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Uses of Actos
 
Actos is also known by the generic name Pioglitazone


USES:
Pioglitazone is an anti-diabetic drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes (non-insulin-dependent diabetes). It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar.

Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

Pioglitazone is used either alone or in combination with other anti-diabetic medications (such as metformin or a sulfonylurea such as glyburide). This medication should not be used to treat people with type 1 diabetes (insulin-dependent diabetes).


Uses of Januvia
 
Januvia is also known by the generic name Sitagliptin


USES:
Sitagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in people with type 2 (non-insulin-dependent) diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

Sitagliptin is an anti-diabetic drug that works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes.

This medication should not be used to treat people with type 1 diabetes (insulin-dependent diabetes).


Actos and Januvia Have 0 Life Threatening (Major) Side Effects in Common
 

Actos Has 13 Life Threatening (Major) Side Effects Not Found in Januvia
 
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Weight Gain is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Decrease in the Sharpness of Vision - Reduced Visual Acuity is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Stimulation of Ovarian Function - Ovulation Stimulation is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Macular Edema - Macular Retinal Edema is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Water Retention - Body Fluid Retention is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Hepatitis is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Worsening of Chronic Heart Failure is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Broken Bone - Fractures is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Heart Failure is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Any Disease of the Teeth - Tooth Disorder is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Visible Water Retention - Edema is a Life Threatening Side Effect of Actos but not Januvia.

Januvia Has 9 Life Threatening (Major) Side Effects Not Found in Actos
 
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Inflammation of Blood Vessels in the Skin - Cutaneous Vasculitis is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Actos but not Januvia.
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Actos but not Januvia.

Actos and Januvia Have 0 Most Frequently Occurring Side Effects in Common
 

Actos Has 6 Most Frequently Occurring Side Effects Not Found in Januvia
 
Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Actos but not Januvia.
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Actos but not Januvia.
Muscle Pain - Myalgia is a Frequently Occurring Side Effect of Actos but not Januvia.
Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Frequently Occurring Side Effect of Actos but not Januvia.
Any Disease of the Teeth - Tooth Disorder is a Frequently Occurring Side Effect of Actos but not Januvia.
Sinus Irritation and Congestion - Sinusitis is a Frequently Occurring Side Effect of Actos but not Januvia.

Januvia Has 0 Most Frequently Occurring Side Effects Not Found in Januvia
 

Actos and Januvia Treat 14 Conditions in Common
 
Type 2 Diabetes Mellitus is treated by both Actos and Januvia.

Actos has 14 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Actos.

Actos Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Decompensated Heart Failure - Suddenly Serious Symptoms of Heart Failure is a contraindication of Actos.

Severe Chronic Heart Failure - Severe Heart Failure is a contraindication of Actos.

Relative Contraindications 

Chronic Heart Failure is a contraindication of Actos.

Disease of Liver - Liver Problems is a contraindication of Actos.

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Actos.

Contraindication Warnings 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Actos.

Body Fluid Retention - Water Retention is a contraindication of Actos.

Edema - Visible Water Retention is a contraindication of Actos.

Fever is a contraindication of Actos.

Fractures - Broken Bone is a contraindication of Actos.

Infection is a contraindication of Actos.

Macular Retinal Edema - Macular Edema is a contraindication of Actos.

Surgical Procedure - Recent Operation is a contraindication of Actos.

Trauma - Injury is a contraindication of Actos.

Januvia has 6 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Januvia.

Januvia Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Januvia.

Relative Contraindications 

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Januvia.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Januvia.

Contraindication Warnings 

High Fever >101 Degrees Fahrenheit - Body Temperature More Than 101 Degrees F is a contraindication of Januvia.

Surgical Procedure - Recent Operation is a contraindication of Januvia.

Trauma - Injury is a contraindication of Januvia.
Actos - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Januvia - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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