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Heavy hITters
 

Uses of Truvada
 
Truvada is also known by the generic name Emtricitabine-Tenofovir


USES:
This product is a combination of two different drugs, emtricitabine and tenofovir. This product is used to treat HIV infection. It works by slowing the growth of the virus. Emtricitabine is called a nucleoside reverse transcriptase inhibitor, while tenofovir is called a nucleotide reverse transcriptase inhibitor. They are often referred to as NRTIs.

NRTIs are usually used in combination with other HIV medications (e.g., protease inhibitor). Consult your doctor or pharmacist for more details.

This product and other anti-HIV drugs may help to control your HIV infection, thereby improving your quality of life and lowering your risk of getting complications from HIV (e.g., opportunistic infections, cancer).

This product is not a cure for HIV infection, and it does not prevent the spread of HIV to others through sexual contact or blood contamination (e.g., sharing used needles).


Uses of Combivir
 
Combivir is also known by the generic name Lamivudine-Zidovudine


USES:
This product contains 2 drugs:
lamivudine and zidovudine. It is used with other medications to help control your HIV infection, thereby improving your quality of life. It helps to decrease the amount of HIV in your body so your immune system can work better. This product also lowers your risk of getting HIV disease complications (such as new infections, cancer). Both lamivudine and zidovudine belong to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).

Lamivudine/zidovudine is not a cure for HIV infection and it does not prevent the spread of HIV to others through sexual contact or blood contamination (such as sharing used needles).


Truvada and Combivir Have 8 Life Threatening (Major) Side Effects in Common
 
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of both Truvada and Combivir.
Critical Seriousness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of both Truvada and Combivir.
Critical Seriousness - Increased Blood Acidity due to High Levels of Lactic Acid - Lactic Acidosis is a Life Threatening Side Effect of both Truvada and Combivir.
Critical Seriousness - Disease of the Nerves - Neuropathy is a Life Threatening Side Effect of both Truvada and Combivir.
Critical Seriousness - Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Life Threatening Side Effect of both Truvada and Combivir.
Critical Seriousness - Enlarged Fatty Liver - Steatosis of Liver is a Life Threatening Side Effect of both Truvada and Combivir.
Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of both Truvada and Combivir.
Critical Seriousness - Serious Muscle Damage that may Lead to Kidney Failure - Rhabdomyolysis is a Life Threatening Side Effect of both Truvada and Combivir.

Truvada Has 12 Life Threatening (Major) Side Effects Not Found in Combivir
 
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Pneumonia is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Softening of Bones - Osteomalacia is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Low Amount of Potassium in the Blood - Hypokalemia is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Fanconi's Syndrome - Fanconi Syndrome is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Low Amount of Phosphate in the Blood - Hypophosphatemia is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Acute Kidney Disease - Acute Renal Disease is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Kidney Failure - Renal Failure is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Chest Pain is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Kidney Disease - Renal Disease is a Life Threatening Side Effect of Truvada but not Combivir.

Combivir Has 18 Life Threatening (Major) Side Effects Not Found in Truvada
 
Critical Seriousness - Anemia is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Muscle Disease - Myopathy is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Erythema Multiforme is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Disease of the Muscle of the Heart with Enlargement - Cardiomyopathy is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - High Blood Sugar - Hyperglycemia is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Painful, Red or Swollen Mouth - Stomatitis is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Enlarged Spleen - Hypersplenism is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Vasculitis is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Truvada but not Combivir.
Critical Seriousness - Wheezing is a Life Threatening Side Effect of Truvada but not Combivir.

Truvada and Combivir Have 1 Most Frequently Occurring Side Effects in Common
 
Abnormal Fat Distribution associated with HIV - Lipodystrophy associated with Human Immunodeficiency Virus Infection is a Frequently Occurring Side Effect of both Truvada and Combivir.

Truvada Has 1 Most Frequently Occurring Side Effects Not Found in Combivir
 
Chest Pain is a Frequently Occurring Side Effect of Truvada but not Combivir.

Combivir Has 6 Most Frequently Occurring Side Effects Not Found in Combivir
 
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Combivir but not Truvada.
Decreased White Blood Cells - Leukopenia is a Frequently Occurring Side Effect of Combivir but not Truvada.
Acute Inflammation of the Pancreas - Acute Pancreatitis is a Frequently Occurring Side Effect of Combivir but not Truvada.
Numbness and Tingling - Paresthesia is a Frequently Occurring Side Effect of Combivir but not Truvada.
Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Frequently Occurring Side Effect of Combivir but not Truvada.
Diarrhea is a Frequently Occurring Side Effect of Combivir but not Truvada.

Truvada and Combivir Treat 5 Conditions in Common
 
Prevention of HIV Infection after Exposure is treated by both Truvada and Combivir.
HIV - HIV Infection is treated by both Truvada and Combivir.

Truvada has 16 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Truvada.

Truvada Oral Contraindications
(grouped by decreasing seriousness level)

Absolute Contraindications 

Acute Renal Disease - Acute Kidney Disease is a contraindication of Truvada.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Truvada.

Lactic Acidosis - Increased Blood Acidity due to High Levels of Lactic Acid is a contraindication of Truvada.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Truvada.

Steatosis of Liver - Enlarged Fatty Liver is a contraindication of Truvada.

Relative Contraindications 

Disease of Liver - Liver Problems is a contraindication of Truvada.

Fanconi Syndrome - Fanconi's Syndrome is a contraindication of Truvada.

Hypophosphatemia - Low Amount of Phosphate in the Blood is a contraindication of Truvada.

Obesity - Overweight is a contraindication of Truvada.

Osteomalacia - Softening of Bones is a contraindication of Truvada.

Pathological Fracture - Broken Bone due to Disease or Illness is a contraindication of Truvada.

Renal Disease - Kidney Disease is a contraindication of Truvada.

Contraindication Warnings 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Truvada.

Chronic Type B Viral Hepatitis - Chronic Hepatitis B is a contraindication of Truvada.

Osteopenia - Decreased Calcification or Density of Bone is a contraindication of Truvada.

Renal Disease - Kidney Disease is a contraindication of Truvada.

Combivir has 18 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Combivir.

Combivir Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Combivir.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Combivir.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Combivir.

Lactic Acidosis - Increased Blood Acidity due to High Levels of Lactic Acid is a contraindication of Combivir.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Combivir.

Steatosis of Liver - Enlarged Fatty Liver is a contraindication of Combivir.

Relative Contraindications 

Anemia is a contraindication of Combivir.

Bone Marrow Depression - Decreased Function of Bone Marrow is a contraindication of Combivir.

Hepatomegaly - Enlarged Liver is a contraindication of Combivir.

Myopathy - Muscle Disease is a contraindication of Combivir.

Myositis - Muscle Inflammation is a contraindication of Combivir.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Combivir.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Combivir.

Contraindication Warnings 

Disease of Liver - Liver Problems is a contraindication of Combivir.

Drug Resistance to Anti-retroviral Therapy is a contraindication of Combivir.

Obesity - Overweight is a contraindication of Combivir.

Renal Disease - Kidney Disease is a contraindication of Combivir.

Toxic Amblyopia - Vision Changes caused by Medications is a contraindication of Combivir.
Truvada - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Combivir - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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