Compare Zoloft vs Lexapro

Compare Zoloft

vs Lexapro

Compare Zoloft to Lexapro. To make a decision about Zoloft vs Lexapro, click here for a Medication Risk Map to help you select Zoloft or Lexapro

Click here for Drug Interactions and Side Effects of Zoloft.
Click here for Drug Interactions and Side Effects of Lexapro.
Click here to see the effects of combining Zoloft and Lexapro.

Uses of Zoloft

Zoloft is also known by the generic name Sertraline

USES:
Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

Uses of Lexapro

Lexapro is also known by the generic name Escitalopram USES: Escitalopram is an antidepressant (selective serotonin reuptake inhibitor-SSRI) used to treat depression and anxiety. It works by restoring the balance of certain natural substances (neurotransmitters such as serotonin) in the brain. Escitalopram may improve your feelings of well-being and energy level and decrease nervousness.

Zoloft and Lexapro Have 8 Life Threatening (Major) Side Effects in Common

Critical Seriousness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of both Zoloft and Lexapro.

Critical Seriousness - Hemorrhage is a Life Threatening Side Effect of both Zoloft and Lexapro.

Critical Seriousness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of both Zoloft and Lexapro.

Critical Seriousness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of both Zoloft and Lexapro.

Critical Seriousness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of both Zoloft and Lexapro.

Critical Seriousness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of both Zoloft and Lexapro.

Critical Seriousness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of both Zoloft and Lexapro.

Critical Seriousness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of both Zoloft and Lexapro.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Lexapro.

Zoloft Has 17 Life Threatening (Major) Side Effects Not Found in Lexapro

Critical Seriousness - Sexual Problems - Abnormal Sexual Function is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Heart Throbbing or Pounding - Palpitations is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Mild Degree of Mania - Hypomania is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Fever is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Discharge of Milk in Men or Women when Not Breastfeeding - Galactorrhea not associated with Childbirth is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Altered Interest in Having Sexual Intercourse - Libido Changes is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Inability to have an Erection - Erectile Dysfunction is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Breast Tenderness - Mastalgia is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Zoloft but not Lexapro.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Lexapro.

Lexapro Has 25 Life Threatening (Major) Side Effects Not Found in Zoloft

Critical Seriousness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Blood Clot in a Deep Vein - Deep Venous Thrombosis is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Hallucination - Hallucinations is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Heart Attack - Myocardial Infarction is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Syndrome of Inappropriate Antidiuretic Hormone Secretion - SIADH Syndrome is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Mental Disorder with Loss of Normal Personality & Reality - Psychotic Disorder is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Very Rapid Heartbeat - Torsades de Pointes - Torsades de Pointes is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Hepatitis is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Involuntary Quivering - Tremors is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Atrial Fibrillation is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Aggressive Behavior is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Blood Clot in Lung - Pulmonary Thromboembolism is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Kidney Failure - Renal Failure is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Inflammation of the Lining of the Stomach and Intestines - Gastroenteritis is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Rapid Ventricular Heartbeat - Ventricular Tachycardia is a Life Threatening Side Effect of Zoloft but not Lexapro.

Critical Seriousness - Serious Muscle Damage that may Lead to Kidney Failure - Rhabdomyolysis is a Life Threatening Side Effect of Zoloft but not Lexapro.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Lexapro.

Zoloft and Lexapro Have 7 Most Frequently Occurring Side Effects in Common

Dizzy - Dizziness is a Frequently Occurring Side Effect of both Zoloft and Lexapro.

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of both Zoloft and Lexapro.

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of both Zoloft and Lexapro.

Diarrhea is a Frequently Occurring Side Effect of both Zoloft and Lexapro.

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of both Zoloft and Lexapro.

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of both Zoloft and Lexapro.

Low Energy - Fatigue is a Frequently Occurring Side Effect of both Zoloft and Lexapro.

Click for a searchable interactive map of all Side Effects associated with Zoloft and Lexapro.

Zoloft Has 11 Most Frequently Occurring Side Effects Not Found in Lexapro

Sexual Problems - Abnormal Sexual Function is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Drowsiness - Drowsy is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Gas - Flatulence is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Altered Interest in Having Sexual Intercourse - Libido Changes is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Inability to have an Erection - Erectile Dysfunction is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Weight Loss is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Zoloft but not Lexapro.

Click for a searchable interactive map of all Side Effects associated with Zoloft and Lexapro.

Lexapro Has 3 Most Frequently Occurring Side Effects Not Found in Lexapro

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Lexapro but not Zoloft.

Problem with Ejaculation - Disorder of Ejaculation is a Frequently Occurring Side Effect of Lexapro but not Zoloft.

Inability to have an Erection - Erectile Dysfunction is a Frequently Occurring Side Effect of Lexapro but not Zoloft.

Click for a searchable interactive map of all Side Effects associated with Zoloft and Lexapro.

Zoloft and Lexapro Treat 8 Conditions in Common

Obsessive Compulsive Disorder - Obsessive-Compulsive Disorder is treated by both Zoloft and Lexapro. Panic Disorder is treated by both Zoloft and Lexapro. Posttraumatic Stress Syndrome - Post Traumatic Stress Disorder is treated by both Zoloft and Lexapro. Bipolar Depression - Depression associated with Manic Depressive Disorder is treated by both Zoloft and Lexapro.

Zoloft has 13 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zoloft.

Zoloft Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Bipolar Disorder - Manic-Depression is a contraindication of Zoloft.

Neuroleptic Malignant Syndrome is a contraindication of Zoloft.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Zoloft.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Zoloft.

Upper GI Bleed - Bleeding from Stomach, Esophagus or Duodenum is a contraindication of Zoloft.

Contraindication Warnings

Disease of Liver - Liver Problems is a contraindication of Zoloft.

Hypomania - Mild Degree of Mania is a contraindication of Zoloft.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Zoloft.

Increased Risk of Bleeding is a contraindication of Zoloft.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Zoloft.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Zoloft.

Seizure Disorder - Seizures is a contraindication of Zoloft.

Weight Loss is a contraindication of Zoloft.

Lexapro has 13 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Lexapro.

Lexapro Oral Contraindications
(grouped by decreasing seriouosness level)

Relative Contraindications

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Lexapro.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Lexapro.

Upper GI Bleed - Bleeding from Stomach, Esophagus or Duodenum is a contraindication of Lexapro.

Contraindication Warnings

Bipolar Disorder - Manic-Depression is a contraindication of Lexapro.

Cardiac Disease - Heart Disease is a contraindication of Lexapro.

Disease of Liver - Liver Problems is a contraindication of Lexapro.

Epilepsy - Epileptic Seizure is a contraindication of Lexapro.

Increased Risk of Bleeding is a contraindication of Lexapro.

Neuroleptic Malignant Syndrome is a contraindication of Lexapro.

Recovery Phase Following Myocardial Infarct - Recent Heart Attack is a contraindication of Lexapro.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Lexapro.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Lexapro.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Lexapro.

Zoloft - Symptoms of overdose may include
severe dizziness, fainting.

Lexapro - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.