Compare Cymbalta vs Zoloft

Compare Cymbalta

vs Zoloft

Compare Cymbalta to Zoloft. To make a decision about Cymbalta vs Zoloft, click here for a Medication Risk Map to help you select Cymbalta or Zoloft

Click here for Drug Interactions and Side Effects of Cymbalta.
Click here for Drug Interactions and Side Effects of Zoloft.
Click here to see the effects of combining Cymbalta and Zoloft.

Uses of Cymbalta

Cymbalta is also known by the generic name Duloxetine

USES:
Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).

Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.

Uses of Zoloft

Zoloft is also known by the generic name Sertraline

USES:
Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

Cymbalta and Zoloft Have 8 Life Threatening (Major) Side Effects in Common

Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of both Cymbalta and Zoloft.

Critical Seriousness - Hemorrhage is a Life Threatening Side Effect of both Cymbalta and Zoloft.

Critical Seriousness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of both Cymbalta and Zoloft.

Critical Seriousness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of both Cymbalta and Zoloft.

Critical Seriousness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of both Cymbalta and Zoloft.

Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of both Cymbalta and Zoloft.

Critical Seriousness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of both Cymbalta and Zoloft.

Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of both Cymbalta and Zoloft.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Cymbalta and Zoloft.

Cymbalta Has 17 Life Threatening (Major) Side Effects Not Found in Zoloft

Critical Seriousness - Suicidal is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Syndrome of Inappropriate Antidiuretic Hormone Secretion - SIADH Syndrome is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Redness of Skin - Erythema is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Hemorrhage of Blood Under the Skin - Ecchymosis is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Red Blood in Bowel Movement - Bloody Stools is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Feeling Faint - Fainting is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Hepatitis is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Bruise - Bruising is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Mood Changes is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Burning Stomach - Gastritis is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Needing to Urinate Immediately - Urinary Urgency is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Cymbalta and Zoloft.

Zoloft Has 17 Life Threatening (Major) Side Effects Not Found in Cymbalta

Critical Seriousness - Sexual Problems - Abnormal Sexual Function is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Heart Throbbing or Pounding - Palpitations is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Mild Degree of Mania - Hypomania is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Fever is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Discharge of Milk in Men or Women when Not Breastfeeding - Galactorrhea not associated with Childbirth is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Altered Interest in Having Sexual Intercourse - Libido Changes is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Inability to have an Erection - Erectile Dysfunction is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Critical Seriousness - Breast Tenderness - Mastalgia is a Life Threatening Side Effect of Cymbalta but not Zoloft.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Cymbalta and Zoloft.

Cymbalta and Zoloft Have 8 Most Frequently Occurring Side Effects in Common

Dizzy - Dizziness is a Frequently Occurring Side Effect of both Cymbalta and Zoloft.

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of both Cymbalta and Zoloft.

Drowsiness - Drowsy is a Frequently Occurring Side Effect of both Cymbalta and Zoloft.

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of both Cymbalta and Zoloft.

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of both Cymbalta and Zoloft.

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of both Cymbalta and Zoloft.

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of both Cymbalta and Zoloft.

Low Energy - Fatigue is a Frequently Occurring Side Effect of both Cymbalta and Zoloft.

Click for a searchable interactive map of all Side Effects associated with Cymbalta and Zoloft.

Cymbalta Has 1 Most Frequently Occurring Side Effects Not Found in Zoloft

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Cymbalta but not Zoloft. Click for a searchable interactive map of all Side Effects associated with Cymbalta and Zoloft.

Zoloft Has 10 Most Frequently Occurring Side Effects Not Found in Zoloft

Sexual Problems - Abnormal Sexual Function is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Gas - Flatulence is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Diarrhea is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Altered Interest in Having Sexual Intercourse - Libido Changes is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Inability to have an Erection - Erectile Dysfunction is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Weight Loss is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Zoloft but not Cymbalta.

Click for a searchable interactive map of all Side Effects associated with Cymbalta and Zoloft.

Cymbalta and Zoloft Treat 0 Conditions in Common

Cymbalta has 25 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Cymbalta.

Cymbalta Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Neuroleptic Malignant Syndrome is a contraindication of Cymbalta.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Cymbalta.

Relative Contraindications

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Cymbalta.

Alcoholic Liver Damage - Hardening of the Liver caused by Alcohol is a contraindication of Cymbalta.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Cymbalta.

Chronic Hepatitis - Chronic Inflammation of the Liver is a contraindication of Cymbalta.

Disease of Liver - Liver Problems is a contraindication of Cymbalta.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Cymbalta.

Hepatitis is a contraindication of Cymbalta.

Jaundice - Yellowing of Skin or Eyes from Liver Problems is a contraindication of Cymbalta.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Cymbalta.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Cymbalta.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Cymbalta.

Contraindication Warnings

Bipolar Disorder - Manic-Depression is a contraindication of Cymbalta.

Epilepsy - Epileptic Seizure is a contraindication of Cymbalta.

Gastrointestinal Hypomotility - Decreased Motility Function of Stomach or Intestines is a contraindication of Cymbalta.

Hyperglycemia - High Blood Sugar is a contraindication of Cymbalta.

Hypertension - High Blood Pressure is a contraindication of Cymbalta.

Hypomania - Mild Degree of Mania is a contraindication of Cymbalta.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Cymbalta.

Increased Risk of Bleeding is a contraindication of Cymbalta.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Cymbalta.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Cymbalta.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Cymbalta.

Urinary Retention - Cannot Empty Bladder is a contraindication of Cymbalta.

Zoloft has 13 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zoloft.

Zoloft Oral Contraindications
(grouped by decreasing seriouosness level)

Relative Contraindications

Bipolar Disorder - Manic-Depression is a contraindication of Zoloft.

Neuroleptic Malignant Syndrome is a contraindication of Zoloft.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Zoloft.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Zoloft.

Upper GI Bleed - Bleeding from Stomach, Esophagus or Duodenum is a contraindication of Zoloft.

Contraindication Warnings

Disease of Liver - Liver Problems is a contraindication of Zoloft.

Hypomania - Mild Degree of Mania is a contraindication of Zoloft.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Zoloft.

Increased Risk of Bleeding is a contraindication of Zoloft.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Zoloft.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Zoloft.

Seizure Disorder - Seizures is a contraindication of Zoloft.

Weight Loss is a contraindication of Zoloft.

Cymbalta - Symptoms of overdose may include
severe drowsiness, fainting.

Zoloft - Symptoms of overdose may include
severe dizziness, fainting.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.