Combine Zoloft and Flexeril

Drug Interactions and Combined Side Effects of
Zoloft

and Flexeril

Combine Zoloft with Flexeril. To make a decision about taking Zoloft and Flexeril, click here for a Medication Risk Map showing their individual and Combined Risks

Zoloft and Flexeril have 74 combined Side Effects total
40 are Life Threatening
19 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Zoloft.
Click here for Drug Interactions and Side Effects of Flexeril.
Click here to compare Zoloft vs Flexeril.

Uses of Zoloft

Zoloft is also known by the generic name Sertraline

USES:
Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

Uses of Flexeril

Flexeril is also known by the generic name Cyclobenzaprine USES: This medication relaxes muscles. It is used along with rest and physical therapy to decrease muscle pain and spasms associated with strains, sprains or other muscle injuries.

Zoloft and Flexeril Combined Have 40 Life Threatening (Major) Side Effects

Critcal Seriouosness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Altered Interest in Having Sexual Intercourse - Libido Changes is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Blockage of Normal Bile Flow - Cholestasis is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Breast Tenderness - Mastalgia is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Depression is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Difficult or Painful Urination - Dysuria is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Discharge of Milk in Men or Women when Not Breastfeeding - Galactorrhea not associated with Childbirth is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Fever is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Giant Hives - Angioedema is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Heart Throbbing or Pounding - Palpitations is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Hemorrhage is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Hepatitis is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Inability to have an Erection - Erectile Dysfunction is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Mild Degree of Mania - Hypomania is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Sexual Problems - Abnormal Sexual Function is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Toxic Effect on Brain or Spinal Cord Function - CNS Toxicity is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Uncoordinated - Ataxia is a Life Threatening Side Effect of Flexeril and Zoloft combined

Critcal Seriouosness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Flexeril and Zoloft combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Flexeril combined.

Zoloft and Flexeril Combined have 19 Most Frequently Occurring Side Effects

Altered Interest in Having Sexual Intercourse - Libido Changes is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Blurred Vision is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Diarrhea is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Gas - Flatulence is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Inability to have an Erection - Erectile Dysfunction is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Low Energy - Fatigue is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Sexual Problems - Abnormal Sexual Function is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Weight Loss is a Frequently Occurring Side Effect of Zoloft and Flexeril combined

Click for a searchable interactive map of all Side Effects associated with Zoloft and Flexeril combined.

Zoloft and Flexeril Drug-Drug Interactions

When combined Zoloft and Flexeril have the following 1 Drug-Drug Interaction(s):

When combined Zoloft and Flexeril have the following interaction of Moderate seriousness: Concurrent administration of a selective serotonin reuptake inhibitor, duloxetine or milnacipran with a tricyclic compound or trazodone may result in an increase in serum levels, toxicities, and/or clinical effects of the tricyclic compound or trazodone.

Click for a searchable interactive map of all interactions between Zoloft and Flexeril.

Zoloft has 13 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zoloft.

Zoloft Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Bipolar Disorder - Manic-Depression is a contraindication of Zoloft.

Neuroleptic Malignant Syndrome is a contraindication of Zoloft.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Zoloft.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Zoloft.

Upper GI Bleed - Bleeding from Stomach, Esophagus or Duodenum is a contraindication of Zoloft.

Contraindication Warnings

Disease of Liver - Liver Problems is a contraindication of Zoloft.

Hypomania - Mild Degree of Mania is a contraindication of Zoloft.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Zoloft.

Increased Risk of Bleeding is a contraindication of Zoloft.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Zoloft.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Zoloft.

Seizure Disorder - Seizures is a contraindication of Zoloft.

Weight Loss is a contraindication of Zoloft.

Flexeril has 10 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Flexeril.

Flexeril Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Chronic Heart Failure is a contraindication of Flexeril.

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Flexeril.

Heart Block is a contraindication of Flexeril.

Hyperthyroidism - Overactive Thyroid Gland is a contraindication of Flexeril.

Recovery Phase Following Myocardial Infarct - Recent Heart Attack is a contraindication of Flexeril.

Relative Contraindications

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Flexeril.

Sinus Tachycardia is a contraindication of Flexeril.

Contraindication Warnings

Glaucoma - Increased Pressure in Eyes is a contraindication of Flexeril.

Open Angle Glaucoma - Wide-Angle Glaucoma is a contraindication of Flexeril.

Urinary Retention - Cannot Empty Bladder is a contraindication of Flexeril.

Zoloft - Symptoms of overdose may include
severe dizziness, fainting.

Flexeril - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe drowsiness, fast heartbeat, slurred speech, hallucinations, chest pain, seizures, increased muscle stiffness with fever and sweating,

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.