Compare Tussionex vs Promethazine

Compare Tussionex

vs Promethazine

Compare Tussionex to Promethazine. To make a decision about Tussionex vs Promethazine, click here for a Medication Risk Map to help you select Tussionex or Promethazine

Click here for Drug Interactions and Side Effects of Tussionex.
Click here for Drug Interactions and Side Effects of Promethazine.
Click here to see the effects of combining Tussionex and Promethazine.

Uses of Tussionex

Tussionex is also known by the generic name Chlorpheniramine-Hydrocodone

USES:
This combination product is used to treat coughs and other symptoms caused by the common cold or allergies. This product contains 2 medications:
hydrocodone and chlorpheniramine. Hydrocodone is a narcotic cough suppressant (antitussive) that acts on a certain part of the brain (cough center) to reduce the urge to cough. Chlorpheniramine is an antihistamine that helps to relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, this product is not recommended to treat cold symptoms in children younger than 6 years. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Giving more than the recommended dose or using this medication along with other cough-and-cold products has resulted in serious (even fatal) side effects, including slowed/stopped breathing. Talk to the doctor or pharmacist before giving other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). Do not use this product to make a child sleepy.

Uses of Promethazine

USES:
Promethazine is used to prevent and treat nausea and vomiting related to certain conditions (e.g., motion sickness, before/after surgery). It is also used to treat allergic symptoms such as rash, itching, and runny nose. It may be used for a short time to treat a runny nose due to the common cold. It may also be used to help you feel calmer before/after surgery or to help certain narcotic pain relievers (e.g., meperidine) work better.

Promethazine is an antihistamine. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its other effects (e.g., anti-nausea, calming, pain relief) may work by affecting other natural substances (e.g., acetylcholine) and by acting directly on certain parts of the brain.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

Tussionex and Promethazine Have 6 Life Threatening (Major) Side Effects in Common

Critical Seriousness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of both Tussionex and Promethazine.

Critical Seriousness - Hallucination - Hallucinations is a Life Threatening Side Effect of both Tussionex and Promethazine.

Critical Seriousness - Significant Decrease in Lung Function - Respiratory Depression is a Life Threatening Side Effect of both Tussionex and Promethazine.

Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of both Tussionex and Promethazine.

Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of both Tussionex and Promethazine.

Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of both Tussionex and Promethazine.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Tussionex and Promethazine.

Tussionex Has 20 Life Threatening (Major) Side Effects Not Found in Promethazine

Critical Seriousness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Depression is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Extra Heartbeat - Extrasystoles is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Involuntary Muscle Movements - Involuntary Muscle Movement is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Ringing in the Ears - Tinnitus is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - A Spasm of the Larynx - Laryngismus is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Fit - Tonic Clonic Seizure is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Increased Spinal Fluid Pressure - Increased Cerebrospinal Fluid Pressure is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Collapsed Portion of Lung - Atelectasis is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Change in Pulse - Pulse Changes is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Blood Disorder - Blood Dyscrasias is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Muscle Stiffness - Muscle Rigidity is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Tussionex but not Promethazine.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Tussionex and Promethazine.

Promethazine Has 12 Life Threatening (Major) Side Effects Not Found in Tussionex

Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Delirium is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Thrombotic Thrombocytopenic Purpura is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Lower Seizure Threshold is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Asthma - Bronchial Asthma is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Tussionex but not Promethazine.

Critical Seriousness - Periods of Not Breathing - Apnea is a Life Threatening Side Effect of Tussionex but not Promethazine.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Tussionex and Promethazine.

Tussionex and Promethazine Have 4 Most Frequently Occurring Side Effects in Common

Dizzy - Dizziness is a Frequently Occurring Side Effect of both Tussionex and Promethazine.

An Increase in the Thickness of Lung Secretions - Thick Bronchial Secretions is a Frequently Occurring Side Effect of both Tussionex and Promethazine.

Drowsiness - Drowsy is a Frequently Occurring Side Effect of both Tussionex and Promethazine.

Abnormally Low Blood Pressure - Hypotension is a Frequently Occurring Side Effect of both Tussionex and Promethazine.

Click for a searchable interactive map of all Side Effects associated with Tussionex and Promethazine.

Tussionex Has 3 Most Frequently Occurring Side Effects Not Found in Promethazine

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Tussionex but not Promethazine.

Feeling Faint - Fainting is a Frequently Occurring Side Effect of Tussionex but not Promethazine.

Not Feeling Well - Malaise is a Frequently Occurring Side Effect of Tussionex but not Promethazine.

Click for a searchable interactive map of all Side Effects associated with Tussionex and Promethazine.

Promethazine Has 12 Most Frequently Occurring Side Effects Not Found in Promethazine

Confused - Impaired Cognition is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Blurred Vision is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Easily Angered or Annoyed - Irritability is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Over Excitement - Excitement is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Nightmares is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Problems with Eyesight - Visual Changes is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Sun-Sensitive Skin - Skin Photosensitivity is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Fast Heartbeat - Tachyarrhythmia is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Nervous - Nervousness is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Rash - Skin Rash is a Frequently Occurring Side Effect of Promethazine but not Tussionex.

Click for a searchable interactive map of all Side Effects associated with Tussionex and Promethazine.

Tussionex and Promethazine Treat 0 Conditions in Common

Tussionex has 50 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Tussionex.

Tussionex Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Acutely Deteriorating Asthma - Asthma That Is Getting Worse is a contraindication of Tussionex.

Alcohol Intoxication is a contraindication of Tussionex.

Alcohol Withdrawal Delirium - Psychosis caused by Sudden Alcohol Withdrawal is a contraindication of Tussionex.

Benign Prostatic Hypertrophy - Enlarged Prostate is a contraindication of Tussionex.

Bladder Outflow Obstruction - Blockage of Urinary Bladder is a contraindication of Tussionex.

Bradycardia - Slow Heartbeat is a contraindication of Tussionex.

Brain Neoplasm - Brain Tumor is a contraindication of Tussionex.

CNS Depression - Abnormal Nervous System Function Affecting Mental Alertness is a contraindication of Tussionex.

Chronic Idiopathic Constipation - Chronic Difficulty having a Bowel Movement is a contraindication of Tussionex.

Coma is a contraindication of Tussionex.

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Tussionex.

Cor Pulmonale is a contraindication of Tussionex.

Debilitation - Weakened Patient is a contraindication of Tussionex.

Dehydration - Extreme Loss of Body Water is a contraindication of Tussionex.

Gastrointestinal Obstruction - Stomach or Intestine Blockage is a contraindication of Tussionex.

Gastrointestinal Tract Surgery - Stomach or Intestinal Tract Operation is a contraindication of Tussionex.

Head Injury is a contraindication of Tussionex.

Hypercapnia - Excess Amount of Carbon Dioxide in the Blood is a contraindication of Tussionex.

Hypotension - Abnormally Low Blood Pressure is a contraindication of Tussionex.

Hypoxia - Decreased Oxygen In The Tissues Or Blood is a contraindication of Tussionex.

Inflammatory Bowel Disease is a contraindication of Tussionex.

Intracranial Hypertension - High Pressure Within the Skull is a contraindication of Tussionex.

Intracranial Lesion - Lesion of Brain is a contraindication of Tussionex.

Morbid Obesity is a contraindication of Tussionex.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Tussionex.

Primary Adrenocortical Insufficiency - Addison's Disease is a contraindication of Tussionex.

Pulmonary Emphysema - Emphysema is a contraindication of Tussionex.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Tussionex.

Seizure Disorder - Seizures is a contraindication of Tussionex.

Shock is a contraindication of Tussionex.

Stenosing Peptic Ulcer is a contraindication of Tussionex.

Substance Abuse - Misuse or Excessive Use of Drugs is a contraindication of Tussionex.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Tussionex.

Toxic Psychosis - Mental Disorder Resulting from Poisonous Agents is a contraindication of Tussionex.

Ulcerative Colitis - Ulcerated Colon is a contraindication of Tussionex.

Untreated Hypothyroidism - Untreated Decreased Level of Thyroid Hormones is a contraindication of Tussionex.

Urethral Stricture - Narrowing of the Tube that Empties Urine From the Bladder is a contraindication of Tussionex.

Urinary Retention - Cannot Empty Bladder is a contraindication of Tussionex.

Contraindication Warnings

Acute Abdominal Pain - Intense Abdominal Pain is a contraindication of Tussionex.

Biliary Spasm - Spasm of a Bile Duct Tract is a contraindication of Tussionex.

Chronic Obstructive Pulmonary Disease - Chronic Obstructive Lung Disease is a contraindication of Tussionex.

Constipation - Incomplete or Infrequent Bowel Movements is a contraindication of Tussionex.

Disease of Liver - Liver Problems is a contraindication of Tussionex.

Drug Dependence - Taking Habit Forming Drugs is a contraindication of Tussionex.

Gallbladder Disease - Disease of the Gallbladder is a contraindication of Tussionex.

Hypertension - High Blood Pressure is a contraindication of Tussionex.

Hyperthyroidism - Overactive Thyroid Gland is a contraindication of Tussionex.

Hypothyroidism - Underactive Thyroid is a contraindication of Tussionex.

Mood Changes is a contraindication of Tussionex.

Renal Disease - Kidney Disease is a contraindication of Tussionex.

Promethazine has 22 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Promethazine.

Promethazine Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications

Coma is a contraindication of Promethazine.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Promethazine.

Neuroleptic Malignant Syndrome is a contraindication of Promethazine.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Promethazine.

Relative Contraindications

Benign Prostatic Hypertrophy - Enlarged Prostate is a contraindication of Promethazine.

Bladder Outflow Obstruction - Blockage of Urinary Bladder is a contraindication of Promethazine.

CNS Depression - Abnormal Nervous System Function Affecting Mental Alertness is a contraindication of Promethazine.

Chronic Idiopathic Constipation - Chronic Difficulty having a Bowel Movement is a contraindication of Promethazine.

Chronic Obstructive Pulmonary Disease - Chronic Obstructive Lung Disease is a contraindication of Promethazine.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Promethazine.

Pyloroduodenal Obstruction - Narrowing of Opening Between Stomach and Small Intestine is a contraindication of Promethazine.

Sleep Apnea - Temporarily Stops Breathing While Sleeping is a contraindication of Promethazine.

Stenosing Peptic Ulcer is a contraindication of Promethazine.

Contraindication Warnings

Bone Marrow Depression - Decreased Function of Bone Marrow is a contraindication of Promethazine.

CNS Disorder - Diseases of the Brain and Spinal Cord is a contraindication of Promethazine.

Disease of Cardiovascular System - Disease of the Heart and Blood Vessels is a contraindication of Promethazine.

Disease of Liver - Liver Problems is a contraindication of Promethazine.

Encephalopathy - Any Disorder of the Brain is a contraindication of Promethazine.

Epilepsy - Epileptic Seizure is a contraindication of Promethazine.

Gastrointestinal Obstruction - Stomach or Intestine Blockage is a contraindication of Promethazine.

Hyperbilirubinemia - High Amount of Bilirubin in the Blood is a contraindication of Promethazine.

Lower Seizure Threshold is a contraindication of Promethazine.

Tussionex - Symptoms of overdose may include
slow/shallow breathing, severe drowsiness/dizziness, mental/mood changes (such as confusion, agitation), cold/clammy skin, fast/slow/irregular heartbeat, seizures.

Promethazine - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe dizziness, fainting, very slow/shallow breathing, loss of consciousness, muscle stiffness/twitching, hot dry skin, widened pupils.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.