Compare Suboxone vs Naltrexone

Compare Suboxone

vs Naltrexone

Compare Suboxone to Naltrexone. To make a decision about Suboxone vs Naltrexone, click here for a Medication Risk Map to help you select Suboxone or Naltrexone

Click here for Drug Interactions and Side Effects of Suboxone.
Click here for Drug Interactions and Side Effects of Naltrexone.
Click here to see the effects of combining Suboxone and Naltrexone.

Uses of Suboxone

Suboxone is also known by the generic name Buprenorphine-Naloxone

USES:
This medication contains 2 medicines:
buprenorphine and naloxone. It is used to treat narcotic (opioid) dependence/addiction. Buprenorphine belongs to a class of drugs called mixed narcotic agonist-antagonists. Buprenorphine helps prevent withdrawal symptoms caused by stopping other opiate-type narcotics.

Naloxone is a narcotic antagonist that blocks the effect of narcotics and can cause severe narcotic withdrawal when injected. It has little effect when taken by mouth or dissolved under the tongue. It is combined with buprenorphine to prevent abuse and misuse (injection) of this medication. This combination medication is used as part of a complete treatment program for drug abuse (such as compliance monitoring, counseling, behavioral contract, lifestyle changes).

Uses of Naltrexone

USES:
This medication is used to prevent people who have been addicted to certain drugs (opiates) from taking them again. It is used as part of a complete treatment program for drug abuse (e.g., compliance monitoring, counseling, behavioral contract, lifestyle changes). This medication must not be used in people currently taking opiates, including methadone. Doing so can cause sudden withdrawal symptoms.

Naltrexone belongs to a class of drugs known as opiate antagonists. It works in the brain to prevent opiate effects (e.g., feelings of well-being, pain relief). It also decreases the desire to take opiates.

This medication is also used to treat alcohol abuse. It can help people drink less alcohol or stop drinking altogether. It also decreases the desire to drink alcohol when used with a treatment program that includes counseling, support, and lifestyle changes.

Suboxone and Naltrexone Have 2 Life Threatening (Major) Side Effects in Common

Critical Seriousness - Depression is a Life Threatening Side Effect of both Suboxone and Naltrexone. Critical Seriousness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of both Suboxone and Naltrexone. Click for a searchable interactive map of all Life Threatening Side Effects associated with Suboxone and Naltrexone.

Suboxone Has 8 Life Threatening (Major) Side Effects Not Found in Naltrexone

Critical Seriousness - Backache - Back Pain is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Pain is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Infection is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Significant Decrease in Lung Function - Respiratory Depression is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Hepatitis is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Abscess is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Suboxone and Naltrexone.

Naltrexone Has 24 Life Threatening (Major) Side Effects Not Found in Suboxone

Critical Seriousness - Earache is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Pain in the Eye - Ocular Pain is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Hallucination - Hallucinations is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Blurred Vision is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Inflammation of a Vein - Phlebitis is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Difficult or Painful Urination - Dysuria is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Ringing in the Ears - Tinnitus is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Fever is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Mood Changes is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Eye Irritation - Ocular Irritation is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Mental Impairment is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Inflammation of the Eye - Ocular Inflammation is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Stomach or Intestinal Ulcer - Gastrointestinal Ulcer is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Critical Seriousness - Frequent Urination - Increased Urinary Frequency is a Life Threatening Side Effect of Suboxone but not Naltrexone.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Suboxone and Naltrexone.

Suboxone and Naltrexone Have 5 Most Frequently Occurring Side Effects in Common

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of both Suboxone and Naltrexone.

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of both Suboxone and Naltrexone.

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of both Suboxone and Naltrexone.

Anxious - Anxiety is a Frequently Occurring Side Effect of both Suboxone and Naltrexone.

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of both Suboxone and Naltrexone.

Click for a searchable interactive map of all Side Effects associated with Suboxone and Naltrexone.

Suboxone Has 6 Most Frequently Occurring Side Effects Not Found in Naltrexone

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Suboxone but not Naltrexone.

Backache - Back Pain is a Frequently Occurring Side Effect of Suboxone but not Naltrexone.

Depression is a Frequently Occurring Side Effect of Suboxone but not Naltrexone.

Pain is a Frequently Occurring Side Effect of Suboxone but not Naltrexone.

Infection is a Frequently Occurring Side Effect of Suboxone but not Naltrexone.

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Suboxone but not Naltrexone.

Click for a searchable interactive map of all Side Effects associated with Suboxone and Naltrexone.

Naltrexone Has 8 Most Frequently Occurring Side Effects Not Found in Naltrexone

Muscle Pain - Myalgia is a Frequently Occurring Side Effect of Naltrexone but not Suboxone.

Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Frequently Occurring Side Effect of Naltrexone but not Suboxone.

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Naltrexone but not Suboxone.

Joint Pain - Arthralgia is a Frequently Occurring Side Effect of Naltrexone but not Suboxone.

Giant Hives - Angioedema is a Frequently Occurring Side Effect of Naltrexone but not Suboxone.

Reaction due to an Allergy - Allergic Reactions is a Frequently Occurring Side Effect of Naltrexone but not Suboxone.

Low Energy - Fatigue is a Frequently Occurring Side Effect of Naltrexone but not Suboxone.

Rash - Skin Rash is a Frequently Occurring Side Effect of Naltrexone but not Suboxone.

Click for a searchable interactive map of all Side Effects associated with Suboxone and Naltrexone.

Suboxone and Naltrexone Treat 1 Conditions in Common

Prevention of Opiate Drug Abuse - Prevention of Opioid Abuse is treated by both Suboxone and Naltrexone.

Suboxone has 31 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Suboxone.

Suboxone Sublingual Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications

Pain in Opioid Naive Patients is a contraindication of Suboxone.

Paralytic Ileus - Paralysis of the Intestines is a contraindication of Suboxone.

Relative Contraindications

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Suboxone.

Alcohol Intoxication is a contraindication of Suboxone.

CNS Depression - Abnormal Nervous System Function Affecting Mental Alertness is a contraindication of Suboxone.

Chronic Disease of Respiratory System - Chronic Lung or Breathing Passage Problem is a contraindication of Suboxone.

Chronic Hepatitis C is a contraindication of Suboxone.

Chronic Obstructive Pulmonary Disease - Chronic Obstructive Lung Disease is a contraindication of Suboxone.

Chronic Type B Viral Hepatitis - Chronic Hepatitis B is a contraindication of Suboxone.

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Suboxone.

Cor Pulmonale is a contraindication of Suboxone.

Head Injury is a contraindication of Suboxone.

Hypercapnia - Excess Amount of Carbon Dioxide in the Blood is a contraindication of Suboxone.

Hypoxia - Decreased Oxygen In The Tissues Or Blood is a contraindication of Suboxone.

Intracranial Hypertension - High Pressure Within the Skull is a contraindication of Suboxone.

Intracranial Lesion - Lesion of Brain is a contraindication of Suboxone.

Kyphoscoliosis with Respiratory Compromise - Curvature of the Spine with Respiratory Compromise is a contraindication of Suboxone.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Suboxone.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Suboxone.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Suboxone.

Respiratory Insufficiency - Lung Failure causing Loss of Breath is a contraindication of Suboxone.

Torsades de Pointes - Very Rapid Heartbeat - Torsades de Pointes is a contraindication of Suboxone.

Toxic Psychosis - Mental Disorder Resulting from Poisonous Agents is a contraindication of Suboxone.

Untreated Hypothyroidism - Untreated Decreased Level of Thyroid Hormones is a contraindication of Suboxone.

Contraindication Warnings

Adrenocortical Insufficiency - Decreased Function of the Adrenal Gland is a contraindication of Suboxone.

Alcohol Withdrawal Delirium - Psychosis caused by Sudden Alcohol Withdrawal is a contraindication of Suboxone.

Benign Prostatic Hypertrophy - Enlarged Prostate is a contraindication of Suboxone.

Biliary Tract Disorder - Biliary and Gallbladder Problem is a contraindication of Suboxone.

Debilitation - Weakened Patient is a contraindication of Suboxone.

Disease of Liver - Liver Problems is a contraindication of Suboxone.

Urethral Stricture - Narrowing of the Tube that Empties Urine From the Bladder is a contraindication of Suboxone.

Naltrexone has 11 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Naltrexone.

Naltrexone Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications

Acute Hepatic Failure - Acute Liver Failure is a contraindication of Naltrexone.

Acute Hepatitis - Active Inflammation of the Liver is a contraindication of Naltrexone.

Opioid Dependence - Narcotic Addiction is a contraindication of Naltrexone.

Opioid Use Within Last 4 Hours in Narcotic-Dependent Patient - Opioid Use Within Last 4 Hours in Narcotic Addicted Patient is a contraindication of Naltrexone.

Opioid Withdrawal Symptoms - Symptoms associated with Morphine or Codeine Withdrawal is a contraindication of Naltrexone.

Relative Contraindications

Depression is a contraindication of Naltrexone.

Disease of Liver - Liver Problems is a contraindication of Naltrexone.

Eosinophilic Pneumonia - Pneumonia with High Amount of Eosinophil White Blood Cells is a contraindication of Naltrexone.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Naltrexone.

Contraindication Warnings

Increased Creatine Phosphokinase - Increase in the Product of Metabolism Found in Muscle is a contraindication of Naltrexone.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Naltrexone.

Suboxone - Symptoms of overdose may include
slow breathing, slow heartbeat, loss of consciousness.

Naltrexone - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.