Compare Zofran vs Compazine

Compare Zofran

vs Compazine

Compare Zofran to Compazine. To make a decision about Zofran vs Compazine, click here for a Medication Risk Map to help you select Zofran or Compazine

Click here for Drug Interactions and Side Effects of Zofran.
Click here for Drug Interactions and Side Effects of Compazine.
Click here to see the effects of combining Zofran and Compazine.

Uses of Zofran

Zofran is also known by the generic name Ondansetron Hcl USES: This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.

Uses of Compazine

Compazine is also known by the generic name Prochlorperazine Edisylate

Compazine is also known by the generic name Prochlorperazine Maleate

Compazine is also known by the generic name Prochlorperazine

USES:
This medication is used to treat severe nausea and vomiting from various causes (e.g., anti-cancer treatment, migraine headaches, after surgery).

Prochlorperazine is a phenothiazine medication that works by affecting the balance of natural chemicals (neurotransmitters) in the brain to reduce nausea and the urge to vomit.

This medication is not recommended for use in children under 2 years old or during surgery on children.

Zofran and Compazine Have 4 Life Threatening (Major) Side Effects in Common

Critical Seriousness - Blurred Vision is a Life Threatening Side Effect of both Zofran and Compazine.

Critical Seriousness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of both Zofran and Compazine.

Critical Seriousness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of both Zofran and Compazine.

Critical Seriousness - Feeling Faint - Fainting is a Life Threatening Side Effect of both Zofran and Compazine.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zofran and Compazine.

Zofran Has 12 Life Threatening (Major) Side Effects Not Found in Compazine

Critical Seriousness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Shock is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Decreased Oxygen In The Tissues Or Blood - Hypoxia is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Temporary Blindness - Transient Blindness is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Zofran but not Compazine.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zofran and Compazine.

Compazine Has 19 Life Threatening (Major) Side Effects Not Found in Zofran

Critical Seriousness - Continued Painful Erection - Priapism is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Contact Dermatitis is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Pigmentary Retinopathy is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Dark Pigmentation of Tissues or Organs - Melanosis is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Sunstroke - Heat Stroke is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Difficult or Painful Urination - Dysuria is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Problems with Eyesight - Visual Changes is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Very Rapid Heartbeat - Torsades de Pointes - Torsades de Pointes is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Abnormal Movements of Face Muscles and Tongue - Tardive Dyskinesia is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Sun-Sensitive Skin - Skin Photosensitivity is a Life Threatening Side Effect of Zofran but not Compazine.

Critical Seriousness - Low Body Temperature - Hypothermia is a Life Threatening Side Effect of Zofran but not Compazine.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zofran and Compazine.

Zofran and Compazine Have 1 Most Frequently Occurring Side Effects in Common

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of both Zofran and Compazine. Click for a searchable interactive map of all Side Effects associated with Zofran and Compazine.

Zofran Has 4 Most Frequently Occurring Side Effects Not Found in Compazine

Chills is a Frequently Occurring Side Effect of Zofran but not Compazine.

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zofran but not Compazine.

Fever is a Frequently Occurring Side Effect of Zofran but not Compazine.

Diarrhea is a Frequently Occurring Side Effect of Zofran but not Compazine.

Click for a searchable interactive map of all Side Effects associated with Zofran and Compazine.

Compazine Has 14 Most Frequently Occurring Side Effects Not Found in Compazine

Dizzy - Dizziness is a Frequently Occurring Side Effect of Compazine but not Zofran.

Blurred Vision is a Frequently Occurring Side Effect of Compazine but not Zofran.

Decreased Sweating is a Frequently Occurring Side Effect of Compazine but not Zofran.

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Compazine but not Zofran.

Pigmentary Retinopathy is a Frequently Occurring Side Effect of Compazine but not Zofran.

Abnormally Low Blood Pressure - Hypotension is a Frequently Occurring Side Effect of Compazine but not Zofran.

Extrapyramidal Reaction - Extrapyramidal Disease is a Frequently Occurring Side Effect of Compazine but not Zofran.

Blood Pressure Drop Upon Standing - Orthostatic Hypotension is a Frequently Occurring Side Effect of Compazine but not Zofran.

Feeling Faint - Fainting is a Frequently Occurring Side Effect of Compazine but not Zofran.

A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Frequently Occurring Side Effect of Compazine but not Zofran.

Stuffy Nose - Nasal Congestion is a Frequently Occurring Side Effect of Compazine but not Zofran.

Increased Production of Saliva - Sialorrhea is a Frequently Occurring Side Effect of Compazine but not Zofran.

Abnormal Movements of Face Muscles and Tongue - Tardive Dyskinesia is a Frequently Occurring Side Effect of Compazine but not Zofran.

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Compazine but not Zofran.

Click for a searchable interactive map of all Side Effects associated with Zofran and Compazine.

Zofran and Compazine Treat 2 Conditions in Common

Prevent Nausea and Vomiting from Cancer Chemotherapy - Prevention of Cancer Chemotherapy-Induced Nausea and Vomiting is treated by both Zofran and Compazine. Nausea and Vomiting caused by Cancer Drugs - Cancer Chemotherapy-Induced Nausea and Vomiting is treated by both Zofran and Compazine.

Zofran has 2 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zofran.

Zofran Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Zofran.

Contraindication Warnings

Extrapyramidal Disease - Extrapyramidal Reaction is a contraindication of Zofran.

Compazine has 39 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Compazine.

Compazine Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications

Coma is a contraindication of Compazine.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Compazine.

Neuroleptic Malignant Syndrome is a contraindication of Compazine.

Severe Cardiovascular Disease - Serious Problems with Heart and Blood Vessels is a contraindication of Compazine.

Stupor is a contraindication of Compazine.

Relative Contraindications

Breast Carcinoma - Breast Cancer is a contraindication of Compazine.

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Compazine.

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Compazine.

Disease of Liver - Liver Problems is a contraindication of Compazine.

Extrapyramidal Disease - Extrapyramidal Reaction is a contraindication of Compazine.

Glaucoma - Increased Pressure in Eyes is a contraindication of Compazine.

Metabolic Syndrome X is a contraindication of Compazine.

Myocardial Infarction - Heart Attack is a contraindication of Compazine.

Myocardial Ischemia - Disease of Inadequate Blood Flow to the Heart Muscle is a contraindication of Compazine.

Obesity - Overweight is a contraindication of Compazine.

Organophosphate Insecticide Poisoning - Insecticide Poisoning due to Organophosphate Ingredient is a contraindication of Compazine.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Compazine.

Senile Dementia - Dementia in an Elderly Person is a contraindication of Compazine.

Symptomatic Prostatic Hypertrophy - Enlarged Prostate with Urination Problems is a contraindication of Compazine.

Tardive Dyskinesia - Abnormal Movements of Face Muscles and Tongue is a contraindication of Compazine.

Torsades de Pointes - Very Rapid Heartbeat - Torsades de Pointes is a contraindication of Compazine.

Urinary Retention - Cannot Empty Bladder is a contraindication of Compazine.

Contraindication Warnings

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Compazine.

Anemia is a contraindication of Compazine.

Angina is a contraindication of Compazine.

Bradycardia - Slow Heartbeat is a contraindication of Compazine.

Chronic Disease of Respiratory System - Chronic Lung or Breathing Passage Problem is a contraindication of Compazine.

Chronic Heart Failure is a contraindication of Compazine.

Epilepsy - Epileptic Seizure is a contraindication of Compazine.

Hyperglycemia - High Blood Sugar is a contraindication of Compazine.

Hyperprolactinemia - Increased Levels of Prolactin in the Blood is a contraindication of Compazine.

Leukopenia - Decreased White Blood Cells is a contraindication of Compazine.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Compazine.

Orthostatic Hypotension - Blood Pressure Drop Upon Standing is a contraindication of Compazine.

Parkinsonism - Parkinson Symptoms is a contraindication of Compazine.

Predisposition to Aspiration - Susceptible to Breathing Fluid Into Lungs is a contraindication of Compazine.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Compazine.

Visual Changes - Problems with Eyesight is a contraindication of Compazine.

Weight Gain is a contraindication of Compazine.

Zofran - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Compazine - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include restlessness, muscle spasms, deep sleep/loss of consciousness, seizures, irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.