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Compare Januvia  vs Metformin
Uses of Januvia |
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| | Januvia is also known by the generic name Sitagliptin
USES:
Sitagliptin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in people with type 2 (non-insulin-dependent) diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.
Sitagliptin is an anti-diabetic drug that works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes.
This medication should not be used to treat people with type 1 diabetes (insulin-dependent diabetes).
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Uses of Metformin |
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| | USES:
Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes (non-insulin-dependent diabetes). Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.
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Januvia and Metformin Have 1 Life Threatening (Major) Side Effects in Common |
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| | Critical Seriousness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of both Januvia and Metformin. |
Januvia Has 8 Life Threatening (Major) Side Effects Not Found in Metformin |
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| | Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Januvia but not Metformin. Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Januvia but not Metformin. Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Januvia but not Metformin. Critical Seriousness - Inflammation of Blood Vessels in the Skin - Cutaneous Vasculitis is a Life Threatening Side Effect of Januvia but not Metformin. Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Januvia but not Metformin. Critical Seriousness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Januvia but not Metformin. Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Januvia but not Metformin. Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Januvia but not Metformin. |
Metformin Has 3 Life Threatening (Major) Side Effects Not Found in Januvia |
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| | Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Januvia but not Metformin. Critical Seriousness - Megaloblastic Anemia is a Life Threatening Side Effect of Januvia but not Metformin. Critical Seriousness - Increased Blood Acidity due to High Levels of Lactic Acid - Lactic Acidosis is a Life Threatening Side Effect of Januvia but not Metformin. |
Januvia and Metformin Have 0 Most Frequently Occurring Side Effects in Common |
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Januvia Has 0 Most Frequently Occurring Side Effects Not Found in Metformin |
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Metformin Has 9 Most Frequently Occurring Side Effects Not Found in Metformin |
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| | Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Metformin but not Januvia. Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Metformin but not Januvia. Swelling of the Abdomen - Abdominal Swelling is a Frequently Occurring Side Effect of Metformin but not Januvia. Taste Problems - Dysgeusia is a Frequently Occurring Side Effect of Metformin but not Januvia. Throwing Up - Vomiting is a Frequently Occurring Side Effect of Metformin but not Januvia. Gas - Flatulence is a Frequently Occurring Side Effect of Metformin but not Januvia. Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Frequently Occurring Side Effect of Metformin but not Januvia. Diarrhea is a Frequently Occurring Side Effect of Metformin but not Januvia. Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Metformin but not Januvia. |
Januvia and Metformin Treat 14 Conditions in Common |
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| | Type 2 Diabetes Mellitus is treated by both Januvia and Metformin. |
Januvia has 6 Condition Contraindications |
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| | If you have any of these Conditions then you should carefully evaluate the risks of taking Januvia.
Januvia Oral Contraindications
(grouped by decreasing seriousness level)
Absolute Contraindications 
Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Januvia.
Relative Contraindications
Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Januvia.
Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Januvia.
Contraindication Warnings
High Fever >101 Degrees Fahrenheit - Body Temperature More Than 101 Degrees F is a contraindication of Januvia.
Surgical Procedure - Recent Operation is a contraindication of Januvia.
Trauma - Injury is a contraindication of Januvia. |
Metformin has 26 Condition Contraindications |
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| | If you have any of these Conditions then you should carefully evaluate the risks of taking Metformin.
Metformin Oral Contraindications
(grouped by decreasing seriouosness level)
Absolute Contraindications
Acute Decompensated Heart Failure - Suddenly Serious Symptoms of Heart Failure is a contraindication of Metformin.
Alcohol Intoxication is a contraindication of Metformin.
Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Metformin.
Cardiogenic Shock - Blood Circulation Failure due to Serious Heart Condition is a contraindication of Metformin.
Dehydration - Extreme Loss of Body Water is a contraindication of Metformin.
Disease of Liver - Liver Problems is a contraindication of Metformin.
Ketoacidosis is a contraindication of Metformin.
Lactic Acidosis - Increased Blood Acidity due to High Levels of Lactic Acid is a contraindication of Metformin.
Metabolic Acidosis - Excess Body Acid is a contraindication of Metformin.
Myocardial Infarction - Heart Attack is a contraindication of Metformin.
Radiography with IV Iodinated Contrast Agent - X-Ray Study with Intravenous Iodine Contrast Agent is a contraindication of Metformin.
Renal Disease - Kidney Disease is a contraindication of Metformin.
Sepsis Syndrome is a contraindication of Metformin.
Severe Hypoxemia - Serious Lack of Oxygen in the Blood is a contraindication of Metformin.
Shock is a contraindication of Metformin.
Surgical Procedure - Recent Operation is a contraindication of Metformin.
Trauma - Injury is a contraindication of Metformin.
Relative Contraindications
Adrenocortical Insufficiency - Decreased Function of the Adrenal Gland is a contraindication of Metformin.
Debilitation - Weakened Patient is a contraindication of Metformin.
Fever is a contraindication of Metformin.
Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Metformin.
Infection is a contraindication of Metformin.
Pituitary Insufficiency - Pituitary Hormone Deficiency is a contraindication of Metformin.
Severe Diarrhea is a contraindication of Metformin.
Severe Vomiting is a contraindication of Metformin.
Contraindication Warnings
Vitamin B12 Deficiency - Inadequate Vitamin B12 is a contraindication of Metformin. |
Januvia - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.
Metformin - Symptoms of overdose may include
severe drowsiness, severe nausea/vomiting/diarrhea, rapid breathing, slow/irregular heartbeat.
Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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