Combine Zofran and Tramadol

Drug Interactions and Combined Side Effects of
Zofran

and Tramadol

Combine Zofran with Tramadol. To make a decision about taking Zofran and Tramadol, click here for a Medication Risk Map showing their individual and Combined Risks

Zofran and Tramadol have 78 combined Side Effects total
33 are Life Threatening
8 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Zofran.
Click here for Drug Interactions and Side Effects of Tramadol.
Click here to compare Zofran vs Tramadol.

Uses of Zofran

Zofran is also known by the generic name Ondansetron Hcl USES: This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.

Uses of Tramadol

USES: This medication is used to help relieve moderate to moderately severe pain. Tramadol is similar to narcotic analgesics. It works in the brain to change how your body feels and responds to pain.

Zofran and Tramadol Combined Have 33 Life Threatening (Major) Side Effects

Critcal Seriouosness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Blood Pressure Drop Upon Standing - Orthostatic Hypotension is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Blurred Vision is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Cannot Empty Bladder - Urinary Retention is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Decreased Oxygen In The Tissues Or Blood - Hypoxia is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Frequent Urination - Increased Urinary Frequency is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Involuntary Quivering - Tremors is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Loss of Memory - Memory Impairment is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Redness of Skin - Erythema is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Shock is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Small Skin Blister - Blistering Skin is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Temporary Blindness - Transient Blindness is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Tramadol and Zofran combined

Critcal Seriouosness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Tramadol and Zofran combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zofran and Tramadol combined.

Zofran and Tramadol Combined have 8 Most Frequently Occurring Side Effects

Chills is a Frequently Occurring Side Effect of Zofran and Tramadol combined

Diarrhea is a Frequently Occurring Side Effect of Zofran and Tramadol combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Zofran and Tramadol combined

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Zofran and Tramadol combined

Fever is a Frequently Occurring Side Effect of Zofran and Tramadol combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zofran and Tramadol combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Zofran and Tramadol combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Zofran and Tramadol combined

Click for a searchable interactive map of all Side Effects associated with Zofran and Tramadol combined.

Zofran and Tramadol Drug-Drug Interactions

When combined Zofran and Tramadol have the following 2 Drug-Drug Interaction(s):

When combined Zofran and Tramadol have the following interaction of Moderate seriousness: Concurrent use of ondansetron may decrease the effectiveness of tramadol, resulting in increased use of tramadol. Ondansetron may not be effective in reducing tramadol-induced nausea.

Click for a searchable interactive map of all interactions between Zofran and Tramadol.

Zofran has 2 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zofran.

Zofran Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Zofran.

Contraindication Warnings

Extrapyramidal Disease - Extrapyramidal Reaction is a contraindication of Zofran.

Tramadol has 22 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Tramadol.

Tramadol Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Alcohol Intoxication is a contraindication of Tramadol.

Benzodiazepine Toxicity - Adverse Effect of Benzodiazepine-Based Tranquilizer is a contraindication of Tramadol.

Opioid Toxicity - Toxic Amount of Narcotics in the Body is a contraindication of Tramadol.

Pregnancy is a contraindication of Tramadol.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Tramadol.

Substance Abuse - Misuse or Excessive Use of Drugs is a contraindication of Tramadol.

Suicidal is a contraindication of Tramadol.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Tramadol.

Relative Contraindications

Abrupt Drug Withdrawal Causing Life-Threatening Sequelae - Sudden Drug Withdrawal Causing Life-Threatening Reactions is a contraindication of Tramadol.

Alcohol Withdrawal Syndrome - Symptoms from Alcohol Withdrawal is a contraindication of Tramadol.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Tramadol.

CNS Depression - Abnormal Nervous System Function Affecting Mental Alertness is a contraindication of Tramadol.

Central Nervous System Infection - Nervous System Infection of Brain and Spinal Cord is a contraindication of Tramadol.

Depression is a contraindication of Tramadol.

Epilepsy - Epileptic Seizure is a contraindication of Tramadol.

Head Injury is a contraindication of Tramadol.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Tramadol.

Intracranial Hypertension - High Pressure Within the Skull is a contraindication of Tramadol.

Lower Seizure Threshold is a contraindication of Tramadol.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Tramadol.

Seizure Disorder - Seizures is a contraindication of Tramadol.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Tramadol.

Zofran - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Tramadol - Symptoms of overdose may include
slow breathing, slow/irregular heartbeat, loss of consciousness, seizure.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.