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Drug Interactions and Side Effects of Gleevec

Gleevec has 112 Side Effects total
63 are Life Threatening
26 Occur Most Frequently

Uses of Gleevec
 
Gleevec is also known by the generic name Imatinib


USES:
This medication is used to treat certain types of cancer (e.g., chronic myeloid leukemia, gastrointestinal stromal tumors, and myelodysplastic/myeloproliferative diseases). Imatinib works by stopping or slowing the growth of cancer cells (tumors). It also works by causing cancer cells to die.


Gleevec has 63 Life Threatening (Critical) Side Effects
 
Critical Seriousness - A Rupture in the Wall of the Stomach or Intestine - Gastrointestinal Perforation is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Abnormally Low Blood Pressure - Hypotension is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Acute Kidney Disease - Acute Renal Disease is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Anemia is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Ascites is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Blocked Bowels with No Movement - Ileus is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Blood Circulation Failure due to Serious Heart Condition - Cardiogenic Shock is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Burning Stomach - Gastritis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Canker Sore - Aphthous Stomatitis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Chest Pain is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Chronic Heart Failure is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Confused - Impaired Cognition is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Depression is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Erythema Multiforme is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Escape of Fluid into the Lungs - Pleural Effusions is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Failure of the Left Ventricle of the Heart - Left Ventricular Failure is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Fast Heartbeat - Tachyarrhythmia is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Fingernail and/or Toenail Disease - Nail Disorders is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Fit - Tonic Clonic Seizure is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Fluid Accumulation Around the Eye - Periorbital Edema is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Fluid Accumulation in the Brain - Cerebral Edema is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Fluid in the Covering of the Heart or Pericardium - Pericardial Effusion is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Fluid in the Lungs - Pulmonary Edema is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Heart Compression caused by Excess Fluid in the Covering - Pericardial Tamponade is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Heart Failure is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Hemorrhage from the Conjunctiva of the Eye - Conjunctival Hemorrhage is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Hemorrhage of the Vitreous of the Eye - Vitreous Hemorrhage is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Hemorrhage is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - High Amount of Bilirubin in the Blood - Hyperbilirubinemia is a Life Threatening Side Effect of Gleevec
Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Gleevec
Critical Seriousness - High Pressure Within the Skull - Intracranial Hypertension is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Increased Pressure in Eyes - Glaucoma is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Inflammation of the Covering of the Heart or Pericardium - Pericarditis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Inflammation of the Large Intestine - Colitis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Inflammation of the Lining of the Stomach and Intestines - Gastroenteritis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Inflammation of the Skin with Blisters - Bullous Dermatitis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Large Purple or Brown Skin Blotches - Purpura is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Liver Failure - Hepatic Failure is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Low Amount of Potassium in the Blood - Hypokalemia is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Macular Swelling and Degeneration of the Eye - Cystoid Macular Edema is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Optic Disk Edema - Papilledema is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Pink Eye - Conjunctivitis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Pneumonia is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Psoriasis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Retinal Hemorrhage is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Skin Discoloration - Dyschromia is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Skin Rash with Sloughing - Exfoliative Dermatitis is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Stomach Ulcer - Gastric Ulcer is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Sweet's Disease - Sweet's Syndrome is a Life Threatening Side Effect of Gleevec
Critical Seriousness - The Flu - Influenza is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Tumor Bleeding - Tumor Hemorrhage is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Visible Water Retention - Edema is a Life Threatening Side Effect of Gleevec
Critical Seriousness - Water Retention - Body Fluid Retention is a Life Threatening Side Effect of Gleevec

Gleevec has 26 Most Frequently Occurring Side Effects
 
Acute Infection of the Nose, Throat or Sinus - Upper Respiratory Infection is a Frequently Occurring Side Effect of Gleevec
Anemia is a Frequently Occurring Side Effect of Gleevec
Ascites is a Frequently Occurring Side Effect of Gleevec
Backache - Back Pain is a Frequently Occurring Side Effect of Gleevec
Bleeding of the Stomach or Intestines - Gastrointestinal Hemorrhage is a Frequently Occurring Side Effect of Gleevec
Chills is a Frequently Occurring Side Effect of Gleevec
Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Gleevec
Cramps is a Frequently Occurring Side Effect of Gleevec
Decreased Blood Platelets - Thrombocytopenic Disorder is a Frequently Occurring Side Effect of Gleevec
Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Frequently Occurring Side Effect of Gleevec
Diarrhea is a Frequently Occurring Side Effect of Gleevec
Dizzy - Dizziness is a Frequently Occurring Side Effect of Gleevec
Escape of Fluid into the Lungs - Pleural Effusions is a Frequently Occurring Side Effect of Gleevec
Excessive Watery Eyes - Eye Tearing is a Frequently Occurring Side Effect of Gleevec
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Gleevec
Fever is a Frequently Occurring Side Effect of Gleevec
Fluid in the Covering of the Heart or Pericardium - Pericardial Effusion is a Frequently Occurring Side Effect of Gleevec
Fluid in the Lungs - Pulmonary Edema is a Frequently Occurring Side Effect of Gleevec
Gas - Flatulence is a Frequently Occurring Side Effect of Gleevec
Hemorrhage is a Frequently Occurring Side Effect of Gleevec
Muscle Pain - Myalgia is a Frequently Occurring Side Effect of Gleevec
Rash - Skin Rash is a Frequently Occurring Side Effect of Gleevec
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Gleevec
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Gleevec
Visible Water Retention - Edema is a Frequently Occurring Side Effect of Gleevec
Water Retention - Body Fluid Retention is a Frequently Occurring Side Effect of Gleevec

Gleevec Drug-Drug Interactions
 
Gleevec has interactions of severe seriousness with 13 drug(s):
Gleevec has 1 severe interactions with Anisindione. Click here to see them
Gleevec has 1 severe interactions with Athrombin-K. Click here to see them
Gleevec has 1 severe interactions with Coufarin. Click here to see them
Gleevec has 1 severe interactions with Coumadin. Click here to see them
Gleevec has 1 severe interactions with Efalizumab. Click here to see them
Gleevec has 1 severe interactions with Jantoven. Click here to see them
Gleevec has 1 severe interactions with Miradon. Click here to see them
Gleevec has 1 severe interactions with Natalizumab. Click here to see them
Gleevec has 1 severe interactions with Panwarfin. Click here to see them
Gleevec has 1 severe interactions with Raptiva. Click here to see them
Gleevec has 1 severe interactions with Sofarin. Click here to see them
Gleevec has 1 severe interactions with Tysabri. Click here to see them
Gleevec has 1 severe interactions with Warfarin. Click here to see them

Gleevec has interactions of serious seriousness with 316 drug(s).

Gleevec has interactions of moderate seriousness with 50 drug(s).

Gleevec has interactions of unknown seriousness with 0 drug(s).

Gleevec has 35 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Gleevec.

Gleevec Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Gleevec.

Pregnancy is a contraindication of Gleevec.

Relative Contraindications 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Gleevec.

Anemia is a contraindication of Gleevec.

Ascites is a contraindication of Gleevec.

Body Fluid Retention - Water Retention is a contraindication of Gleevec.

Cardiogenic Shock - Blood Circulation Failure due to Serious Heart Condition is a contraindication of Gleevec.

Cerebral Edema - Fluid Accumulation in the Brain is a contraindication of Gleevec.

Chronic Heart Failure is a contraindication of Gleevec.

Chronic Heart Failure Following Myocardial Infarction - Heart Failure After a Heart Attack is a contraindication of Gleevec.

Edema - Visible Water Retention is a contraindication of Gleevec.

Hyperbilirubinemia - High Amount of Bilirubin in the Blood is a contraindication of Gleevec.

Left Ventricular Failure - Failure of the Left Ventricle of the Heart is a contraindication of Gleevec.

Neutropenic Disorder - Decreased Neutrophils a Type of White Blood Cell is a contraindication of Gleevec.

Pericardial Effusion - Fluid in the Covering of the Heart or Pericardium is a contraindication of Gleevec.

Pleural Effusions - Escape of Fluid into the Lungs is a contraindication of Gleevec.

Pulmonary Edema - Fluid in the Lungs is a contraindication of Gleevec.

Purpura - Large Purple or Brown Skin Blotches is a contraindication of Gleevec.

Renal Disease - Kidney Disease is a contraindication of Gleevec.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Gleevec.

Contraindication Warnings 

Congenital Heart Disease - Heart Disease Present at Birth is a contraindication of Gleevec.

Coronary Artery Disease - Disease of the Arteries of the Heart is a contraindication of Gleevec.

Diabetes Mellitus - Diabetes is a contraindication of Gleevec.

Disease of Liver - Liver Problems is a contraindication of Gleevec.

Gastrointestinal Hemorrhage - Bleeding of the Stomach or Intestines is a contraindication of Gleevec.

Gastrointestinal Perforation - A Rupture in the Wall of the Stomach or Intestine is a contraindication of Gleevec.

Hemorrhage is a contraindication of Gleevec.

Hypertension - High Blood Pressure is a contraindication of Gleevec.

Hypophosphatemia - Low Amount of Phosphate in the Blood is a contraindication of Gleevec.

Hypothyroidism - Underactive Thyroid is a contraindication of Gleevec.

Myocarditis - Inflammation of the Middle Tissue Heart Muscle is a contraindication of Gleevec.

Obesity - Overweight is a contraindication of Gleevec.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Gleevec.

Thyroid Surgery - Surgery on the Thyroid Gland is a contraindication of Gleevec.

Valvular Heart Disease - Heart Valve Disease is a contraindication of Gleevec.

Gleevec has 4 related brands and strengths:
 
Gleevec 100 Mg Tab

Gleevec 400 Mg Tab

Imatinib 100 Mg Tab

Imatinib 400 Mg Tab

Gleevec - Symptoms of overdose may include
severe muscle cramps, dark urine, abdominal swelling.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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