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Drug Interactions and Side Effects of Combivir

Combivir has 45 Side Effects total
26 are Life Threatening
7 Occur Most Frequently

Uses of Combivir
 
Combivir is also known by the generic name Lamivudine-Zidovudine


USES:
This product contains 2 drugs:
lamivudine and zidovudine. It is used with other medications to help control your HIV infection, thereby improving your quality of life. It helps to decrease the amount of HIV in your body so your immune system can work better. This product also lowers your risk of getting HIV disease complications (such as new infections, cancer). Both lamivudine and zidovudine belong to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).

Lamivudine/zidovudine is not a cure for HIV infection and it does not prevent the spread of HIV to others through sexual contact or blood contamination (such as sharing used needles).


Combivir has 26 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Combivir
Critical Seriousness - Anemia is a Life Threatening Side Effect of Combivir
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Combivir
Critical Seriousness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Combivir
Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Combivir
Critical Seriousness - Disease of the Muscle of the Heart with Enlargement - Cardiomyopathy is a Life Threatening Side Effect of Combivir
Critical Seriousness - Disease of the Nerves - Neuropathy is a Life Threatening Side Effect of Combivir
Critical Seriousness - Enlarged Fatty Liver - Steatosis of Liver is a Life Threatening Side Effect of Combivir
Critical Seriousness - Enlarged Spleen - Hypersplenism is a Life Threatening Side Effect of Combivir
Critical Seriousness - Erythema Multiforme is a Life Threatening Side Effect of Combivir
Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Combivir
Critical Seriousness - High Blood Sugar - Hyperglycemia is a Life Threatening Side Effect of Combivir
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Combivir
Critical Seriousness - Increased Blood Acidity due to High Levels of Lactic Acid - Lactic Acidosis is a Life Threatening Side Effect of Combivir
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Combivir
Critical Seriousness - Muscle Disease - Myopathy is a Life Threatening Side Effect of Combivir
Critical Seriousness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Combivir
Critical Seriousness - Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Life Threatening Side Effect of Combivir
Critical Seriousness - Painful, Red or Swollen Mouth - Stomatitis is a Life Threatening Side Effect of Combivir
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Combivir
Critical Seriousness - Seizures - Seizure Disorder is a Life Threatening Side Effect of Combivir
Critical Seriousness - Serious Muscle Damage that may Lead to Kidney Failure - Rhabdomyolysis is a Life Threatening Side Effect of Combivir
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Combivir
Critical Seriousness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Combivir
Critical Seriousness - Vasculitis is a Life Threatening Side Effect of Combivir
Critical Seriousness - Wheezing is a Life Threatening Side Effect of Combivir

Combivir has 7 Most Frequently Occurring Side Effects
 
Abnormal Fat Distribution associated with HIV - Lipodystrophy associated with Human Immunodeficiency Virus Infection is a Frequently Occurring Side Effect of Combivir
Acute Inflammation of the Pancreas - Acute Pancreatitis is a Frequently Occurring Side Effect of Combivir
Decreased White Blood Cells - Leukopenia is a Frequently Occurring Side Effect of Combivir
Diarrhea is a Frequently Occurring Side Effect of Combivir
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Combivir
Numbness and Tingling - Paresthesia is a Frequently Occurring Side Effect of Combivir
Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Frequently Occurring Side Effect of Combivir

Combivir Drug-Drug Interactions
 
Combivir has interactions of severe seriousness with 4 drug(s):
Combivir has 1 severe interactions with Hivid. Click here to see them
Combivir has 1 severe interactions with Neutrexin. Click here to see them
Combivir has 1 severe interactions with Trimetrexate. Click here to see them
Combivir has 1 severe interactions with Zalcitabine. Click here to see them

Combivir has interactions of serious seriousness with 31 drug(s).

Combivir has interactions of moderate seriousness with 18 drug(s).

Combivir has interactions of unknown seriousness with 0 drug(s).

Combivir has 18 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Combivir.

Combivir Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Combivir.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Combivir.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Combivir.

Lactic Acidosis - Increased Blood Acidity due to High Levels of Lactic Acid is a contraindication of Combivir.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Combivir.

Steatosis of Liver - Enlarged Fatty Liver is a contraindication of Combivir.

Relative Contraindications 

Anemia is a contraindication of Combivir.

Bone Marrow Depression - Decreased Function of Bone Marrow is a contraindication of Combivir.

Hepatomegaly - Enlarged Liver is a contraindication of Combivir.

Myopathy - Muscle Disease is a contraindication of Combivir.

Myositis - Muscle Inflammation is a contraindication of Combivir.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Combivir.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Combivir.

Contraindication Warnings 

Disease of Liver - Liver Problems is a contraindication of Combivir.

Drug Resistance to Anti-retroviral Therapy is a contraindication of Combivir.

Obesity - Overweight is a contraindication of Combivir.

Renal Disease - Kidney Disease is a contraindication of Combivir.

Toxic Amblyopia - Vision Changes caused by Medications is a contraindication of Combivir.

Combivir has 2 related brands and strengths:
 
Combivir 150 Mg-300 Mg Tab

Lamivudine-Zidovudine 150 Mg-300 Mg Tab

Combivir - Symptoms of overdose may include
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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