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Uses of Evista
 
Evista is also known by the generic name Raloxifene


USES:
Raloxifene is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowing bone loss helps to reduce the risk of fractures.

Raloxifene may also lower the chance of getting a certain type of breast cancer (invasive) in women after menopause.

This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body. Raloxifene helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes.

This medication is not recommended for use in women before menopause. It should not be used in children.

This medication should not be used to prevent heart disease.


Uses of Tamoxifen
 
USES:
Tamoxifen is used to treat breast cancer that has spread to other parts of the body (metastatic breast cancer), to treat breast cancer in certain patients after surgery and radiation therapy, and to reduce the chances of breast cancer in high-risk patients.

This medication can block the growth of breast cancer. It works by interfering with the effects of estrogen in the breast tissue.


Evista and Tamoxifen Have 4 Life Threatening (Major) Side Effects in Common
 
Critical Seriousness - Blood Clot - Thrombotic Disorder is a Life Threatening Side Effect of both Evista and Tamoxifen.
Critical Seriousness - Stroke - Cerebrovascular Accident is a Life Threatening Side Effect of both Evista and Tamoxifen.
Critical Seriousness - Blood Clot in Lung - Pulmonary Thromboembolism is a Life Threatening Side Effect of both Evista and Tamoxifen.
Critical Seriousness - Obstruction of a Blood Vessel by a Blood Clot - Thromboembolic Disorder is a Life Threatening Side Effect of both Evista and Tamoxifen.

Evista Has 19 Life Threatening (Major) Side Effects Not Found in Tamoxifen
 
Critical Seriousness - Blood Clot in a Deep Vein - Deep Venous Thrombosis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Throat Irritation - Pharyngitis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Leg Cramps - Cramps in Legs is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Pneumonia is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Flu-Like Symptoms is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Infection is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Migraine Headache - Migraine is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - A Blood Clot within the Blood Vessels of the Eye - Retinal Thrombosis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Inflammation of the Bladder - Cystitis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Inflammation or Infection of Vagina - Vaginitis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Inflammation of the Voice Box - Laryngitis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Fever is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Gallstones - Biliary Calculus is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Chest Pain is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Inflammation of the Lining of the Stomach and Intestines - Gastroenteritis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Sinus Irritation and Congestion - Sinusitis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Urinary Tract Infection - Urinary Tract Infections is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Evista but not Tamoxifen.

Tamoxifen Has 19 Life Threatening (Major) Side Effects Not Found in Evista
 
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Disease of the Cornea of the Eye - Disorder of Cornea is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Interstitial Pneumonitis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Erythema Multiforme is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Drowsiness - Drowsy is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Cataracts is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Feeling Weak - General Weakness is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Polyps of the Lining of the Uterus or the Endometrium - Endometrial Polyps is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Disease of the Retina of the Eye - Retinal Disorder is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Cancer in the Lining of the Uterus - Endometrial Carcinoma is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Sudden Blindness and Pain Upon Moving the Eye - Optic Neuritis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Bullous Pemphigoid is a Life Threatening Side Effect of Evista but not Tamoxifen.
Critical Seriousness - Overgrowth of the Uterine Lining - Endometrial Hyperplasia is a Life Threatening Side Effect of Evista but not Tamoxifen.

Evista and Tamoxifen Have 0 Most Frequently Occurring Side Effects in Common
 

Evista Has 13 Most Frequently Occurring Side Effects Not Found in Tamoxifen
 
Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Leg Cramps - Cramps in Legs is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Flu-Like Symptoms is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Infection is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Inflammation of the Bladder - Cystitis is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Inflammation or Infection of Vagina - Vaginitis is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
"Change of Life" Signs - Vasomotor Symptoms associated with Menopause is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Fever is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Chest Pain is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Sinus Irritation and Congestion - Sinusitis is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Urinary Tract Infection - Urinary Tract Infections is a Frequently Occurring Side Effect of Evista but not Tamoxifen.
Rash - Skin Rash is a Frequently Occurring Side Effect of Evista but not Tamoxifen.

Tamoxifen Has 0 Most Frequently Occurring Side Effects Not Found in Tamoxifen
 

Evista and Tamoxifen Treat 1 Conditions in Common
 
Prevention of Breast Cancer - Prevention of Breast Carcinoma is treated by both Evista and Tamoxifen.

Evista has 19 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Evista.

Evista Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Deep Venous Thrombosis - Blood Clot in a Deep Vein is a contraindication of Evista.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Evista.

Pregnancy is a contraindication of Evista.

Pulmonary Thromboembolism - Blood Clot in Lung is a contraindication of Evista.

Retinal Thrombosis - A Blood Clot within the Blood Vessels of the Eye is a contraindication of Evista.

Relative Contraindications 

Atrial Fibrillation is a contraindication of Evista.

Cerebrovascular Accident - Stroke is a contraindication of Evista.

Chronic Heart Failure is a contraindication of Evista.

Coronary Artery Disease - Disease of the Arteries of the Heart is a contraindication of Evista.

Hypercoagulability States - Abnormal Increase in Ability of Blood to Clot is a contraindication of Evista.

Hypertension - High Blood Pressure is a contraindication of Evista.

Increased Cardiovascular Event Risk is a contraindication of Evista.

Lupus Anticoagulant Disorder is a contraindication of Evista.

Thrombophlebitis - Blood Clot in Vein is a contraindication of Evista.

Tobacco Smoker - Tobacco Smoking is a contraindication of Evista.

Transient Cerebral Ischemia - Transient Ischemic Attack is a contraindication of Evista.

Contraindication Warnings 

Disease of Liver - Liver Problems is a contraindication of Evista.

Hypertriglyceridemia - High Amount of Triglyceride in the Blood is a contraindication of Evista.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Evista.

Tamoxifen has 11 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Tamoxifen.

Tamoxifen Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Deep Venous Thrombosis - Blood Clot in a Deep Vein is a contraindication of Tamoxifen.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Tamoxifen.

Pregnancy is a contraindication of Tamoxifen.

Relative Contraindications 

Cerebrovascular Accident - Stroke is a contraindication of Tamoxifen.

Pulmonary Thromboembolism - Blood Clot in Lung is a contraindication of Tamoxifen.

Severe Thrombocytopenia - Severely Decreased Platelets is a contraindication of Tamoxifen.

Thromboembolic Disorder - Obstruction of a Blood Vessel by a Blood Clot is a contraindication of Tamoxifen.

Contraindication Warnings 

Cataracts is a contraindication of Tamoxifen.

Hypercalcemia - High Amount of Calcium in the Blood is a contraindication of Tamoxifen.

Leukopenia - Decreased White Blood Cells is a contraindication of Tamoxifen.

Visual Changes - Problems with Eyesight is a contraindication of Tamoxifen.
Evista - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Tamoxifen - Symptoms of overdose may include
shaking, unsteady walking, fainting, irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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