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Uses of Zofran
 
Zofran is also known by the generic name Ondansetron Hcl


USES:
This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.


Uses of Emend
 
Emend is also known by the generic name Aprepitant


USES:
Aprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). This medication is also used to prevent nausea and vomiting after surgery. Aprepitant works by blocking one of the body's natural substances (substance P/neurokinin 1) that causes vomiting.

This medication will not treat nausea or vomiting if you already have it. Contact your doctor for further instructions if you are experiencing nausea or vomiting.


Zofran and Emend Have 5 Life Threatening (Major) Side Effects in Common
 
Critical Seriousness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of both Zofran and Emend.
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of both Zofran and Emend.
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of both Zofran and Emend.
Critical Seriousness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of both Zofran and Emend.
Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of both Zofran and Emend.
Click for a searchable interactive map of all Life Threatening Side Effects associated with Zofran and Emend.

Zofran Has 11 Life Threatening (Major) Side Effects Not Found in Emend
 
Critical Seriousness - Vocal Cord Swelling - Laryngeal Edema is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Blurred Vision is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Shock is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Decreased Oxygen In The Tissues Or Blood - Hypoxia is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Temporary Blindness - Transient Blindness is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Feeling Faint - Fainting is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Bronchospasm - Bronchospastic Pulmonary Disease is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Zofran but not Emend.
Click for a searchable interactive map of all Life Threatening Side Effects associated with Zofran and Emend.

Emend Has 31 Life Threatening (Major) Side Effects Not Found in Zofran
 
Critical Seriousness - Bacterial Infection of Blood or Tissues affecting the Whole Body - Bacterial Septicemia is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Anemia is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Blood Clot in a Deep Vein - Deep Venous Thrombosis is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Throat Irritation - Pharyngitis is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Muscle Weakness is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Severely Difficult Bowel Movements - Severe Constipation is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Depression is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Heart Attack - Myocardial Infarction is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Interstitial Pneumonitis is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Difficulty Swallowing - Dysphagia is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Diabetes - Diabetes Mellitus is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Extreme Loss of Body Water - Dehydration is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Low Amount of Potassium in the Blood - Hypokalemia is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Significant Decrease in Lung Function - Respiratory Depression is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Anxious - Anxiety is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Fever is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Malignant Tumor or Cancer - Malignancy is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Blood Clot in Lung - Pulmonary Thromboembolism is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Burning Stomach - Gastritis is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Excessive Sweating - Hyperhidrosis is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Visible Water Retention - Edema is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Kidney Disease - Renal Disease is a Life Threatening Side Effect of Zofran but not Emend.
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Zofran but not Emend.
Click for a searchable interactive map of all Life Threatening Side Effects associated with Zofran and Emend.

Zofran and Emend Have 2 Most Frequently Occurring Side Effects in Common
 
Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of both Zofran and Emend.
Diarrhea is a Frequently Occurring Side Effect of both Zofran and Emend.
Click for a searchable interactive map of all Side Effects associated with Zofran and Emend.

Zofran Has 3 Most Frequently Occurring Side Effects Not Found in Emend
 
Chills is a Frequently Occurring Side Effect of Zofran but not Emend.
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zofran but not Emend.
Fever is a Frequently Occurring Side Effect of Zofran but not Emend.
Click for a searchable interactive map of all Side Effects associated with Zofran and Emend.

Emend Has 8 Most Frequently Occurring Side Effects Not Found in Emend
 
Dizzy - Dizziness is a Frequently Occurring Side Effect of Emend but not Zofran.
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Emend but not Zofran.
Severely Difficult Bowel Movements - Severe Constipation is a Frequently Occurring Side Effect of Emend but not Zofran.
Extreme Loss of Body Water - Dehydration is a Frequently Occurring Side Effect of Emend but not Zofran.
Hiccups is a Frequently Occurring Side Effect of Emend but not Zofran.
Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Emend but not Zofran.
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Emend but not Zofran.
Low Energy - Fatigue is a Frequently Occurring Side Effect of Emend but not Zofran.
Click for a searchable interactive map of all Side Effects associated with Zofran and Emend.

Zofran and Emend Treat 3 Conditions in Common
 
Prevent Nausea and Vomiting from Cancer Chemotherapy - Prevention of Cancer Chemotherapy-Induced Nausea and Vomiting is treated by both Zofran and Emend.
Prevent Nausea and Vomiting After Surgery - Prevention of Post-Operative Nausea and Vomiting is treated by both Zofran and Emend.

Zofran has 2 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Zofran.

Zofran Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications 

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Zofran.

Contraindication Warnings 

Extrapyramidal Disease - Extrapyramidal Reaction is a contraindication of Zofran.

Emend has 1 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Emend.

Emend Oral Contraindications
(grouped by decreasing seriouosness level)

Contraindication Warnings 

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Emend.
Zofran - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Emend - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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