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Uses of Plavix
 
Plavix is also known by the generic name Clopidogrel


USES:
Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease).

It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent, coronary artery bypass graft-CABG, balloon angioplasty).

It works by blocking certain blood cells called platelets and prevents them from forming harmful blood clots. This "anti-platelet" effect helps keep blood flowing smoothly in your body.


Uses of Warfarin
 
USES:
This medication is used to treat blood clots (such as in deep vein thrombosis-DVT or pulmonary embolus-PE) and/or to prevent new clots from forming in your body. Preventing harmful blood clots helps to reduce the risk of a stroke or heart attack. Conditions that increase your risk of developing blood clots include a certain type of irregular heart rhythm (atrial fibrillation), heart valve replacement, recent heart attack, and certain surgeries (such as hip/knee replacement).

Warfarin is commonly called a "blood thinner," but the more correct term is "anticoagulant." It helps to keep blood flowing smoothly in your body by decreasing the amount of certain substances (clotting proteins) in your blood.


Plavix and Warfarin Have 10 Life Threatening (Major) Side Effects in Common
 
Critical Seriousness - Bloody Urine - Hematuria is a Life Threatening Side Effect of both Plavix and Warfarin.
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of both Plavix and Warfarin.
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of both Plavix and Warfarin.
Critical Seriousness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of both Plavix and Warfarin.
Critical Seriousness - Hemorrhage is a Life Threatening Side Effect of both Plavix and Warfarin.
Critical Seriousness - Throwing Up - Vomiting is a Life Threatening Side Effect of both Plavix and Warfarin.
Critical Seriousness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of both Plavix and Warfarin.
Critical Seriousness - Vasculitis is a Life Threatening Side Effect of both Plavix and Warfarin.
Critical Seriousness - Pancreatitis is a Life Threatening Side Effect of both Plavix and Warfarin.
Critical Seriousness - Kidney Disease - Renal Disease is a Life Threatening Side Effect of both Plavix and Warfarin.

Plavix Has 30 Life Threatening (Major) Side Effects Not Found in Warfarin
 
Critical Seriousness - Acquired Decrease of All Cells in the Blood - Pancytopenia is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Low Blood Counts due to Bone Marrow Failure - Aplastic Anemia is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Hemorrhage from the Conjunctiva of the Eye - Conjunctival Hemorrhage is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Hemorrhage Within the Skull - Intracranial Bleeding is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Inflammation of the Large Intestine - Colitis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Hallucination - Hallucinations is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Interstitial Pneumonitis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Erythema Multiforme is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Allergic Reaction causing Serum Sickness - Serum Sickness is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Bleeding from Wound is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Thrombotic Thrombocytopenic Purpura is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Painful, Red or Swollen Mouth - Stomatitis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Hepatitis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Inflammation of the Skin with Blisters - Bullous Dermatitis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Eye Hemorrhage - Ocular Bleeding is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Retinal Hemorrhage is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Ulcer of the Duodenum - Duodenal Ulcer is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Bleeding in the Abdomen - Retroperitoneal Hemorrhage is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Bleeding from the Respiratory Tract - Respiratory Tract Hemorrhage is a Life Threatening Side Effect of Plavix but not Warfarin.

Warfarin Has 26 Life Threatening (Major) Side Effects Not Found in Plavix
 
Critical Seriousness - Problem with Adrenal Gland - Acute Adrenocortical Insufficiency is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Ulcer of the Throat - Throat Ulceration is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Feel Like Throwing Up - Nausea is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Adrenal Hemorrhage is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Increased Risk of Bleeding is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Obstruction of Blood Vessel caused by a Fat Globule - Cholesterol Embolism is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Canker Sore - Aphthous Stomatitis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Muscle Pain - Myalgia is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Pain in Arms or Legs - Limb Pain is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Foot Pain - Feet Pain is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Diarrhea is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Inflammation of the Liver with Stoppage of Bile Flow - Cholestatic Hepatitis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Visible Water Retention - Edema is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Lack of Blood Supply to the Brain - Cerebral Ischemia is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Purplish Discoloration of the Skin that Looks Like Netting - Livedo Reticularis is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Gangrene is a Life Threatening Side Effect of Plavix but not Warfarin.
Critical Seriousness - Tissue Death - Tissue Necrosis is a Life Threatening Side Effect of Plavix but not Warfarin.

Plavix and Warfarin Have 0 Most Frequently Occurring Side Effects in Common
 

Plavix Has 2 Most Frequently Occurring Side Effects Not Found in Warfarin
 
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Plavix but not Warfarin.
Joint Pain - Arthralgia is a Frequently Occurring Side Effect of Plavix but not Warfarin.

Warfarin Has 0 Most Frequently Occurring Side Effects Not Found in Warfarin
 

Plavix and Warfarin Treat 2 Conditions in Common
 
Prevention for a Blood Clot going to the Brain - Cerebral Thromboembolism Prevention is treated by both Plavix and Warfarin.
Myocardial Reinfarction Prevention is treated by both Plavix and Warfarin.

Plavix has 12 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Plavix.

Plavix Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Hemorrhage is a contraindication of Plavix.

Gastrointestinal Hemorrhage - Bleeding of the Stomach or Intestines is a contraindication of Plavix.

Intracranial Bleeding - Hemorrhage Within the Skull is a contraindication of Plavix.

Relative Contraindications 

Blood Coagulation Disorder - Blood Clotting Disorder is a contraindication of Plavix.

Gastrointestinal Ulcer - Stomach or Intestinal Ulcer is a contraindication of Plavix.

Poor Metabolizer due to Cytochrome p450 CYP2C19 Variant is a contraindication of Plavix.

Retinal Hemorrhage is a contraindication of Plavix.

Surgical Procedure - Recent Operation is a contraindication of Plavix.

Thrombotic Thrombocytopenic Purpura is a contraindication of Plavix.

Contraindication Warnings 

Increased Risk of Bleeding is a contraindication of Plavix.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Plavix.

Trauma - Injury is a contraindication of Plavix.

Warfarin has 60 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Warfarin.

Warfarin Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Aortic Aneurysm with Dissection - Bulge and Tear of the Aorta Blood Vessel Wall is a contraindication of Warfarin.

Bacterial Endocarditis - Bacterial Infection of Heart Valve is a contraindication of Warfarin.

Blood Coagulation Disorder - Blood Clotting Disorder is a contraindication of Warfarin.

Brain Aneurysm - Balloon-Like Swelling of an Artery of the Brain is a contraindication of Warfarin.

Cerebrovascular Hemorrhage - Hemorrhage in the Brain is a contraindication of Warfarin.

Eclampsia of Pregnancy - Seizures with Pregnancy is a contraindication of Warfarin.

Gastrointestinal Hemorrhage - Bleeding of the Stomach or Intestines is a contraindication of Warfarin.

Gastrointestinal Ulcer - Stomach or Intestinal Ulcer is a contraindication of Warfarin.

Genitourinary Tract Hemorrhage - Bleeding from the Genitourinary System is a contraindication of Warfarin.

Hemorrhage is a contraindication of Warfarin.

Internal Hemorrhage - Internal Bleeding is a contraindication of Warfarin.

Open Procedure on Central Nervous System - Operation on the Nervous System is a contraindication of Warfarin.

Pericardial Effusion - Fluid in the Covering of the Heart or Pericardium is a contraindication of Warfarin.

Pericarditis - Inflammation of the Covering of the Heart or Pericardium is a contraindication of Warfarin.

Pregnancy is a contraindication of Warfarin.

Respiratory Tract Hemorrhage - Bleeding from the Respiratory Tract is a contraindication of Warfarin.

Severe Uncontrolled Hypertension - Severe Uncontrolled High Blood Pressure is a contraindication of Warfarin.

Spinal Anesthesia - Local Anesthesia Injected into Spine is a contraindication of Warfarin.

Spinal Puncture - Spinal Tap is a contraindication of Warfarin.

Surgical Procedure on Eye Proper - Eye Surgery is a contraindication of Warfarin.

Threatened Abortion - Possibility of Having a Miscarriage is a contraindication of Warfarin.

Relative Contraindications 

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Warfarin.

Cerebrovascular Disorder - Any Disorder of the Blood Vessels of the Brain is a contraindication of Warfarin.

Cholesterol Embolism - Obstruction of Blood Vessel caused by a Fat Globule is a contraindication of Warfarin.

Gangrene is a contraindication of Warfarin.

Heparin-Induced Thrombocytopenia - Decreased Platelets due to the Medication Heparin is a contraindication of Warfarin.

Increased Risk of Bleeding is a contraindication of Warfarin.

Indwelling Vascular Catheter - Patient with Catheter in the Vascular System is a contraindication of Warfarin.

Moderate Hypertension - Moderate High Blood Pressure is a contraindication of Warfarin.

Polycythemia Vera - Increased Red Blood Cells is a contraindication of Warfarin.

Protein C Deficiency Disease is a contraindication of Warfarin.

Psychotic Disorder - Mental Disorder with Loss of Normal Personality & Reality is a contraindication of Warfarin.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Warfarin.

Secondary Uterine Inertia is a contraindication of Warfarin.

Severe Diabetes Mellitus - Severe Form of Diabetes is a contraindication of Warfarin.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Warfarin.

Severe and Chronic Diarrhea - Serious Loose Stools Lasting a Long Time is a contraindication of Warfarin.

Surgical Procedure - Recent Operation is a contraindication of Warfarin.

Tissue Necrosis - Tissue Death is a contraindication of Warfarin.

Trauma - Injury is a contraindication of Warfarin.

Tropical Sprue is a contraindication of Warfarin.

Vasculitis is a contraindication of Warfarin.

Vitamin K Deficiency - Inadequate Vitamin K is a contraindication of Warfarin.

Contraindication Warnings 

Anemia is a contraindication of Warfarin.

Biliary Obstruction - Blockage of a Bile Duct is a contraindication of Warfarin.

Bleeding Risk Associated with Vitamin-K-Epoxide Reductase (Warfarin-Sensitive) Gene is a contraindication of Warfarin.

Connective Tissue Disease - Disorder of the Connective Tissue is a contraindication of Warfarin.

Disease of Liver - Liver Problems is a contraindication of Warfarin.

Edema - Visible Water Retention is a contraindication of Warfarin.

Fever is a contraindication of Warfarin.

Hyperlipidemia - High Amount of Fats in the Blood is a contraindication of Warfarin.

Hyperthyroidism - Overactive Thyroid Gland is a contraindication of Warfarin.

Hypothyroidism - Underactive Thyroid is a contraindication of Warfarin.

Malignancy - Malignant Tumor or Cancer is a contraindication of Warfarin.

Nephrotic Syndrome is a contraindication of Warfarin.

Nutritional Disorder - Poor Nutrition is a contraindication of Warfarin.

Poor Metabolizer due to Cytochrome p450 CYP2C9 Variant is a contraindication of Warfarin.

Severe Diarrhea is a contraindication of Warfarin.

Steatorrhea - Bowel Movements Containing Much Fat is a contraindication of Warfarin.

Viral Hepatitis - Viral Infection of the Liver is a contraindication of Warfarin.
Plavix - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Warfarin - Symptoms of overdose may include
bloody/black/tarry stools, pink/dark urine, unusual/prolonged bleeding.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

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