Compare Zoloft vs Paxil

Compare Zoloft

vs Paxil

Compare Zoloft to Paxil. To make a decision about Zoloft vs Paxil, click here for a Medication Risk Map to help you select Zoloft or Paxil

Click here for Drug Interactions and Side Effects of Zoloft.
Click here for Drug Interactions and Side Effects of Paxil.
Click here to see the effects of combining Zoloft and Paxil.

Uses of Zoloft

Zoloft is also known by the generic name Sertraline

USES:
Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

Uses of Paxil

Paxil is also known by the generic name Paroxetine Hcl

USES:
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, panic attacks, obsessive-compulsive disorder (OCD), anxiety disorders, post-traumatic stress disorder, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

SSRIs work by helping to restore the balance of certain natural substances in the brain (neurotransmitters such as serotonin). Paroxetine may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease anxiety/unreasonable fears, persistent/troubling thoughts (obsessions), and unwanted urges that keep returning (compulsions). It may decrease the number and severity of panic attacks. Paroxetine may lessen premenstrual symptoms such as irritability, increased appetite, and depression.

Zoloft and Paxil Have 11 Life Threatening (Major) Side Effects in Common

Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - Heart Throbbing or Pounding - Palpitations is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - Mild Degree of Mania - Hypomania is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of both Zoloft and Paxil.

Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of both Zoloft and Paxil.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Paxil.

Zoloft Has 14 Life Threatening (Major) Side Effects Not Found in Paxil

Critical Seriousness - Sexual Problems - Abnormal Sexual Function is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Hemorrhage is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Fever is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Discharge of Milk in Men or Women when Not Breastfeeding - Galactorrhea not associated with Childbirth is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Altered Interest in Having Sexual Intercourse - Libido Changes is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Inability to have an Erection - Erectile Dysfunction is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Breast Tenderness - Mastalgia is a Life Threatening Side Effect of Zoloft but not Paxil.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Paxil.

Paxil Has 22 Life Threatening (Major) Side Effects Not Found in Zoloft

Critical Seriousness - Muscle Weakness is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Hallucination - Hallucinations is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Increased Risk of Bleeding is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Muscle Disease - Myopathy is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Abnormally Long or Heavy Periods - Menorrhagia is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Feeling Restless - Feeling Agitated is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Muscle Pain - Myalgia is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Inflammation or Infection of Vagina - Vaginitis is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Problems with Eyesight - Visual Changes is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Widening of Blood Vessels - Vasodilation of Blood Vessels is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Difficulty Speaking - Dysarthria is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Broken Bone - Fractures is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Myoclonus is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Chest Pain is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Hyperactive Behavior - Hyperkinesis is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Sinus Irritation and Congestion - Sinusitis is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Diminished or Slow Movement - Hypokinesia is a Life Threatening Side Effect of Zoloft but not Paxil.

Critical Seriousness - Voluntary Movement Difficulty - Dyskinesia is a Life Threatening Side Effect of Zoloft but not Paxil.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Paxil.

Zoloft and Paxil Have 11 Most Frequently Occurring Side Effects in Common

Dizzy - Dizziness is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Drowsiness - Drowsy is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Diarrhea is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of both Zoloft and Paxil.

Click for a searchable interactive map of all Side Effects associated with Zoloft and Paxil.

Zoloft Has 7 Most Frequently Occurring Side Effects Not Found in Paxil

Sexual Problems - Abnormal Sexual Function is a Frequently Occurring Side Effect of Zoloft but not Paxil.

Gas - Flatulence is a Frequently Occurring Side Effect of Zoloft but not Paxil.

Altered Interest in Having Sexual Intercourse - Libido Changes is a Frequently Occurring Side Effect of Zoloft but not Paxil.

Inability to have an Erection - Erectile Dysfunction is a Frequently Occurring Side Effect of Zoloft but not Paxil.

Weight Loss is a Frequently Occurring Side Effect of Zoloft but not Paxil.

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Zoloft but not Paxil.

Low Energy - Fatigue is a Frequently Occurring Side Effect of Zoloft but not Paxil.

Click for a searchable interactive map of all Side Effects associated with Zoloft and Paxil.

Paxil Has 7 Most Frequently Occurring Side Effects Not Found in Paxil

Sexual Problems - Abnormal Sexual Function is a Frequently Occurring Side Effect of Paxil but not Zoloft.

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Paxil but not Zoloft.

Cannot Empty Bladder - Urinary Retention is a Frequently Occurring Side Effect of Paxil but not Zoloft.

Problem with Ejaculation - Disorder of Ejaculation is a Frequently Occurring Side Effect of Paxil but not Zoloft.

Difficult or Painful Urination - Dysuria is a Frequently Occurring Side Effect of Paxil but not Zoloft.

Nervous - Nervousness is a Frequently Occurring Side Effect of Paxil but not Zoloft.

Frequent Urination - Increased Urinary Frequency is a Frequently Occurring Side Effect of Paxil but not Zoloft.

Click for a searchable interactive map of all Side Effects associated with Zoloft and Paxil.

Zoloft and Paxil Treat 15 Conditions in Common

Extreme Apprehension or Fear of Social Interaction - Social Phobia is treated by both Zoloft and Paxil.

Depression is treated by both Zoloft and Paxil.

Obsessive Compulsive Disorder - Obsessive-Compulsive Disorder is treated by both Zoloft and Paxil.

Panic Disorder is treated by both Zoloft and Paxil.

Posttraumatic Stress Syndrome - Post Traumatic Stress Disorder is treated by both Zoloft and Paxil.

Premenstrual Disorder with a State of Unhappiness - Premenstrual Dysphoric Disorder is treated by both Zoloft and Paxil.

Bipolar Depression - Depression associated with Manic Depressive Disorder is treated by both Zoloft and Paxil.

Zoloft has 13 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zoloft.

Zoloft Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Bipolar Disorder - Manic-Depression is a contraindication of Zoloft.

Neuroleptic Malignant Syndrome is a contraindication of Zoloft.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Zoloft.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Zoloft.

Upper GI Bleed - Bleeding from Stomach, Esophagus or Duodenum is a contraindication of Zoloft.

Contraindication Warnings

Disease of Liver - Liver Problems is a contraindication of Zoloft.

Hypomania - Mild Degree of Mania is a contraindication of Zoloft.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Zoloft.

Increased Risk of Bleeding is a contraindication of Zoloft.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Zoloft.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Zoloft.

Seizure Disorder - Seizures is a contraindication of Zoloft.

Weight Loss is a contraindication of Zoloft.

Paxil has 15 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Paxil.

Paxil Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications

Neuroleptic Malignant Syndrome is a contraindication of Paxil.

Pregnancy is a contraindication of Paxil.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Paxil.

Relative Contraindications

Bipolar Disorder - Manic-Depression is a contraindication of Paxil.

Disease of Liver - Liver Problems is a contraindication of Paxil.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Paxil.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Paxil.

Upper GI Bleed - Bleeding from Stomach, Esophagus or Duodenum is a contraindication of Paxil.

Contraindication Warnings

Akathisia - A Feeling of Restlessness with Inability to Sit Still is a contraindication of Paxil.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Paxil.

Increased Risk of Bleeding is a contraindication of Paxil.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Paxil.

Pathological Fracture - Broken Bone due to Disease or Illness is a contraindication of Paxil.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Paxil.

Seizure Disorder - Seizures is a contraindication of Paxil.

Zoloft - Symptoms of overdose may include
severe dizziness, fainting.

Paxil - Symptoms of overdose may include
irregular heartbeat, fainting, severe dizziness, seizures.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.