Combine Zoloft and Wellbutrin

Drug Interactions and Combined Side Effects of
Zoloft

and Wellbutrin

Combine Zoloft with Wellbutrin. To make a decision about taking Zoloft and Wellbutrin, click here for a Medication Risk Map showing their individual and Combined Risks

Zoloft and Wellbutrin have 81 combined Side Effects total
43 are Life Threatening
22 Occur Most Frequently

Click here for Drug Interactions and Side Effects of Zoloft.
Click here for Drug Interactions and Side Effects of Wellbutrin.
Click here to compare Zoloft vs Wellbutrin.

Uses of Zoloft

Zoloft is also known by the generic name Sertraline

USES:
Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

Uses of Wellbutrin

Wellbutrin is also known by the generic name Bupropion Hcl USES: Bupropion is used to treat depression. It can improve your mood and feelings of well-being. It may work by helping to restore the balance of certain natural chemicals (neurotransmitters) in your brain.

Zoloft and Wellbutrin Combined Have 43 Life Threatening (Major) Side Effects

Critcal Seriouosness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Altered Interest in Having Sexual Intercourse - Libido Changes is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Anxious - Anxiety is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Breast Tenderness - Mastalgia is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Cannot Focus Thoughts - Concentration Difficulty is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Chest Pain is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Confused - Impaired Cognition is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Delusions - Delusional Disorder is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Discharge of Milk in Men or Women when Not Breastfeeding - Galactorrhea not associated with Childbirth is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Feeling Faint - Fainting is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Feeling Restless - Feeling Agitated is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Fever is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Hallucination - Hallucinations is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Heart Throbbing or Pounding - Palpitations is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Hemorrhage is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Hives - Urticaria is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Inability to have an Erection - Erectile Dysfunction is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Joint Pain - Arthralgia is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Mental Disorder with Loss of Normal Personality & Reality - Psychotic Disorder is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Mild Degree of Mania - Hypomania is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Painful Periods - Dysmenorrhea is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Paranoia - Paranoid Disorder is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Rash - Skin Rash is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Ringing in the Ears - Tinnitus is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Severe Headache - Severe Headache Disorder is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Sexual Problems - Abnormal Sexual Function is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Suicidal is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Critcal Seriouosness - Thoughts of Hurting or Killing Others - Homicidal Ideation is a Life Threatening Side Effect of Wellbutrin and Zoloft combined

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Wellbutrin combined.

Zoloft and Wellbutrin Combined have 22 Most Frequently Occurring Side Effects

Altered Interest in Having Sexual Intercourse - Libido Changes is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Anxious - Anxiety is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Diarrhea is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Dizzy - Dizziness is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Feeling Restless - Feeling Agitated is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Gas - Flatulence is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Inability to have an Erection - Erectile Dysfunction is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Low Energy - Fatigue is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Sexual Problems - Abnormal Sexual Function is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Weight Loss is a Frequently Occurring Side Effect of Zoloft and Wellbutrin combined

Click for a searchable interactive map of all Side Effects associated with Zoloft and Wellbutrin combined.

Zoloft and Wellbutrin Drug-Drug Interactions

When combined Zoloft and Wellbutrin have the following 1 Drug-Drug Interaction(s):

When combined Zoloft and Wellbutrin have the following interaction of Moderate seriousness: Concurrent use of bupropion and an antidepressant may result in additive effects on the seizure threshold, increasing the risk of seizures.(1,2) Concurrent use may increase levels of and side effects from desipramine.(1,2)

Click for a searchable interactive map of all interactions between Zoloft and Wellbutrin.

Zoloft has 13 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zoloft.

Zoloft Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Bipolar Disorder - Manic-Depression is a contraindication of Zoloft.

Neuroleptic Malignant Syndrome is a contraindication of Zoloft.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Zoloft.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Zoloft.

Upper GI Bleed - Bleeding from Stomach, Esophagus or Duodenum is a contraindication of Zoloft.

Contraindication Warnings

Disease of Liver - Liver Problems is a contraindication of Zoloft.

Hypomania - Mild Degree of Mania is a contraindication of Zoloft.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Zoloft.

Increased Risk of Bleeding is a contraindication of Zoloft.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Zoloft.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Zoloft.

Seizure Disorder - Seizures is a contraindication of Zoloft.

Weight Loss is a contraindication of Zoloft.

Wellbutrin has 28 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Wellbutrin.

Wellbutrin Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Anorexia Nervosa is a contraindication of Wellbutrin.

Bulimia Nervosa - Bulimia is a contraindication of Wellbutrin.

Seizure Disorder - Seizures is a contraindication of Wellbutrin.

Seizure due to Abrupt Benzodiazepine Withdrawal - Seizure caused by Sudden Withdrawal of Benzodiazepine is a contraindication of Wellbutrin.

Seizure due to Alcohol Withdrawal - Seizure caused by Stopping Alcohol Use is a contraindication of Wellbutrin.

Relative Contraindications

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Wellbutrin.

Central Nervous System Neoplasm - Tumor of the Brain or Spinal Cord is a contraindication of Wellbutrin.

Cerebral Metastases - Spread of Cancer to the Brain is a contraindication of Wellbutrin.

Feeling Agitated - Feeling Restless is a contraindication of Wellbutrin.

Head Injury is a contraindication of Wellbutrin.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Wellbutrin.

Hostility - Feeling Anger Toward Something is a contraindication of Wellbutrin.

Lower Seizure Threshold is a contraindication of Wellbutrin.

Manic Bipolar Disorder - Manic Phase of Manic-Depression is a contraindication of Wellbutrin.

Mood Changes is a contraindication of Wellbutrin.

Opioid Dependence - Narcotic Addiction is a contraindication of Wellbutrin.

Panic Disorder is a contraindication of Wellbutrin.

Renal Disease - Kidney Disease is a contraindication of Wellbutrin.

Sedative Drug Dependence is a contraindication of Wellbutrin.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Wellbutrin.

Stimulant Drug Dependence is a contraindication of Wellbutrin.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Wellbutrin.

Uncontrolled Diabetes Mellitus - Diabetes that is Not Under Control is a contraindication of Wellbutrin.

Contraindication Warnings

Disease of Liver - Liver Problems is a contraindication of Wellbutrin.

Hypertension - High Blood Pressure is a contraindication of Wellbutrin.

Myocardial Infarction - Heart Attack is a contraindication of Wellbutrin.

Psychotic Disorder - Mental Disorder with Loss of Normal Personality & Reality is a contraindication of Wellbutrin.

Weight Loss is a contraindication of Wellbutrin.

Zoloft - Symptoms of overdose may include
severe dizziness, fainting.

Wellbutrin - Symptoms of overdose may include
seizures, hallucinations, fast or slow heart rate, loss of consciousness.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.