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Drug Interactions and Side Effects of Coumadin

Coumadin has 49 Side Effects total
36 are Life Threatening
0 Occur Most Frequently

Uses of Coumadin
 
Coumadin is also known by the generic name Warfarin


USES:
This medication is used to treat blood clots (such as in deep vein thrombosis-DVT or pulmonary embolus-PE) and/or to prevent new clots from forming in your body. Preventing harmful blood clots helps to reduce the risk of a stroke or heart attack. Conditions that increase your risk of developing blood clots include a certain type of irregular heart rhythm (atrial fibrillation), heart valve replacement, recent heart attack, and certain surgeries (such as hip/knee replacement).

Warfarin is commonly called a "blood thinner," but the more correct term is "anticoagulant." It helps to keep blood flowing smoothly in your body by decreasing the amount of certain substances (clotting proteins) in your blood.


Coumadin has 36 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Adrenal Hemorrhage is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Bloody Urine - Hematuria is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Canker Sore - Aphthous Stomatitis is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Diarrhea is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Feel Like Throwing Up - Nausea is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Foot Pain - Feet Pain is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Gangrene is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Hemorrhage is a Life Threatening Side Effect of Coumadin
Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Increased Risk of Bleeding is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Inflammation of the Liver with Stoppage of Bile Flow - Cholestatic Hepatitis is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Itching - Pruritus of Skin is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Kidney Disease - Renal Disease is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Lack of Blood Supply to the Brain - Cerebral Ischemia is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Muscle Pain - Myalgia is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Obstruction of Blood Vessel caused by a Fat Globule - Cholesterol Embolism is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Pain in Arms or Legs - Limb Pain is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Pancreatitis is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Problem with Adrenal Gland - Acute Adrenocortical Insufficiency is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Purplish Discoloration of the Skin that Looks Like Netting - Livedo Reticularis is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Stomach Cramps - Abdominal Pain with Cramps is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Throwing Up - Vomiting is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Tissue Death - Tissue Necrosis is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Ulcer of the Throat - Throat Ulceration is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Vasculitis is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Visible Water Retention - Edema is a Life Threatening Side Effect of Coumadin
Critical Seriousness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Coumadin

Coumadin has 0 Most Frequently Occurring Side Effects
 

Coumadin Drug-Drug Interactions
 
Coumadin has interactions of severe seriousness with 6 drug(s):
Coumadin has 1 severe interactions with Gleevec. Click here to see them
Coumadin has 1 severe interactions with Imatinib. Click here to see them
Coumadin has 1 severe interactions with Mifeprex. Click here to see them
Coumadin has 1 severe interactions with Mifepristone. Click here to see them
Coumadin has 1 severe interactions with Tenecteplase. Click here to see them
Coumadin has 1 severe interactions with Tnkase. Click here to see them

Coumadin has interactions of serious seriousness with 2670 drug(s).

Coumadin has interactions of moderate seriousness with 2779 drug(s).

Coumadin has interactions of unknown seriousness with 759 drug(s).

Coumadin has 60 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Coumadin.

Coumadin Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Aortic Aneurysm with Dissection - Bulge and Tear of the Aorta Blood Vessel Wall is a contraindication of Coumadin.

Bacterial Endocarditis - Bacterial Infection of Heart Valve is a contraindication of Coumadin.

Blood Coagulation Disorder - Blood Clotting Disorder is a contraindication of Coumadin.

Brain Aneurysm - Balloon-Like Swelling of an Artery of the Brain is a contraindication of Coumadin.

Cerebrovascular Hemorrhage - Hemorrhage in the Brain is a contraindication of Coumadin.

Eclampsia of Pregnancy - Seizures with Pregnancy is a contraindication of Coumadin.

Gastrointestinal Hemorrhage - Bleeding of the Stomach or Intestines is a contraindication of Coumadin.

Gastrointestinal Ulcer - Stomach or Intestinal Ulcer is a contraindication of Coumadin.

Genitourinary Tract Hemorrhage - Bleeding from the Genitourinary System is a contraindication of Coumadin.

Hemorrhage is a contraindication of Coumadin.

Internal Hemorrhage - Internal Bleeding is a contraindication of Coumadin.

Open Procedure on Central Nervous System - Operation on the Nervous System is a contraindication of Coumadin.

Pericardial Effusion - Fluid in the Covering of the Heart or Pericardium is a contraindication of Coumadin.

Pericarditis - Inflammation of the Covering of the Heart or Pericardium is a contraindication of Coumadin.

Pregnancy is a contraindication of Coumadin.

Respiratory Tract Hemorrhage - Bleeding from the Respiratory Tract is a contraindication of Coumadin.

Severe Uncontrolled Hypertension - Severe Uncontrolled High Blood Pressure is a contraindication of Coumadin.

Spinal Anesthesia - Local Anesthesia Injected into Spine is a contraindication of Coumadin.

Spinal Puncture - Spinal Tap is a contraindication of Coumadin.

Surgical Procedure on Eye Proper - Eye Surgery is a contraindication of Coumadin.

Threatened Abortion - Possibility of Having a Miscarriage is a contraindication of Coumadin.

Relative Contraindications 

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Coumadin.

Cerebrovascular Disorder - Any Disorder of the Blood Vessels of the Brain is a contraindication of Coumadin.

Cholesterol Embolism - Obstruction of Blood Vessel caused by a Fat Globule is a contraindication of Coumadin.

Gangrene is a contraindication of Coumadin.

Heparin-Induced Thrombocytopenia - Decreased Platelets due to the Medication Heparin is a contraindication of Coumadin.

Increased Risk of Bleeding is a contraindication of Coumadin.

Indwelling Vascular Catheter - Patient with Catheter in the Vascular System is a contraindication of Coumadin.

Moderate Hypertension - Moderate High Blood Pressure is a contraindication of Coumadin.

Polycythemia Vera - Increased Red Blood Cells is a contraindication of Coumadin.

Protein C Deficiency Disease is a contraindication of Coumadin.

Psychotic Disorder - Mental Disorder with Loss of Normal Personality & Reality is a contraindication of Coumadin.

Renal Disease with Moderate to Severe Function Impairment - Moderate to Severe Kidney Impairment is a contraindication of Coumadin.

Secondary Uterine Inertia is a contraindication of Coumadin.

Severe Diabetes Mellitus - Severe Form of Diabetes is a contraindication of Coumadin.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Coumadin.

Severe and Chronic Diarrhea - Serious Loose Stools Lasting a Long Time is a contraindication of Coumadin.

Surgical Procedure - Recent Operation is a contraindication of Coumadin.

Tissue Necrosis - Tissue Death is a contraindication of Coumadin.

Trauma - Injury is a contraindication of Coumadin.

Tropical Sprue is a contraindication of Coumadin.

Vasculitis is a contraindication of Coumadin.

Vitamin K Deficiency - Inadequate Vitamin K is a contraindication of Coumadin.

Contraindication Warnings 

Anemia is a contraindication of Coumadin.

Biliary Obstruction - Blockage of a Bile Duct is a contraindication of Coumadin.

Bleeding Risk Associated with Vitamin-K-Epoxide Reductase (Warfarin-Sensitive) Gene is a contraindication of Coumadin.

Connective Tissue Disease - Disorder of the Connective Tissue is a contraindication of Coumadin.

Disease of Liver - Liver Problems is a contraindication of Coumadin.

Edema - Visible Water Retention is a contraindication of Coumadin.

Fever is a contraindication of Coumadin.

Hyperlipidemia - High Amount of Fats in the Blood is a contraindication of Coumadin.

Hyperthyroidism - Overactive Thyroid Gland is a contraindication of Coumadin.

Hypothyroidism - Underactive Thyroid is a contraindication of Coumadin.

Malignancy - Malignant Tumor or Cancer is a contraindication of Coumadin.

Nephrotic Syndrome is a contraindication of Coumadin.

Nutritional Disorder - Poor Nutrition is a contraindication of Coumadin.

Poor Metabolizer due to Cytochrome p450 CYP2C9 Variant is a contraindication of Coumadin.

Severe Diarrhea is a contraindication of Coumadin.

Steatorrhea - Bowel Movements Containing Much Fat is a contraindication of Coumadin.

Viral Hepatitis - Viral Infection of the Liver is a contraindication of Coumadin.

Coumadin has 29 related brands and strengths:
 
Coumadin 1 Mg Tab

Coumadin 10 Mg Tab

Coumadin 2 Mg Tab

Coumadin 2.5 Mg Tab

Coumadin 3 Mg Tab

Coumadin 4 Mg Tab

Coumadin 5 Mg Iv Solution

Coumadin 5 Mg Tab

Coumadin 6 Mg Tab

Coumadin 7.5 Mg Tab

Jantoven 1 Mg Tab

Jantoven 10 Mg Tab

Jantoven 2 Mg Tab

Jantoven 2.5 Mg Tab

Jantoven 3 Mg Tab

Jantoven 4 Mg Tab

Jantoven 5 Mg Tab

Jantoven 6 Mg Tab

Jantoven 7.5 Mg Tab

Warfarin 1 Mg Tab

Warfarin 10 Mg Tab

Warfarin 2 Mg Tab

Warfarin 2.5 Mg Tab

Warfarin 3 Mg Tab

Warfarin 4 Mg Tab

Warfarin 5 Mg Iv Solution

Warfarin 5 Mg Tab

Warfarin 6 Mg Tab

Warfarin 7.5 Mg Tab

Coumadin - Symptoms of overdose may include
bloody/black/tarry stools, pink/dark urine, unusual/prolonged bleeding.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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