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Uses of Provigil
 
Provigil is also known by the generic name Modafinil


USES:
Modafinil decreases extreme sleepiness due to narcolepsy and other sleep disorders such as difficult/irregular breathing during sleep (e.g., obstructive sleep apnea/hypopnea syndrome-OSAHS). It is also used to help you stay awake during work hours for people with work schedules that interfere with a normal sleep routine (shift work sleep disorder-SWSD).

It is not known how modafinil works to increase wakefulness. It is thought to work by affecting certain chemicals in the brain that control the sleep/wake cycle. Modafinil does not make up for lack of sleep and should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder.

This medication is not recommended for use in children.


Uses of Nuvigil
 
Nuvigil is also known by the generic name Armodafinil


USES:
Armodafinil decreases extreme sleepiness due to narcolepsy and other sleep disorders such as difficult/irregular breathing during sleep (e.g., obstructive sleep apnea/hypopnea syndrome-OSAHS). It is also used to decrease sleepiness due to work schedules that interfere with a normal sleep routine (shift work sleep disorder-SWSD).

It is not known how armodafinil works to increase wakefulness. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle. Armodafinil does not make up for lack of sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder.


Provigil and Nuvigil Have 16 Life Threatening (Major) Side Effects in Common
 
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Depression is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Inflammation of the Middle Tissue Heart Muscle - Myocarditis is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Hepatitis is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Fever is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Increased Eosinophils in the Blood - Eosinophilia is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of both Provigil and Nuvigil.
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of both Provigil and Nuvigil.

Provigil Has 25 Life Threatening (Major) Side Effects Not Found in Nuvigil
 
Critical Seriousness - Mental Disturbance - Psychiatric Disturbance is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Throat Irritation - Pharyngitis is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Bloody Urine - Hematuria is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Chills is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Cannot Empty Bladder - Urinary Retention is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Abnormal Peeling of Skin - Abnormal Desquamation is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Loss of Memory - Memory Impairment is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - High Blood Sugar - Hyperglycemia is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Problems with Eyesight - Visual Changes is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Painful, Red or Swollen Mouth - Stomatitis is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Mood Changes is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Asthma - Bronchial Asthma is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Lazy Eye - Amblyopia is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Visible Water Retention - Edema is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Chest Pain is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Hyperactive Behavior - Hyperkinesis is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Small Skin Blister - Blistering Skin is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Voluntary Movement Difficulty - Dyskinesia is a Life Threatening Side Effect of Provigil but not Nuvigil.

Nuvigil Has 4 Life Threatening (Major) Side Effects Not Found in Provigil
 
Critical Seriousness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Hallucination - Hallucinations is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Delusions - Delusional Disorder is a Life Threatening Side Effect of Provigil but not Nuvigil.
Critical Seriousness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Provigil but not Nuvigil.

Provigil and Nuvigil Have 4 Most Frequently Occurring Side Effects in Common
 
Dizzy - Dizziness is a Frequently Occurring Side Effect of both Provigil and Nuvigil.
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of both Provigil and Nuvigil.
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of both Provigil and Nuvigil.
Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of both Provigil and Nuvigil.

Provigil Has 6 Most Frequently Occurring Side Effects Not Found in Nuvigil
 
Backache - Back Pain is a Frequently Occurring Side Effect of Provigil but not Nuvigil.
Anxious - Anxiety is a Frequently Occurring Side Effect of Provigil but not Nuvigil.
Diarrhea is a Frequently Occurring Side Effect of Provigil but not Nuvigil.
Inflammation of the Nose - Rhinitis is a Frequently Occurring Side Effect of Provigil but not Nuvigil.
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Provigil but not Nuvigil.
Nervous - Nervousness is a Frequently Occurring Side Effect of Provigil but not Nuvigil.

Nuvigil Has 0 Most Frequently Occurring Side Effects Not Found in Nuvigil
 

Provigil and Nuvigil Treat 11 Conditions in Common
 
Sleepiness Due To Obstructive Sleep Apnea is treated by both Provigil and Nuvigil.
Sleepiness Due To Shift Work Sleep Disorder is treated by both Provigil and Nuvigil.
Recurring Sleep Episodes During the Day - Narcolepsy Syndrome is treated by both Provigil and Nuvigil.

Provigil has 14 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Provigil.

Provigil Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications 

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Provigil.

Depression is a contraindication of Provigil.

Left Ventricular Hypertrophy is a contraindication of Provigil.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Provigil.

Mitral Valve Prolapse - Mitral Valve Prolapse Syndrome is a contraindication of Provigil.

Myocardial Infarction - Heart Attack is a contraindication of Provigil.

Myocardial Ischemia - Disease of Inadequate Blood Flow to the Heart Muscle is a contraindication of Provigil.

Psychotic Disorder - Mental Disorder with Loss of Normal Personality & Reality is a contraindication of Provigil.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Provigil.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Provigil.

Unstable Angina Pectoris - Unpredictable Severe Constricting Chest Pain is a contraindication of Provigil.

Contraindication Warnings 

Aggressive Behavior is a contraindication of Provigil.

Hypertension - High Blood Pressure is a contraindication of Provigil.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Provigil.

Nuvigil has 8 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Nuvigil.

Nuvigil Oral Contraindications
(grouped by decreasing seriouosness level)

Relative Contraindications 

Depression is a contraindication of Nuvigil.

Left Ventricular Hypertrophy is a contraindication of Nuvigil.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Nuvigil.

Mitral Valve Prolapse - Mitral Valve Prolapse Syndrome is a contraindication of Nuvigil.

Psychotic Disorder - Mental Disorder with Loss of Normal Personality & Reality is a contraindication of Nuvigil.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Nuvigil.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Nuvigil.

Contraindication Warnings 

Hypertension - High Blood Pressure is a contraindication of Nuvigil.
Provigil - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose include fast/irregular heartbeat, restlessness, hallucinations.

Nuvigil - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose include: fast/irregular heartbeat, restlessness, hallucinations.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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