This medication is used to treat severe nausea and vomiting from various causes (e.g., anti-cancer treatment, migraine headaches, after surgery).

Prochlorperazine is a phenothiazine medication that works by affecting the balance of natural chemicals (neurotransmitters) in the brain to reduce nausea and the urge to vomit.

This medication is not recommended for use in children under 2 years old or during surgery on children.


Zofran and Compazine Combined Have 35 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Abnormal Movements of Face Muscles and Tongue - Tardive Dyskinesia is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Blurred Vision is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Contact Dermatitis is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Continued Painful Erection - Priapism is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Dark Pigmentation of Tissues or Organs - Melanosis is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Decreased Oxygen In The Tissues Or Blood - Hypoxia is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Difficult or Painful Urination - Dysuria is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Low Body Temperature - Hypothermia is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Pigmentary Retinopathy is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Problems with Eyesight - Visual Changes is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Shock is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Sun-Sensitive Skin - Skin Photosensitivity is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Sunstroke - Heat Stroke is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Temporary Blindness - Transient Blindness is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Very Rapid Heartbeat - Torsades de Pointes - Torsades de Pointes is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Compazine and Zofran combined
Critcal Seriouosness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Compazine and Zofran combined

Zofran and Compazine Combined have 19 Most Frequently Occurring Side Effects
 
A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Frequently Occurring Side Effect of Zofran and Compazine combined
Abnormal Movements of Face Muscles and Tongue - Tardive Dyskinesia is a Frequently Occurring Side Effect of Zofran and Compazine combined
Abnormally Low Blood Pressure - Hypotension is a Frequently Occurring Side Effect of Zofran and Compazine combined
Blood Pressure Drop Upon Standing - Orthostatic Hypotension is a Frequently Occurring Side Effect of Zofran and Compazine combined
Blurred Vision is a Frequently Occurring Side Effect of Zofran and Compazine combined
Chills is a Frequently Occurring Side Effect of Zofran and Compazine combined
Decreased Sweating is a Frequently Occurring Side Effect of Zofran and Compazine combined
Diarrhea is a Frequently Occurring Side Effect of Zofran and Compazine combined
Dizzy - Dizziness is a Frequently Occurring Side Effect of Zofran and Compazine combined
Drowsiness - Drowsy is a Frequently Occurring Side Effect of Zofran and Compazine combined
Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Zofran and Compazine combined
Extrapyramidal Reaction - Extrapyramidal Disease is a Frequently Occurring Side Effect of Zofran and Compazine combined
Feeling Faint - Fainting is a Frequently Occurring Side Effect of Zofran and Compazine combined
Fever is a Frequently Occurring Side Effect of Zofran and Compazine combined
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zofran and Compazine combined
Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Zofran and Compazine combined
Increased Production of Saliva - Sialorrhea is a Frequently Occurring Side Effect of Zofran and Compazine combined
Pigmentary Retinopathy is a Frequently Occurring Side Effect of Zofran and Compazine combined
Stuffy Nose - Nasal Congestion is a Frequently Occurring Side Effect of Zofran and Compazine combined

Zofran and Compazine Drug-Drug Interactions
 
There are no drug-drug interactions between Zofran and Compazine.

Zofran has 2 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Zofran.

Zofran Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications 

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Zofran.

Contraindication Warnings 

Extrapyramidal Disease - Extrapyramidal Reaction is a contraindication of Zofran.

Compazine has 39 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Compazine.

Compazine Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Coma is a contraindication of Compazine.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Compazine.

Neuroleptic Malignant Syndrome is a contraindication of Compazine.

Severe Cardiovascular Disease - Serious Problems with Heart and Blood Vessels is a contraindication of Compazine.

Stupor is a contraindication of Compazine.

Relative Contraindications 

Breast Carcinoma - Breast Cancer is a contraindication of Compazine.

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Compazine.

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Compazine.

Disease of Liver - Liver Problems is a contraindication of Compazine.

Extrapyramidal Disease - Extrapyramidal Reaction is a contraindication of Compazine.

Glaucoma - Increased Pressure in Eyes is a contraindication of Compazine.

Metabolic Syndrome X is a contraindication of Compazine.

Myocardial Infarction - Heart Attack is a contraindication of Compazine.

Myocardial Ischemia - Disease of Inadequate Blood Flow to the Heart Muscle is a contraindication of Compazine.

Obesity - Overweight is a contraindication of Compazine.

Organophosphate Insecticide Poisoning - Insecticide Poisoning due to Organophosphate Ingredient is a contraindication of Compazine.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Compazine.

Senile Dementia - Dementia in an Elderly Person is a contraindication of Compazine.

Symptomatic Prostatic Hypertrophy - Enlarged Prostate with Urination Problems is a contraindication of Compazine.

Tardive Dyskinesia - Abnormal Movements of Face Muscles and Tongue is a contraindication of Compazine.

Torsades de Pointes - Very Rapid Heartbeat - Torsades de Pointes is a contraindication of Compazine.

Urinary Retention - Cannot Empty Bladder is a contraindication of Compazine.

Contraindication Warnings 

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Compazine.

Anemia is a contraindication of Compazine.

Angina is a contraindication of Compazine.

Bradycardia - Slow Heartbeat is a contraindication of Compazine.

Chronic Disease of Respiratory System - Chronic Lung or Breathing Passage Problem is a contraindication of Compazine.

Chronic Heart Failure is a contraindication of Compazine.

Epilepsy - Epileptic Seizure is a contraindication of Compazine.

Hyperglycemia - High Blood Sugar is a contraindication of Compazine.

Hyperprolactinemia - Increased Levels of Prolactin in the Blood is a contraindication of Compazine.

Leukopenia - Decreased White Blood Cells is a contraindication of Compazine.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Compazine.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Compazine.

Parkinsonism - Parkinson Symptoms is a contraindication of Compazine.

Predisposition to Aspiration - Susceptible to Breathing Fluid Into Lungs is a contraindication of Compazine.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Compazine.

Visual Changes - Problems with Eyesight is a contraindication of Compazine.

Weight Gain is a contraindication of Compazine.
Zofran - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Compazine - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include restlessness, muscle spasms, deep sleep/loss of consciousness, seizures, irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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