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Drug Interactions and Side Effects of Depakote

Depakote has 49 Side Effects total
20 are Life Threatening
17 Occur Most Frequently

Uses of Depakote
 
Depakote is also known by the generic name Divalproex


USES:
This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.


Depakote has 20 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Depakote
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Depakote
Critical Seriousness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Depakote
Critical Seriousness - Decrease in the Ability of Platelet Cells to Clot - Platelet Aggregation Inhibition is a Life Threatening Side Effect of Depakote
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Depakote
Critical Seriousness - Double Vision - Diplopia is a Life Threatening Side Effect of Depakote
Critical Seriousness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Depakote
Critical Seriousness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Depakote
Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Depakote
Critical Seriousness - High Amount of Ammonium in the Blood - Hyperammonemia is a Life Threatening Side Effect of Depakote
Critical Seriousness - Involuntary Eye Movement - Nystagmus is a Life Threatening Side Effect of Depakote
Critical Seriousness - Low Body Temperature - Hypothermia is a Life Threatening Side Effect of Depakote
Critical Seriousness - Mental Impairment is a Life Threatening Side Effect of Depakote
Critical Seriousness - Mood Changes is a Life Threatening Side Effect of Depakote
Critical Seriousness - Problem Behavior - Behavioral Disorders is a Life Threatening Side Effect of Depakote
Critical Seriousness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Depakote
Critical Seriousness - Seeing Spots - Visual Disturbance of Seeing Spots is a Life Threatening Side Effect of Depakote
Critical Seriousness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Depakote
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Depakote
Critical Seriousness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Depakote

Depakote has 17 Most Frequently Occurring Side Effects
 
Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Depakote
Diarrhea is a Frequently Occurring Side Effect of Depakote
Dizzy - Dizziness is a Frequently Occurring Side Effect of Depakote
Drowsiness - Drowsy is a Frequently Occurring Side Effect of Depakote
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Depakote
Hair Loss - Alopecia is a Frequently Occurring Side Effect of Depakote
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Depakote
Infection is a Frequently Occurring Side Effect of Depakote
Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Depakote
Irregular Periods - Irregular Menstrual Periods is a Frequently Occurring Side Effect of Depakote
Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Depakote
Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Depakote
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Depakote
Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Depakote
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Depakote
Weight Gain is a Frequently Occurring Side Effect of Depakote
Weight Loss is a Frequently Occurring Side Effect of Depakote

Depakote Drug-Drug Interactions
 
Depakote has interactions of severe seriousness with 0 drug(s):

Depakote has interactions of serious seriousness with 24 drug(s).

Depakote has interactions of moderate seriousness with 1075 drug(s).

Depakote has interactions of unknown seriousness with 11 drug(s).

Depakote has 16 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Depakote.

Depakote Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Depakote.

Carbamyl Phosphate Synthetase Deficiency - Inherited Deficiency of Carbamyl Phosphate Synthetase is a contraindication of Depakote.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Depakote.

Disease of Liver - Liver Problems is a contraindication of Depakote.

Ornithine Carbamyltransferase Deficiency is a contraindication of Depakote.

Pregnancy is a contraindication of Depakote.

Relative Contraindications 

Hyperammonemia - High Amount of Ammonium in the Blood is a contraindication of Depakote.

Porphyria is a contraindication of Depakote.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Depakote.

Contraindication Warnings 

Blood Dyscrasias - Blood Disorder is a contraindication of Depakote.

Depression is a contraindication of Depakote.

Hypoalbuminemia - Low Amount of Albumin Proteins in the Blood is a contraindication of Depakote.

Organic Mental Disorder - Dysfunction of the Brain is a contraindication of Depakote.

Renal Disease - Kidney Disease is a contraindication of Depakote.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Depakote.

Valproic Acid Toxicity - Poisoning by Drug Valproic Acid is a contraindication of Depakote.

Depakote has 12 related brands and strengths:
 
Depakote 125 Mg Tab

Depakote 250 Mg Tab

Depakote 500 Mg Tab

Depakote Er 250 Mg 24 Hr Tab

Depakote Er 500 Mg 24 Hr Tab

Depakote Sprinkles 125 Mg Sprinkle Cap

Divalproex 125 Mg Sprinkle Cap

Divalproex 125 Mg Tab, Delayed Release

Divalproex 250 Mg Tab, Delayed Release

Divalproex 500 Mg Tab, Delayed Release

Divalproex Er 250 Mg 24 Hr Tab

Divalproex Er 500 Mg 24 Hr Tab

Depakote - Symptoms of overdose may include
excessive drowsiness, coma, irregular/slowed/skipped heart beats (heart block).

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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