Compare Zoloft vs Pristiq

Compare Zoloft

vs Pristiq

Compare Zoloft to Pristiq. To make a decision about Zoloft vs Pristiq, click here for a Medication Risk Map to help you select Zoloft or Pristiq

Click here for Drug Interactions and Side Effects of Zoloft.
Click here for Drug Interactions and Side Effects of Pristiq.
Click here to see the effects of combining Zoloft and Pristiq.

Uses of Zoloft

Zoloft is also known by the generic name Sertraline

USES:
Sertraline is used to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. It may also reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, and checking) that interfere with daily living. Sertraline is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

Uses of Pristiq

Pristiq is also known by the generic name Desvenlafaxine

USES:
Desvenlafaxine is an antidepressant (serotonin-norepinephrine reuptake inhibitor type-SNRI) used in the treatment of depression. It works by restoring the balance of natural substances (neurotransmitters such as serotonin and norepinephrine) in the brain. Desvenlafaxine may improve your mood, feelings of well-being, and energy level.

Zoloft and Pristiq Have 11 Life Threatening (Major) Side Effects in Common

Critical Seriousness - Sexual Problems - Abnormal Sexual Function is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - Itching - Pruritus of Skin is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - Mild Degree of Mania - Hypomania is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - A Feeling of Restlessness with Inability to Sit Still - Akathisia is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - Behaving with Excessive Cheerfulness and Activity - Manic Disorder is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - Serotonin Syndrome - Adverse Drug Interaction - Serotonin Syndrome is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of both Zoloft and Pristiq.

Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of both Zoloft and Pristiq.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Pristiq.

Zoloft Has 14 Life Threatening (Major) Side Effects Not Found in Pristiq

Critical Seriousness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Heart Throbbing or Pounding - Palpitations is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Hemorrhage is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Fever is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Discharge of Milk in Men or Women when Not Breastfeeding - Galactorrhea not associated with Childbirth is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Altered Interest in Having Sexual Intercourse - Libido Changes is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Inability to have an Erection - Erectile Dysfunction is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Breast Tenderness - Mastalgia is a Life Threatening Side Effect of Zoloft but not Pristiq.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Pristiq.

Pristiq Has 40 Life Threatening (Major) Side Effects Not Found in Zoloft

Critical Seriousness - Low Blood Counts due to Bone Marrow Failure - Aplastic Anemia is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Head Pain - Headache Disorder is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Cannot Empty Bladder - Urinary Retention is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Increased Risk of Bleeding is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Depression is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Disturbance in the Ability of the Eye to Focus - Accommodation Disorder is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Blurred Vision is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Interstitial Pneumonitis is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Erythema Multiforme is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Feeling Restless - Feeling Agitated is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Loss of One's Own Sense of Reality or Identity - Depersonalization is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Blood Pressure Drop Upon Standing - Orthostatic Hypotension is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Hemorrhage of Blood Under the Skin - Ecchymosis is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Enlarged Prostate - Benign Prostatic Hypertrophy is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Difficult or Painful Urination - Dysuria is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - High Cholesterol - Hypercholesterolemia is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Problems with Eyesight - Visual Changes is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Ringing in the Ears - Tinnitus is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Very Rapid Heartbeat - Torsades de Pointes - Torsades de Pointes is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Mood Changes is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Pneumonia with High Amount of Eosinophil White Blood Cells - Eosinophilic Pneumonia is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Low Blood Sugar - Hypoglycemic Disorder is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Mental Impairment is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Chest Pain is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Abnormal Heart Electrical Signals - Abnormal ECG is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Sinus Irritation and Congestion - Sinusitis is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Lockjaw - Trismus is a Life Threatening Side Effect of Zoloft but not Pristiq.

Critical Seriousness - Frequent Urination - Increased Urinary Frequency is a Life Threatening Side Effect of Zoloft but not Pristiq.

Click for a searchable interactive map of all Life Threatening Side Effects associated with Zoloft and Pristiq.

Zoloft and Pristiq Have 11 Most Frequently Occurring Side Effects in Common

Sexual Problems - Abnormal Sexual Function is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Dizzy - Dizziness is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Drowsiness - Drowsy is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Feeling Weak - General Weakness is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of both Zoloft and Pristiq.

Click for a searchable interactive map of all Side Effects associated with Zoloft and Pristiq.

Zoloft Has 7 Most Frequently Occurring Side Effects Not Found in Pristiq

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Zoloft but not Pristiq.

Gas - Flatulence is a Frequently Occurring Side Effect of Zoloft but not Pristiq.

Diarrhea is a Frequently Occurring Side Effect of Zoloft but not Pristiq.

Altered Interest in Having Sexual Intercourse - Libido Changes is a Frequently Occurring Side Effect of Zoloft but not Pristiq.

Inability to have an Erection - Erectile Dysfunction is a Frequently Occurring Side Effect of Zoloft but not Pristiq.

Weight Loss is a Frequently Occurring Side Effect of Zoloft but not Pristiq.

Low Energy - Fatigue is a Frequently Occurring Side Effect of Zoloft but not Pristiq.

Click for a searchable interactive map of all Side Effects associated with Zoloft and Pristiq.

Pristiq Has 11 Most Frequently Occurring Side Effects Not Found in Pristiq

Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Disturbance in the Ability of the Eye to Focus - Accommodation Disorder is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Blurred Vision is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Taste Problems - Dysgeusia is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Problem with Ejaculation - Disorder of Ejaculation is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Throwing Up - Vomiting is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Anxious - Anxiety is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Problems with Eyesight - Visual Changes is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Numbness and Tingling - Paresthesia is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Nervous - Nervousness is a Frequently Occurring Side Effect of Pristiq but not Zoloft.

Click for a searchable interactive map of all Side Effects associated with Zoloft and Pristiq.

Zoloft and Pristiq Treat 3 Conditions in Common

Extreme Apprehension or Fear of Social Interaction - Social Phobia is treated by both Zoloft and Pristiq. Panic Disorder is treated by both Zoloft and Pristiq.

Zoloft has 13 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Zoloft.

Zoloft Oral Contraindications
(grouped by decreasing seriousness level)

Relative Contraindications

Bipolar Disorder - Manic-Depression is a contraindication of Zoloft.

Neuroleptic Malignant Syndrome is a contraindication of Zoloft.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Zoloft.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Zoloft.

Upper GI Bleed - Bleeding from Stomach, Esophagus or Duodenum is a contraindication of Zoloft.

Contraindication Warnings

Disease of Liver - Liver Problems is a contraindication of Zoloft.

Hypomania - Mild Degree of Mania is a contraindication of Zoloft.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Zoloft.

Increased Risk of Bleeding is a contraindication of Zoloft.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Zoloft.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Zoloft.

Seizure Disorder - Seizures is a contraindication of Zoloft.

Weight Loss is a contraindication of Zoloft.

Pristiq has 24 Condition Contraindications

If you have any of these Conditions then you should carefully evaluate the risks of taking Pristiq.

Pristiq Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications

Neuroleptic Malignant Syndrome is a contraindication of Pristiq.

Serotonin Syndrome - Serotonin Syndrome - Adverse Drug Interaction is a contraindication of Pristiq.

Relative Contraindications

Bipolar Disorder - Manic-Depression is a contraindication of Pristiq.

Disease of Liver - Liver Problems is a contraindication of Pristiq.

Hemorrhage is a contraindication of Pristiq.

Hypertension - High Blood Pressure is a contraindication of Pristiq.

Hypomania - Mild Degree of Mania is a contraindication of Pristiq.

Interstitial Lung Disease - Lung Tissue Problems is a contraindication of Pristiq.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Pristiq.

Ocular Hypertension - Increased Pressure in the Eye is a contraindication of Pristiq.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Pristiq.

Severe Uncontrolled Hypertension - Severe Uncontrolled High Blood Pressure is a contraindication of Pristiq.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Pristiq.

Contraindication Warnings

Blood Coagulation Disorder - Blood Clotting Disorder is a contraindication of Pristiq.

Cerebrovascular Disorder - Any Disorder of the Blood Vessels of the Brain is a contraindication of Pristiq.

Disease of Cardiovascular System - Disease of the Heart and Blood Vessels is a contraindication of Pristiq.

Hypercholesterolemia - High Cholesterol is a contraindication of Pristiq.

Hypertriglyceridemia - High Amount of Triglyceride in the Blood is a contraindication of Pristiq.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Pristiq.

Increased Risk of Bleeding is a contraindication of Pristiq.

Manic Disorder - Behaving with Excessive Cheerfulness and Activity is a contraindication of Pristiq.

Recovery Phase Following Myocardial Infarct - Recent Heart Attack is a contraindication of Pristiq.

SIADH Syndrome - Syndrome of Inappropriate Antidiuretic Hormone Secretion is a contraindication of Pristiq.

Seizure Disorder - Seizures is a contraindication of Pristiq.

Zoloft - Symptoms of overdose may include
severe dizziness, fainting.

Pristiq - Symptoms of overdose may include
severe drowsiness, seizures, fast/irregular heartbeat.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.