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Drug Interactions and Side Effects of Avastin

Avastin has 78 Side Effects total
49 are Life Threatening
15 Occur Most Frequently

Uses of Avastin
 
Avastin is also known by the generic name Bevacizumab


USES:
This medication is a man-made antibody (IgG1) used to treat kidney, colon, and rectal cancer. Bevacizumab is also used to treat lung cancer (non-small cell type) and certain types of brain tumors. Also, cancer experts say that bevacizumab can be of benefit in treating breast cancer, however the FDA says that the risks outweigh the benefits for that disease. If you have breast cancer, talk to your doctor about the risks and benefits of bevacizumab. This drug works by blocking a certain protein (vascular endothelial growth factor-VEGF) thereby decreasing the blood supply to the tumor and slowing tumor growth.


Avastin has 49 Life Threatening (Critical) Side Effects
 
Critical Seriousness - A Rupture in the Wall of the Stomach or Intestine - Gastrointestinal Perforation is a Life Threatening Side Effect of Avastin
Critical Seriousness - Abnormal Connection Between Esophagus and Windpipe - Tracheoesophageal Fistula is a Life Threatening Side Effect of Avastin
Critical Seriousness - Abnormal Connection Between Two Body Organs - Internal Fistula Formation is a Life Threatening Side Effect of Avastin
Critical Seriousness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Avastin
Critical Seriousness - Acquired Decrease of All Cells in the Blood - Pancytopenia is a Life Threatening Side Effect of Avastin
Critical Seriousness - Acute Blood Clot in an Artery - Acute Arterial Thromboembolism is a Life Threatening Side Effect of Avastin
Critical Seriousness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Avastin
Critical Seriousness - An Abnormal Connection Between the Stomach and Intestine - Gastrointestinal Fistula is a Life Threatening Side Effect of Avastin
Critical Seriousness - Bleeding Not Related to Menstrual Period - Metrorrhagia is a Life Threatening Side Effect of Avastin
Critical Seriousness - Bleeding from the Lungs - Pulmonary Hemorrhage is a Life Threatening Side Effect of Avastin
Critical Seriousness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Avastin
Critical Seriousness - Blocked Bowels with No Movement - Ileus is a Life Threatening Side Effect of Avastin
Critical Seriousness - Blood Clot Formation in Veins - Venous Thrombosis is a Life Threatening Side Effect of Avastin
Critical Seriousness - Blood Clot in a Deep Vein - Deep Venous Thrombosis is a Life Threatening Side Effect of Avastin
Critical Seriousness - Brain-Capillary Leak Syndrome - Reversible Posterior Leukoencephalopathy Syndrome is a Life Threatening Side Effect of Avastin
Critical Seriousness - Chest Pain is a Life Threatening Side Effect of Avastin
Critical Seriousness - Chronic Heart Failure is a Life Threatening Side Effect of Avastin
Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Avastin
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Avastin
Critical Seriousness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Avastin
Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Avastin
Critical Seriousness - Elevation of Proteins in the Urine - Proteinuria is a Life Threatening Side Effect of Avastin
Critical Seriousness - Extreme Loss of Body Water - Dehydration is a Life Threatening Side Effect of Avastin
Critical Seriousness - Extremely High Blood Pressure - Hypertensive Emergencies is a Life Threatening Side Effect of Avastin
Critical Seriousness - Feeling Faint - Fainting is a Life Threatening Side Effect of Avastin
Critical Seriousness - Gangrene of Intestine caused by Blood Supply Problem - Intestinal Ischemic Necrosis is a Life Threatening Side Effect of Avastin
Critical Seriousness - Heart Attack - Myocardial Infarction is a Life Threatening Side Effect of Avastin
Critical Seriousness - Hemorrhage in the Subarachnoid Space of the Brain - Subarachnoid Hemorrhage is a Life Threatening Side Effect of Avastin
Critical Seriousness - Hemorrhage is a Life Threatening Side Effect of Avastin
Critical Seriousness - High Amount of Bilirubin in the Blood - Hyperbilirubinemia is a Life Threatening Side Effect of Avastin
Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Avastin
Critical Seriousness - Impaired Wound Healing is a Life Threatening Side Effect of Avastin
Critical Seriousness - Increased Pressure of Pulmonary Circulation - Pulmonary Hypertension is a Life Threatening Side Effect of Avastin
Critical Seriousness - Inflammation of the Large Intestine - Colitis is a Life Threatening Side Effect of Avastin
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Avastin
Critical Seriousness - Low Amount of Potassium in the Blood - Hypokalemia is a Life Threatening Side Effect of Avastin
Critical Seriousness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of Avastin
Critical Seriousness - Nephrotic Syndrome is a Life Threatening Side Effect of Avastin
Critical Seriousness - Nosebleed - Epistaxis is a Life Threatening Side Effect of Avastin
Critical Seriousness - Painful, Red or Swollen Mouth - Stomatitis is a Life Threatening Side Effect of Avastin
Critical Seriousness - Perforation of the Wall that Divides the Nose - Nasal Septal Perforation is a Life Threatening Side Effect of Avastin
Critical Seriousness - Problems with Post-Surgery Wound Healing - Surgical Wound Dehiscence is a Life Threatening Side Effect of Avastin
Critical Seriousness - Skin Discoloration - Dyschromia is a Life Threatening Side Effect of Avastin
Critical Seriousness - Skin Rash with Sloughing - Exfoliative Dermatitis is a Life Threatening Side Effect of Avastin
Critical Seriousness - Skin Ulcer is a Life Threatening Side Effect of Avastin
Critical Seriousness - Stomach or Intestine Blockage - Gastrointestinal Obstruction is a Life Threatening Side Effect of Avastin
Critical Seriousness - Stroke caused by Bleeding in the Brain - Hemorrhagic Stroke is a Life Threatening Side Effect of Avastin
Critical Seriousness - Thrombotic Thrombocytopenic Purpura is a Life Threatening Side Effect of Avastin
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Avastin

Avastin has 15 Most Frequently Occurring Side Effects
 
Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Frequently Occurring Side Effect of Avastin
Blood Clot Formation in Veins - Venous Thrombosis is a Frequently Occurring Side Effect of Avastin
Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Frequently Occurring Side Effect of Avastin
Decreased White Blood Cells - Leukopenia is a Frequently Occurring Side Effect of Avastin
Diarrhea is a Frequently Occurring Side Effect of Avastin
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Avastin
Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Avastin
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Avastin
High Blood Pressure - Hypertension is a Frequently Occurring Side Effect of Avastin
Incomplete or Infrequent Bowel Movements - Constipation is a Frequently Occurring Side Effect of Avastin
Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Avastin
Painful, Red or Swollen Mouth - Stomatitis is a Frequently Occurring Side Effect of Avastin
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Avastin
Taste Problems - Dysgeusia is a Frequently Occurring Side Effect of Avastin
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Avastin

Avastin Drug-Drug Interactions
 
Avastin has interactions of severe seriousness with 4 drug(s):
Avastin has 1 severe interactions with Efalizumab. Click here to see them
Avastin has 1 severe interactions with Natalizumab. Click here to see them
Avastin has 1 severe interactions with Raptiva. Click here to see them
Avastin has 1 severe interactions with Tysabri. Click here to see them

Avastin has interactions of serious seriousness with 2 drug(s).

Avastin has interactions of moderate seriousness with 2 drug(s).

Avastin has interactions of unknown seriousness with 0 drug(s).

Avastin has 29 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Avastin.

Avastin Intravenous Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Acute Arterial Thromboembolism - Acute Blood Clot in an Artery is a contraindication of Avastin.

Gastrointestinal Fistula - An Abnormal Connection Between the Stomach and Intestine is a contraindication of Avastin.

Gastrointestinal Perforation - A Rupture in the Wall of the Stomach or Intestine is a contraindication of Avastin.

Hypertensive Emergencies - Extremely High Blood Pressure is a contraindication of Avastin.

Intra-Abdominal Abscess - Abscess Within the Abdomen is a contraindication of Avastin.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Avastin.

Nephrotic Syndrome is a contraindication of Avastin.

Reversible Posterior Leukoencephalopathy Syndrome - Brain-Capillary Leak Syndrome is a contraindication of Avastin.

Severe Uncontrolled Hypertension - Severe Uncontrolled High Blood Pressure is a contraindication of Avastin.

Surgical Procedure - Recent Operation is a contraindication of Avastin.

Surgical Wound Dehiscence - Problems with Post-Surgery Wound Healing is a contraindication of Avastin.

Tracheoesophageal Fistula - Abnormal Connection Between Esophagus and Windpipe is a contraindication of Avastin.

Relative Contraindications 

Acute Thromboembolic Stroke is a contraindication of Avastin.

Angina is a contraindication of Avastin.

Chemotherapy-Induced Neutropenia - Decrease of Neutrophils in the Blood from Cancer Chemotherapy is a contraindication of Avastin.

Chronic Heart Failure is a contraindication of Avastin.

Erosive Esophagitis - Inflammation of the Esophagus with Erosion is a contraindication of Avastin.

Hemoptysis - Coughing Up Blood is a contraindication of Avastin.

Hemorrhage is a contraindication of Avastin.

Impaired Wound Healing is a contraindication of Avastin.

Myocardial Infarction - Heart Attack is a contraindication of Avastin.

Pulmonary Hemorrhage - Bleeding from the Lungs is a contraindication of Avastin.

Severe Neutropenic Disorder - Severely Decreased Levels of Neutrophils in the Blood is a contraindication of Avastin.

Thromboembolic Disorder - Obstruction of a Blood Vessel by a Blood Clot is a contraindication of Avastin.

Transient Cerebral Ischemia - Transient Ischemic Attack is a contraindication of Avastin.

Venous Thrombosis - Blood Clot Formation in Veins is a contraindication of Avastin.

Contraindication Warnings 

Hypertension - High Blood Pressure is a contraindication of Avastin.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Avastin.

Proteinuria - Elevation of Proteins in the Urine is a contraindication of Avastin.

Avastin has 2 related brands and strengths:
 
Avastin 25 Mg/Ml Iv

Bevacizumab 25 Mg/Ml Iv

Avastin - Symptoms of overdose may include
severe headache.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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