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Uses of Zofran
 
Zofran is also known by the generic name Ondansetron Hcl


USES:
This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.


Uses of Reglan
 
Reglan is also known by the generic name Metoclopramide


USES:
This medication is used to treat certain conditions of the stomach and intestines. Metoclopramide is used as a short-term treatment (4 to 12 weeks) for persistent heartburn when the usual medicines do not work well enough. It is used mostly for heartburn that occurs after a meal or during the daytime. Treating persistent heartburn can decrease the damage done by stomach acid to the swallowing tube (esophagus) and help healing.

Metoclopramide is also used in diabetic patients who have poor emptying of their stomachs (gastroparesis). Treating gastroparesis can decrease symptoms of nausea, vomiting, and stomach/abdominal fullness. Metoclopramide works by blocking a natural substance (dopamine). It speeds up stomach emptying and movement of the upper intestines.


Zofran and Reglan Combined Have 25 Life Threatening (Major) Side Effects
 
Critcal Seriouosness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Abnormal Movements of Face Muscles and Tongue - Tardive Dyskinesia is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Blurred Vision is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Decreased Oxygen In The Tissues Or Blood - Hypoxia is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Feeling Restless - Feeling Agitated is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Panic Disorder is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Parkinson Symptoms - Parkinsonism is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Shock is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Temporary Blindness - Transient Blindness is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Reglan and Zofran combined
Critcal Seriouosness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Reglan and Zofran combined

Zofran and Reglan Combined have 8 Most Frequently Occurring Side Effects
 
Chills is a Frequently Occurring Side Effect of Zofran and Reglan combined
Diarrhea is a Frequently Occurring Side Effect of Zofran and Reglan combined
Dizzy - Dizziness is a Frequently Occurring Side Effect of Zofran and Reglan combined
Drowsiness - Drowsy is a Frequently Occurring Side Effect of Zofran and Reglan combined
Fever is a Frequently Occurring Side Effect of Zofran and Reglan combined
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zofran and Reglan combined
Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Zofran and Reglan combined
Low Energy - Fatigue is a Frequently Occurring Side Effect of Zofran and Reglan combined

Zofran and Reglan Drug-Drug Interactions
 
There are no drug-drug interactions between Zofran and Reglan.

Zofran has 2 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Zofran.

Zofran Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications 

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Zofran.

Contraindication Warnings 

Extrapyramidal Disease - Extrapyramidal Reaction is a contraindication of Zofran.

Reglan has 19 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Reglan.

Reglan Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Gastrointestinal Hemorrhage - Bleeding of the Stomach or Intestines is a contraindication of Reglan.

Gastrointestinal Perforation - A Rupture in the Wall of the Stomach or Intestine is a contraindication of Reglan.

Mechanical Ileus - Mechanical Intestinal Obstruction is a contraindication of Reglan.

Neuroleptic Malignant Syndrome is a contraindication of Reglan.

Pheochromocytoma - Tumor of Adrenal Gland Causing High Blood Pressure is a contraindication of Reglan.

Seizure Disorder - Seizures is a contraindication of Reglan.

Tardive Dyskinesia - Abnormal Movements of Face Muscles and Tongue is a contraindication of Reglan.

Relative Contraindications 

Acquired Dystonia - Muscle Problems that cause Abnormal Movement is a contraindication of Reglan.

Depression is a contraindication of Reglan.

NADH Methemoglobin Reductase Deficiency - Deficiency of the Blood Enzyme Cytochrome b5 Reductase is a contraindication of Reglan.

Parkinsonism - Parkinson Symptoms is a contraindication of Reglan.

Porphyria is a contraindication of Reglan.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Reglan.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Reglan.

Contraindication Warnings 

Body Fluid Retention - Water Retention is a contraindication of Reglan.

Chronic Heart Failure is a contraindication of Reglan.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Reglan.

Hypertension - High Blood Pressure is a contraindication of Reglan.

Intestinal Anastomosis - Surgical Joining of Two Parts of the Intestine is a contraindication of Reglan.
Zofran - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Reglan - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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