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Uses of Protonix
 
Protonix is also known by the generic name Pantoprazole


USES:
Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux). It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Pantoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).


Uses of Nexium
 
Nexium is also known by the generic name Esomeprazole Magnesium


USES:
Esomeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Esomeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).


Protonix and Nexium Have 14 Life Threatening (Major) Side Effects in Common
 
Critical Seriousness - Acquired Decrease of All Cells in the Blood - Pancytopenia is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Depression is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Erythema Multiforme is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Interstitial Nephritis is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Broken Bone - Fractures is a Life Threatening Side Effect of both Protonix and Nexium.
Critical Seriousness - Inflammation of the Lining of the Stomach and Intestines - Gastroenteritis is a Life Threatening Side Effect of both Protonix and Nexium.

Protonix Has 15 Life Threatening (Major) Side Effects Not Found in Nexium
 
Critical Seriousness - Bloody Urine - Hematuria is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Disease of the Optic Nerve - Optic Neuropathy is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Sensitive to Light - Photophobia is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - High Blood Sugar - Hyperglycemia is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - High Amount of Fats in the Blood - Hyperlipidemia is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Skin Rash with Sloughing - Exfoliative Dermatitis is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Difficulty Speaking - Dysarthria is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Inability to have an Erection - Erectile Dysfunction is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Chest Pain is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Discolored Spots and Small Elevations of the Skin - Maculopapular Rash is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Increased Eosinophils in the Blood - Eosinophilia is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Urinary Tract Infection - Urinary Tract Infections is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Serious Muscle Damage that may Lead to Kidney Failure - Rhabdomyolysis is a Life Threatening Side Effect of Protonix but not Nexium.

Nexium Has 21 Life Threatening (Major) Side Effects Not Found in Protonix
 
Critical Seriousness - Enlarged Thyroid Gland - Goiter is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Anemia is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Muscle Weakness is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Hallucination - Hallucinations is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Blurred Vision is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Feeling Restless - Feeling Agitated is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Muscle Pain - Myalgia is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Infection due to the Candida Fungus - Candidiasis is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Painful, Red or Swollen Mouth - Stomatitis is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Hepatitis is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Aggressive Behavior is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Sinus Irritation and Congestion - Sinusitis is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Unconsciousness Resulting from Liver Cell Deterioration - Hepatic Coma is a Life Threatening Side Effect of Protonix but not Nexium.
Critical Seriousness - Atrophic Gastritis is a Life Threatening Side Effect of Protonix but not Nexium.

Protonix and Nexium Have 2 Most Frequently Occurring Side Effects in Common
 
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of both Protonix and Nexium.
Diarrhea is a Frequently Occurring Side Effect of both Protonix and Nexium.

Protonix Has 0 Most Frequently Occurring Side Effects Not Found in Nexium
 

Nexium Has 1 Most Frequently Occurring Side Effects Not Found in Nexium
 
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Nexium but not Protonix.

Protonix and Nexium Treat 13 Conditions in Common
 
Bleeding from Stomach, Esophagus or Duodenum - Upper GI Bleed is treated by both Protonix and Nexium.
Zollinger-Ellison Syndrome is treated by both Protonix and Nexium.
Inflammation of the Esophagus with Erosion - Erosive Esophagitis is treated by both Protonix and Nexium.
Stomach Ulcer from Aspirin/Ibuprofen-Like Drugs Prevention - Prevention of NSAID-Induced Gastric Ulcer is treated by both Protonix and Nexium.
Ulcer of Duodenum caused by Bacteria Helicobacter Pylori - Duodenal Ulcer due to H. Pylori is treated by both Protonix and Nexium.
Condition in which Stomach Acid is Pushed Into the Esophagus - Gastroesophageal Reflux is treated by both Protonix and Nexium.
Medication Treatment for Healing Erosive Esophagitis - Maintenance of Healing Erosive Esophagitis is treated by both Protonix and Nexium.

Protonix has 4 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Protonix.

Protonix Oral Contraindications
(grouped by decreasing seriousness level)

Contraindication Warnings 

Fractures - Broken Bone is a contraindication of Protonix.

Hypomagnesemia - Low Amount of Magnesium in the Blood is a contraindication of Protonix.

Osteoporosis is a contraindication of Protonix.

Pernicious Anemia - Anemia caused by Vitamin B12 Deficiency-Pernicious Anemia is a contraindication of Protonix.

Nexium has 5 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Nexium.

Nexium Oral Contraindications
(grouped by decreasing seriouosness level)

Relative Contraindications 

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Nexium.

Contraindication Warnings 

Atrophic Gastritis is a contraindication of Nexium.

Fractures - Broken Bone is a contraindication of Nexium.

Hypomagnesemia - Low Amount of Magnesium in the Blood is a contraindication of Nexium.

Osteoporosis is a contraindication of Nexium.
Protonix - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Nexium - Symptoms of overdose may include
confusion, extreme sweating, blurred vision, or unusually fast heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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